Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID50138	Gavestinel	GSE92742	HA1E	Human	6h	10uM	EID0247

Response Information :

Types	Number	Response transcription factors
Up-regulation	382	PPARG; ZNF331; NEUROD1; SSBP2; KDM5A; KLF3; ZFY; WWP1; ELF3; GATA2; MEF2C; MXD1; ZNF701; CREM; EGR4; SCRT1; EGR2; EGR3; ZIM2; SKI; CEBPD; ZFPM2; THRB; TBR1; ZNF835; KLF4; NRBF2; E2F2; OVOL1; ASH2L; NR5A2; HIC2; PLAGL2; BRWD1; MLLT1; NFIX; TFCP2L1; NFX1; ZNF614; NR1H2; AFF4; SOX21; TWIST1; TLX3; ZNF334; ZNF132; ZNF287; ZNF225; WHSC1L1; CARF; ZNF215; ZFP2; SOX18; TEAD1; SALL2; STAT5A; ZNF180; ZBTB44; EMX2; HIC1; PEG3; CAPN15; FOXD3; ZNF165; CHD2; TEF; ZNF253; FOXI1; ZNF432; GRHL2; SMARCA1; SAP130; FOXA1; GFI1B; ZNF41; ZNF506; FOXG1; ZNF75D; ZBTB6; NR4A1; LIMD1; MKL2; HDAC11; NR5A1; ZBTB3; ZNF442; ZBTB20; NFIL3; TFAP2B; TFE3; ZNF223; ASH1L; ASCL2; ZNF764; RERE; TULP2; PRDM16; ZNF135; HNF1B; NR2E1; ZNF391; ZNF214; SMARCA2; GCFC2; GCM1; ATF7IP; ZNF471; TXNIP; LZTS1; HDAC6; PRDM2; PRDM1; ZNF136; HOXC5; EHF; ZNF507; ZNF350; FOXB1; DDX17; ZNF780B; ZNF550; CBX7; IFNB1; RELB; PITX1; WT1; NR4A3; ZNF200; TCF21; MED31; EPAS1; NR2F1; TMF1; HOXA2; ZNF571; MAFB; THAP1; ZIC1; ZNF623; SOX17; OLIG2; CDX1; IRF6; PRDM5; FEZF2; POU6F1; ZNF669; ETV3; ZXDC; SMARCA5; TAF5; PPARA; NR4A2; TAF6L; UBTF; ZNF407; ZNF510; ZNF85; ZNF528; CUX2; TCF7; DOT1L; ZNF549; NFAT5; HMGB3; ZNF112; KLF10; FOXN1; NFIB; ZFP37; SP1; IKZF3; JAK2; MAP3K10; FOXH1; NKX2-1; STAT2; ING4; ZNF749; GON4L; SSX1; SUV39H1; FOSL1; RSF1; LHX6; NEUROD2; MED7; ZNF10; ZNF157; NANOG; ZNF783; BRDT; ORC2; POU2F3; WNT4; KAT6A; GATA1; NR1H4; DNMT3B; PBXIP1; BNC2; SSBP3; ZNF674; HOXB2; PAX4; ZNF154; ZNF273; MEIS1; NFYA; SOX5; MSC; ZNF222; ZNF813; CIITA; NFATC4; PAX8; CBFA2T3; MED21; TBX3; ZNF80; SUV39H2; GCM2; ZNF460; BHLHE41; AHR; GLI2; PLAGL1; ZNF35; TRIM29; MAF; NPAT; MAX; POU1F1; CEBPG; KLF12; TFDP2; AIRE; TRPS1; CCNE1; KDM5D; ZNF160; GFI1; PRRX1; AGO2; PKNOX1; HCFC1; CRTC1; ZNF219; ZNF675; MEOX2; SOX3; EBF2; MYT1L; TRIM28; MAK; FOSB; PRDM10; ZNF443; PIR; ZNF721; ZEB1; YBX2; ZNF117; THAP10; ZNF254; PSMC3; EGR1; ARRB1; MYBL1; ZNF771; ECD; TBX2; ZKSCAN7; ZNF337; ZKSCAN8; SIM1; ZNF141; TFEC; ZNF226; KAT2B; ZNF492; MBD4; ZMIZ2; KAT5; FOXL2; RORA; CIZ1; ZSCAN9; ID4; ZNF711; RBPMS; ZBED2; PML; IRF5; RBBP5; DYRK1B; MECOM; CBX6; E2F5; ZNF257; AEBP1; ZNF208; KAT8; CREB3L1; NR1I2; FOXO4; ZNF682; ZNF274; PIAS3; TRRAP; BRCA1; TBX21; LHX2; SNAI2; TFAP2C; TRIM33; BHLHE40; LIN28A; ZNF91; PRDM14; SMARCD3; NCOA2; HEY1; ESR1; NCOA1; RNF141; GATA3; PITX2; SHOX2; ELF5; TSC22D1; LITAF; CD3D; MAFG; MLXIP; RFX2; CARHSP1; ZNF43; KLF11; NR3C2; NFE2L3; HDAC9; MED12; RUNX3; ZFP36L2; CERS4; ZNF415; OSR2; REL; FOXJ1; ZNF611; NLK; ID1; STAT4; RARG; NAB1; MNT; HLF; BCL11B; ZNF93; TCF7L1; MITF; PBX3; CREBL2; TSC22D3; TERF1; PURA; ASCL1; ZNF83; NR1D2; ZNF587; NR1H3; TOPORS; ZNF304; AR; ZNF329; LEF1; BBX; IRF4; ZSCAN18; PSIP1; CRK
Down-regulation	469	HMG20B; SCAND1; NRIP1; DRAP1; ATF1; CDK2; ATF6; HOXA5; TLE1; NR2F6; ILF2; HDAC2; RUVBL1; MAZ; AES; LOXL2; RHOA; PSMD9; RFX5; ZNF593; ATF5; PBX1; DEK; THAP11; NKRF; PCGF1; RNF138; PMF1; DNMT1; IKBKAP; SUPT4H1; SNW1; SUB1; AIP; SF1; ZNF580; CCDC59; BPTF; ZNF146; TCF3; BRD8; RNF10; HDAC3; FOXO3; THAP4; SMAD4; VEZF1; CBFB; YEATS2; TCERG1; ARID1A; PATZ1; SMAD7; ZNF646; BIRC2; HOXA7; PHF1; TSG101; ARID4A; TAF7; SMARCD1; ZNF131; EDF1; ELF1; KMT5A; ZNF24; FOXJ3; ATF4; HOXA10; CDYL; DR1; HOXA4; RNF4; FLNA; JUND; WWC1; SMARCB1; RNF6; TSC22D2; PSPC1; HHEX; MTDH; TAF6; ZNF410; SREBF2; SETD3; TAF10; TCF12; ERG; MLLT10; ZBTB7A; TBL1XR1; ZNF668; ERCC3; IRF7; RBBP8; DNAJC2; RAN; GTF3A; GTF2IRD1; ZBTB11; CENPF; PRRX2; SMARCC2; ATF2; ZNF446; SUPT6H; ZFHX3; ZBTB1; ZZZ3; CHD4; NFE2L1; MTF2; MED13; ID2; ZNF263; PHF2; SP110; FOXN3; SIX5; TRIB3; FUBP1; HMGXB3; ZNF444; ZNF292; PMS1; SIRT7; TCF4; RBM39; USF2; ARL2BP; SRCAP; DAXX; USP21; C1QBP; TDP2; ERBB2; BANP; MED17; VSX1; BCLAF1; HABP4; CALR; SAFB2; NCOA6; ZMYM2; TBX10; PA2G4; APBB1; HDAC7; CRY1; ENY2; MED24; SP100; MNAT1; BRD4; HOXB3; ZNF76; APEX1; BCL3; BRD2; USP16; TFAM; SP140L; RNF14; ZMIZ1; ARID5B; MED1; LDB1; SMAD2; ZNF140; RFXANK; MXD3; VGLL4; CEBPZ; NEDD8; UBP1; HCFC2; ZHX2; UIMC1; BTAF1; ZFHX2; TRIM27; YAF2; TLE4; SIN3B; ZBTB17; HOXC6; IRF2; CHD9; ZNF768; PIAS1; SERTAD2; MLX; SP3; HMGXB4; ATN1; NFYB; SUPT3H; MBD3; NFRKB; ID3; PAXBP1; MYRF; TGIF1; TOB1; MSL3; KDM2A; ZNF45; CHD1; RXRB; ERF; SOX12; TRIP4; CBX5; ZKSCAN5; HMX1; TAF11; ACTL6A; RNF2; ITGB3BP; RCOR1; ZSCAN5A; BCL10; TBL1X; DEAF1; TONSL; WDHD1; BMI1; THAP3; SMAD3; RBFOX2; ING1; PSMC3IP; ARID4B; MEF2A; CHD7; ELK3; FOS; ZNF12; CERS6; POLR3C; NPAS2; CBX4; SPEN; HMG20A; EWSR1; ZFHX4; ZFP64; SOX9; TFCP2; TGIF2; NELFB; ZSCAN2; WIZ; TBX6; MED23; ZNF217; NR2C1; ZNF143; ZFP36L1; MED27; PIAS4; PHF20; TRAF6; SALL1; ABT1; CENPB; CARM1; ZNF232; ELF2; HOXC11; PDLIM1; ZNF84; MEF2D; ZNF562; PRDM4; TCF25; CSDE1; MYNN; JUP; TRIM32; CEBPE; PAX5; POU2F2; ZNF7; EHMT2; HIVEP1; MMS19; MYT1; KDM5C; ING3; HDAC4; TEAD3; CHD3; ZNF654; ALX1; HINFP; IKZF5; TAF1D; BATF3; PAWR; ZNF652; E2F8; ZNF148; PPRC1; TAF5L; TCEB2; MGA; CDC5L; ZNF536; RYBP; BTG1; ZFP30; TCF15; HAND1; CITED2; BRCA2; E2F3; TADA3; XRCC6; POU2AF1; RNF111; RBBP4; NRF1; PEX2; SOX15; CBX3; ESR2; TRIM16; FOXK2; E2F6; DLX2; ZNF202; WWTR1; ZNF512B; NHLH2; ZNF639; NAB2; CCNC; HLTF; SAP18; KLF6; STAT1; ZNF467; MDFI; LHX1; MAML1; DDX54; HOXB9; MED6; NFKB1; ARNTL; CREG1; DMTF1; ZBED4; MED14; VDR; HIRA; TFEB; ZMYND8; CNOT1; CTBP1; GLI3; ZNF384; ZNF345; CHD8; ZNF426; CREB1; SAP30; ZSCAN12; HOXC10; ATF6B; ZNF516; ZNF423; SOX11; HMGB1; MTA1; IRX4; ARNTL2; CRYM; MSX1; DNAJC1; YWHAB; PTTG1; PBX2; AATF; COPS2; HMGN3; HOXB6; SIX2; EP300; TERF2; ADNP2; SIAH2; ZMYND11; MBD1; UBE2B; THRAP3; ERBB4; ETV4; MEIS2; HOXB7; KLF7; ARID5A; RCOR3; HSF2; TSC22D4; YEATS4; RAD21; THRA; ZNF8; NKX3-2; UBE2I; DDIT3; MAGED1; YBX1; HTATIP2; HMGB2; ZNF3; CREB3L2; PAX6; ZBED1; INSR; ZNF267; SMAD6; ZNF302; TGFB1I1; SIRT2; IFI16; DPF2; NCOR2; PFDN5; ZNF354A; TOX3; TOX; MECP2; KAT6B; ATF3; POLR2A; BACH2; FOXD1; SIX1; ZNF184; COPS5; MXI1; WHSC1; HOXD1; SMAD1; SIM2; HOXC4; ZNF551; EN1; CREB5; ZBTB18; FOXF1; AFF1; EYA1; TULP4; MBD2; TRIP6; TRIM22; NR2F2; TCF7L2; IRF9; STAT3; FOXO1; TCEA1; MYCN