Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID50107	Dosulepin	GSE92742	HA1E	Human	6h	10uM	EID0247

Response Information :

Types	Number	Response transcription factors
Up-regulation	402	ADRB2; PPARG; ZNF331; ZFY; ZNF701; CREM; KLF3; SSBP2; KDM5A; GATA2; SKI; PIR; ZNF394; TFCP2L1; ASH1L; OVOL1; ELF3; GRHL2; NEUROD1; ZNF132; IKZF2; CEBPD; BARX2; IRF5; TAF12; TRIM24; PAX9; EGR2; FHL5; ZNF117; PIAS3; ZFP36L2; NRBF2; SSBP3; AFF4; ZNF165; NR1H2; IRF6; ZNF253; PLAGL2; MXD4; WWP1; WHSC1L1; THRB; ZNF696; HNF1B; GFI1; TMF1; CDIP1; SMAD5; ZNF205; NR4A3; KLF4; POU5F1B; ZBTB25; POU6F1; AFF1; PNRC1; EVX1; ZIM2; ZNF273; ZNF665; HDAC11; EMX2; TWIST1; ZNF107; SPIB; ZNF669; SMARCA2; BNC1; NKX2-1; ZNF44; CBX7; ONECUT2; ZNF286A; KAT6A; LZTS1; BRWD1; PHOX2A; PITX1; TXNIP; ZNF225; OSR2; MLXIP; NFIL3; KLF5; KDM5D; NFX1; LIMD1; KAT2B; SMARCA1; NANOG; CHD2; NSD1; PHIP; NR1H4; ZNF550; CTNNB1; HIC2; MAF; ZNF710; PRDM5; TCF7; ZNF835; AHR; LHX6; ID1; ZNF223; AEBP1; HOXA2; PEG3; TAF4B; CIITA; MECOM; ZNF142; ZNF764; ARID3A; NR4A2; SOX21; ZNF516; KLF10; ZFPM2; ZNF160; NCOA2; NFAT5; CBL; TP73; ORC2; SND1; SOX17; ASCL3; TBR1; LIN28A; TFDP2; ZNF606; ZNF224; ZNF432; TAL1; CAPN15; SMARCD2; EGR1; CDX1; PAX8; MYCL; ZBED2; EYA3; SHOX; ZNF391; VGLL4; ZXDC; ZNF721; CD3D; SSX7; RELB; FOXH1; ZNF136; SMARCA5; TCFL5; EMX1; TBX19; EGR3; YY1; RORA; IKZF1; CUX1; HDAC6; ZNF611; FOSL2; ZNF443; TBP; STAT5A; NCOA1; TRIM22; EGR4; ZNF695; KDM5B; TBX1; OVOL2; RARA; NAB2; NCOA3; SKIL; SAP130; RFX2; NFYA; ZNF304; ZNF85; PRDM1; NR4A1; RAX; TTF2; NFATC4; ZSCAN18; NR2F1; HLF; PURA; BCOR; ZNF264; NFE2L2; ZNF816; BATF; FOXG1; FOXE1; MYBL2; ZNF222; MEIS1; ZBTB3; ZNF587; NR2F6; PROP1; ZNF813; NFKBIB; TOPORS; ZNF221; BHLHE40; PRDM14; BAZ2A; EZH1; BCL11B; ZNF415; ZBTB24; TULP4; PRRX1; ZNF141; ZNF551; ZNF267; ZNF208; TRAF6; ZNF667; PRKDC; ETS1; RARG; NR1D2; SSX3; BRPF1; SSX1; NFE2; UTF1; GATA1; STAT5B; ZNF493; PML; SAP30; ARRB1; TFEC; ZBTB39; HR; MEF2C; ARID3B; RSF1; GFI1B; EHF; KLF9; ZNF440; ZHX3; POU2F3; BRCA1; ZNF350; HOXA1; TFE3; ZNF571; STAT2; WDHD1; ESR1; BCLAF1; FHL2; ZNF93; SP1; CARF; TAF4; ATF7; RBPMS; MAFF; IKZF3; ZNF329; ZNF91; MITF; ZNF682; TERF1; TBX2; ADNP; ZNF629; FOXJ2; NCOR1; TGS1; YBX2; MXD1; NFE2L3; TBX21; ATF7IP; ZNF780B; TRRAP; ZNF124; NKX2-5; FOXO4; ZNF337; ZBTB44; AGO2; ECD; CHD4; SNAI1; OLIG2; DNMT3B; THAP11; MED12; TSC22D1; SMARCA4; MMS19; REL; SFPQ; PARP1; ZMYND8; CBFA2T3; TCF21; ZNF492; ZNF274; KLF6; EPAS1; TRIM33; TAF1; FOXK2; SCMH1; RUNX3; DYRK1B; HMGA2; PIAS2; CTR9; NR3C2; ZNF460; CREBL2; SOX4; ZNF226; ZNF532; ZNF419; ZNF180; E2F2; PHOX2B; ETV6; MYT1L; BARX1; TSC22D3; IRF4; ZNF217; RREB1; HIPK2; CBX6; RBBP7; GATA3; MBD2; PBXIP1; TBPL1; SIM1; HDAC9; ASCL1; PPARGC1A; NR5A2; L3MBTL1; MKL2; LEF1; MAFG; TOX; JUNB; EYA2; NFATC1; RERE; NFATC3; ZNF175; LYL1; ARNTL; CUX2; PBX2; BLM; RBPJ; YBX1; CTBP2; MYBL1; ZNF33B; CASZ1; ZNF552; EP300; TCF7L1; XBP1; ZNF430; JUN; MYB; PCGF2; CCNE1; FOXA2; PRDM2; ZBTB16; EZH2; TAF9B; TRPS1; CITED2; ERBB4; ZNF134; TP63; ID4; ZKSCAN1; STAT3; CRK; PSIP1
Down-regulation	469	LOXL2; PUF60; HMG20B; SCAND1; NRIP1; DRAP1; CDK2; ATF1; EDF1; TLE1; ABL1; RB1; MAZ; ZNF593; BTF3; NUP62; PSMC3; SF1; ITGB3BP; RUVBL1; PSMD9; DEAF1; ILF2; RHOA; GTF2A2; HDAC2; ATF6; ZNF589; CBX3; JUND; TCEA2; ATF4; ATF5; CCDC59; PCGF1; ZNF410; PATZ1; NELFB; GMNN; APEX1; RBFOX2; TAF6; FOXO3; MED27; RAN; RBM39; ZNF146; RFXANK; SMARCB1; HMGXB4; CDYL; DEK; CDC5L; XRCC6; PMF1; SUB1; SIN3B; ZNF140; GTF2IRD1; TCF25; DNMT1; ARNT2; TAF10; PA2G4; ZNF580; SMARCD1; CENPB; ERCC3; PIAS4; ZZZ3; NFYB; MGA; ARID1A; RNF4; CBFB; VPS72; GTF3A; IKBKAP; NCOA4; USP21; TRIP4; UBE2L3; TLE4; NFRKB; SP140L; ACTL6A; AIP; AES; MYC; SREBF2; CHD8; YAF2; ZNF24; TAF9; SP110; SP2; SUPT4H1; PHF1; TSG101; PTTG1; HMGXB3; HNRNPD; CNOT3; BASP1; YWHAB; ENY2; GMEB2; CCNA2; WWC1; CDK7; PHF20; BIRC2; ZBTB18; DLX2; ELK3; CEBPG; FOXJ3; BRD4; ATF2; PMS1; MEOX1; APBB1; VSX1; CBX5; VEZF1; ARID5A; CENPF; ZNF444; TEAD4; TFAM; HOXA7; HDAC3; TCF3; MTF2; ZFHX4; ZNF668; MED16; SHOX2; HOXA5; MBD3; C1QBP; TRIB3; IRF2; KDM5C; KAT5; MXD3; ZNF536; WIZ; GLI2; MLX; NACA; CRY1; HMBOX1; NFKB1; SUPT6H; ZNF446; ELK1; BANP; DAXX; SOX9; ARID5B; DR1; LZTR1; SPEN; UBE2I; BATF3; MYRF; ZBTB7A; RXRB; HOXB2; PRPF6; ERBB2; ZNF263; ATN1; ZNF302; ZNF131; HSF1; ZNF232; PBX1; NCOA6; BMI1; ZNF268; FOXN3; CTCF; PHF2; SP3; TRIM16; PTRF; CALR; ZBTB17; ARL2BP; SETD2; RNF2; POLR3F; ELF4; ZNF177; MZF1; PBX3; SRCAP; IRF7; REXO4; USP16; MYNN; TADA3; SMAD3; MED13; ETV4; CCNC; NONO; HDAC4; CHD7; TOX3; ZMIZ1; BLZF1; RNF138; CREB5; ZNF202; ZBTB11; NKX2-2; C1D; PSMC3IP; ZNF250; PRRX2; SALL2; SNW1; PSPC1; FOSL1; ARID4B; PDLIM1; NKRF; PAXBP1; BRD3; PQBP1; NR2F2; SOX11; WDR77; RFXAP; NPAS1; TONSL; HIRA; ZNF76; USF2; GATA6; SERTAD2; NR2C1; ZFX; GBX2; HOXA10; FOXM1; NKX3-2; MYF5; ZNF276; SUPT3H; ZEB1; MED17; RNF10; BCL3; SMARCD3; SETDB1; ID3; SMARCC2; COPS2; RBBP8; BACH2; ZSCAN12; NHLH2; BRD2; NOC2L; ZNF7; ZNF148; GLI3; TRIM32; HDGF; TCF4; CAMTA1; TGIF2; BRIP1; TOX4; TBL1X; CSDE1; SIRT2; ATF3; ZNF426; TDP2; VAX2; BTAF1; SNAPC4; RBM14; NCOR2; TGIF1; UIMC1; HOXD9; NEDD8; CHD1; HOXC6; IRF3; CTBP1; NAB1; MED6; RING1; ZBED1; DNAJC1; TRIP6; KDM2A; ZFHX3; ZNF692; THAP10; MDFI; PRDM10; PBRM1; HOXB6; NPM1; GCFC2; ZNF512B; MYOG; WHSC1; ZNF16; CBX4; EWSR1; ZIC1; CIZ1; WWTR1; UBP1; ZFP64; ID2; BAZ2B; ENO1; HOXB5; HAND1; SOHLH2; ZBTB48; HSF2; SPI1; TAF11; HOXB1; HOXB13; ST18; RAD21; TBL1XR1; PHF8; RYBP; HSBP1; ARNTL2; TTF1; ZHX2; PEX2; MLLT10; CHD9; CEBPB; THAP7; SOX10; CIC; ZBED4; HOXB3; POU2AF1; HOXD10; PAWR; LHX1; MED21; JUP; GATAD2A; ZNF22; FOXF2; SREBF1; THAP4; ERCC2; NFYC; RELA; HHEX; E2F3; ZNF266; TAF1A; FLI1; ZNF639; ZKSCAN5; TRIM27; BRCA2; E2F8; RCOR1; RFC1; PFDN5; MEF2A; ERF; IRF1; MED7; TDRD3; ZNF45; MTA1; RUVBL2; ZNF143; DMTF1; IRX4; TFAP2C; SPDEF; TSC22D2; HINFP; ZNF500; ZNF562; ASXL1; VDR; ZNF84; ZNF467; STAT1; LITAF; FLNA; SALL1; SIX2; TLE2; POU3F2; GTF2F1; MTDH; CARHSP1; MECP2; NR0B2; CREG1; DPF2; KLF7; PCGF3; CITED1; EN1; NRF1; SATB2; HIVEP1; MXI1; RNF111; STAT6; HMGB1; KAT6B; REPIN1; SIM2; IRF9; TERF2; ZNF32; TCF7L2; ERG; CNBP; BNC2; FOS; ZFP36L1; FOXF1; RUNX1; HLTF; ELF2; POU2F1; PAX6; NPAS2; TGFB1I1; YAP1; NKX3-1; HMGB3; BCL6; FOXO1; SAFB2; PAX5; ZBTB38; ING3; RBBP4; ETV5; MNAT1; TRIM29; NFIB; MSX1; BAZ1A; INSR; HTATIP2; INSM1; KLF2; BHLHE41; MEOX2