Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID50104	Dihydroergocristine	GSE92742	HA1E	Human	6h	10uM	EID0247

Response Information :

Types	Number	Response transcription factors
Up-regulation	478	NKX2-2; ADRB2; WWP1; PPARG; ZNF701; ZFPM2; CREM; KLF3; OVOL1; NR5A1; KDM5A; NRBF2; NFE2; SSBP2; NEUROD1; ZBTB7C; BRWD1; MLLT1; NCOA1; ASCL2; POU1F1; NR5A2; EVX1; VGLL1; CHD2; BRPF1; FHL5; CSDC2; SSX1; PRDM1; ZNF343; NR1H4; HNF4G; GATA2; ZNF695; HIC1; TCF15; ZNF764; TAF12; ZNF667; ARID3B; TBX1; KMT2B; ZBTB44; HIC2; NR0B1; BPTF; MEF2D; HAND2; TFCP2L1; PEG3; CEBPD; TMF1; BNC1; LYL1; PITX2; DMRT1; ZIM2; ZBTB39; IKZF3; HDAC11; EGR4; HLF; OLIG2; KLF10; ZNF205; FOXB1; GATA6; HOXA3; RORA; HMX1; ZNF710; SOX21; ZNF227; STAT2; BRDT; ZNF225; ZNF391; WNT4; ZNF41; ZNF571; ZNF135; SCRT1; PLAGL2; SKIL; FOXD3; CBX8; SIX5; MAML3; BARX2; ZBTB3; ZNF516; ZNF107; SPIB; HDAC7; SMARCA1; ZNF75D; HOXC5; IRF1; TCF21; ZFP36L2; ZNF226; UBTF; ZNF573; ZNF281; NR1I3; ZNF131; ZNF623; ZBTB6; ZNF646; ELF3; NR6A1; ZNF236; TFAP2B; PAX4; MNX1; PAWR; POU2F2; ZNF440; AFF2; DOT1L; ONECUT1; SKI; ZNF682; ZNF180; PAX9; ZNF674; ZNF235; IKZF1; ASCL3; ZNF331; PROX1; ZNF665; THAP9; MYBL1; SMARCA2; ZNF671; ZNF214; ZNF768; ASH1L; FOXN1; FOXH1; TEAD3; TRPS1; CDX1; PML; NKX2-5; EGR2; TFAP2C; LPIN2; SSX7; ZNF835; RFX1; GATA1; FOXL2; MYB; BACH1; ZNF80; SOX18; PRDM10; TEF; HCFC1; UTF1; FOSL2; GCM1; ZNF696; PRDM8; ZNF629; E2F2; NR1D2; EHMT1; LMO1; MED14; AIRE; SND1; ZSCAN16; NEUROG3; MLXIP; ZNF112; TRIM33; ZNF813; ZNF117; NKX2-1; AEBP1; PPARA; ZNF223; HMG20A; ZNF222; ZNF257; MSC; CAPN15; CREBZF; ZNF721; ZNF493; BLZF1; EP400; ZBTB43; NKX2-8; TBX21; SOX3; ARHGAP35; POU3F3; NLK; ELF5; PROP1; ZXDC; MLXIPL; CALCOCO1; BAZ2A; JUNB; ZNF780B; GCM2; PAX7; ZNF507; GFI1; ZNF211; GSC2; ZNF157; ZNF224; ZNF165; FOXD2; DLX4; NR1H2; BAZ2B; PBX2; ZHX2; CBX7; ETV7; HOXD13; ZNF492; CIITA; ZNF557; POU3F4; MAP3K10; ZNF550; ERG; ZNF215; MAK; RAX; ELF4; KLF4; ZNF234; ZNF551; VHL; DDX54; ZNF350; MAFG; HDAC5; HCFC2; FOXO4; HNF1A; TBR1; ZXDB; TBP; ZKSCAN4; DDX5; FOXK2; ZNF160; TCF7; E2F4; RUNX1; EMX1; HR; ZFP2; ZNF358; POU4F3; ZNF814; NKX6-1; ZNF711; ZNF442; LHX3; SNAPC4; ONECUT2; DNAJC1; ZNF446; KDM5C; E4F1; TONSL; GFI1B; ZNF471; GATA4; BCOR; FOXJ1; NFAT5; MYBL2; ZNF221; CCNT1; ETV2; POLR2A; SHOX; ZNF587; AGO2; CARF; SP4; TLX2; TBX19; KMT2D; HEYL; BBX; KAT6A; KDM4C; SUPT5H; ZHX3; ETV3; RFX2; KAT2B; THRB; MYT1L; E2F5; SRY; EN1; TOPORS; SUV39H2; POU2F3; CAMTA2; ZNF407; SOX13; TFDP3; IRX5; SSX3; TBX4; ZNF81; FOXE1; TRIM24; CBFA2T3; TLX3; PGR; ING1; ZNF778; TBX3; YEATS4; ARNT; SUV39H1; ATOH1; NFE2L3; MYF6; PBXIP1; ZNF200; YBX2; NR4A1; ZNF329; DYRK1B; ZNF292; IRF6; OVOL2; PKNOX1; HESX1; CALR; ZNF787; INSR; PITX1; REL; STAT4; ZNF22; WHSC1L1; ZNF254; CTNNB1; ESR1; MED13; TULP4; SMARCD2; L3MBTL1; HOXA1; SMAD7; RARA; BCL3; HIVEP1; ZNF141; AFF1; CARHSP1; NAB2; ZNF267; EGR3; YAP1; ZNF460; TLE4; SIM1; ZNF212; ZNF556; E2F3; ZNF473; DBP; TAF1D; NR2F1; TWIST1; ZBTB38; ZSCAN9; NEUROD2; VENTX; ZBTB16; TSC22D2; LHX6; EPAS1; STAT5A; JUP; RSF1; LIN28A; HMGB3; FOXA1; LIMD1; ZNF91; ZNF304; SMAD4; CIC; TGIF1; RUNX3; IFNB1; ZFX; ZNF771; TSC22D4; TBX2; CHAF1B; ZNF510; SOHLH2; RARG; NPAT; PRDM14; DDX17; NR3C2; TGFB1; FOXJ2; VGLL4; EP300; SIRT7; PRDM2; GRHL2; ZNF264; CXXC1; PPRC1; ZNF611; BCL11B; VDR; ZNF415; KLF9; TTF2; FOXO1; GATA3; NR1I2; TFEC; ASCL1; ZNF83; NANOG; ZSCAN31; HTATIP2; CREB3L2; WT1; AHR; ZNF10; SATB1; ZNF468; UBE3A; ERBB4; NR4A3; FOXC1; CUX2; ZBED4; OSR2; NR4A2; ZMIZ1; MAFB; CEBPZ; PURA; ZBTB20; SIAH2; MAGED1; MYCN; BAZ1A; TCF7L1; DDIT3; TRIB3; HDAC9; EHF; FOXA2; IRF4; FOXG1; ID4; ZSCAN18; SOX2
Down-regulation	480	LOXL2; PUF60; HMG20B; SCAND1; EDF1; ILF2; NR2F6; TLE1; CDK2; ABL1; GTF2A2; DRAP1; ITGB3BP; HIF1A; RUVBL1; ATF6; DEK; MYCBP; CENPF; ATF1; CDC5L; PTTG1; ENY2; CTCF; HDAC2; GMNN; RNF4; GTF2IRD1; PSMD9; USP22; SSRP1; ZNF589; RHOA; TFDP1; MYC; C1QBP; NUP62; PSMC3; DNMT1; APEX1; RFXANK; PMF1; CARM1; THAP11; RAN; AIP; PAX8; BRD8; CBX3; MTDH; RBM39; WIZ; TRIP6; YBX1; JUND; PCBD1; NKRF; DEAF1; CCNH; NELFB; NEDD8; ETS1; GTF3A; ECD; XRCC6; SNW1; UBE2I; ATF2; HDAC3; UBE2L3; ZFP36L1; CBFB; GABPB1; TAF7; TAF10; MED27; FLNA; HSBP1; CCNA2; AES; RBBP8; DR1; HNRNPD; RAD21; SLC2A4RG; NOC2L; RFX5; CDK7; TAF9; HMGXB4; SP2; CTBP1; SALL2; NPM1; WWC1; BRD7; SMARCC1; ZNF580; PATZ1; CIZ1; TCF12; SIN3B; SP110; RNF138; TAF6; FOXO3; HOXB2; FOXJ3; SMARCA4; TCERG1; CCDC59; BTF3; MGA; REXO4; HOXA10; MED24; PHF20; USP21; MLX; ZZZ3; CHD8; NCOA4; MED21; ERCC3; TDP2; HBP1; RBBP4; PCGF1; HOXB6; FOXF1; COPS5; SNAI2; C1D; YWHAB; PBX3; CREB3; CCNC; ZNF268; KDM2A; RFC1; COPS2; PDLIM1; TCF25; ZNF410; TAF11; HMGB2; HMGB1; RBM14; GMEB2; CNBP; GTF2A1; MTF2; CTR9; PRPF6; USP16; TSG101; SUB1; ARNT2; PEX2; NRIP1; MAML1; SETD3; CRY1; CBX5; MED4; SMARCD1; ARID1A; NCOR1; PTRF; ZNF266; FOXM1; CSDE1; SP140L; HOXA11; TTF1; KAT5; RNF6; ADNP2; ZNF146; PSMC3IP; ARL2BP; ZBTB1; LITAF; SUPT4H1; HLTF; ZNF593; VPS72; MXD3; ZBTB17; TRIP4; NFYC; ERBB2; JUN; SIM2; ZBTB7A; MED1; MED23; MED6; ZNF133; RBFOX2; TBL1X; ZNF140; BRD4; ZNF23; MAZ; HEY1; ARID4A; TERF2; CTBP2; SREBF2; ATF4; MNAT1; TFCP2; ZNF335; CHD1; HOXA7; FUBP1; MEF2C; KMT5A; ZFP64; PIR; NR2C1; FOXP3; WWTR1; SP3; IFI16; TP53; TGS1; CEBPG; SOX9; TRIM16; ZNF274; TULP3; HMGXB3; CNOT1; RBPJ; ASXL1; NCOA6; SMARCC2; BNC2; IRF9; ZBTB18; ZNF24; ZBTB11; ATN1; HOXD9; ZNF562; BCL10; CHD9; ACTL6A; THRAP3; LDB1; BASP1; ZNF423; NFRKB; NSD1; THAP3; THAP4; MAX; CHD7; MTF1; SP100; SMAD2; CREB5; ENO1; PHF2; CDYL; ZFHX3; CNOT6; MXI1; NONO; PCGF2; TRIM29; TFAM; MEIS1; PAXBP1; GATAD2A; EZH2; WHSC1; HOXA5; GTF2F1; TBX6; MYNN; BAZ1B; ZNF12; POLR3F; MED16; ZNF528; MED17; TUB; MED20; FLI1; HOXB5; RCOR1; URI1; SUMO1; ID3; SOX15; ELF1; TRRAP; HMGN3; MDFI; ISL1; SMARCB1; CENPB; ARNTL2; ZNF302; ZNF248; PMS1; CERS6; THAP7; EHMT2; SNIP1; ADNP; DNAJC2; TOX4; ZNF195; SETD2; MITF; CDK8; PRMT2; TERF1; BRD3; ELK3; ATF6B; SAP18; TRIM27; PSPC1; ZNF84; WDR77; ZSCAN12; UIMC1; STAT6; TCEA1; ACTL6B; TADA3; PBX1; HDGF; MEOX1; CBFA2T2; ZBED1; ZNF672; SERTAD2; HOXB3; HES1; CITED1; ZNF32; ZNF426; HDAC1; MNT; RBPJL; ZNF45; SIX2; NHLH2; CCNE1; REST; ZNF148; SAFB2; STAT1; CITED2; DPF2; ZNF232; ZNF512B; PRRX2; MSX1; UBP1; PKNOX2; GLI3; SIX1; RUVBL2; TOB1; ATF3; ZBTB48; HOXD10; ZNF7; EMX2; ETV5; SOX11; ZNF202; THRA; IRF7; REPIN1; MECOM; MZF1; PBRM1; ZKSCAN5; HAND1; ZEB1; SMARCD3; ZNF143; FOXD1; ZNF783; YBX3; CRYM; PEX14; RNF14; CREBL2; PFDN5; ZFHX4; PHF1; LHX1; NAB1; KAT7; ZNF692; NCOR2; DMTF1; ZNF217; KAT2A; ST18; DLX2; NFIC; ZNF263; KLF7; TSC22D3; CNOT2; MTA1; POU4F1; EWSR1; HIPK1; NKX3-1; BANP; GON4L; MED7; CEBPA; ETV4; SREBF1; RRN3; SMAD1; RCOR3; ING3; GABPA; PSIP1; HOXD1; BATF3; HINFP; NCOA2; ZNF3; HOXC6; ING2; RNF111; BMI1; ZNF544; FOXF2; CRK; IRF8; HIVEP2; TCF4; PA2G4; MMS19; PLAGL1; NPAS2; KDM5D; HOXD3; MYRF; TBL1XR1; RBL2; ZMYND11; SAP30; TAF9B; ARNTL; TFAP2A; SALL1; MAF; TCEB2; ZNF354A; TLE2; MBD2; SOX10; ZKSCAN1; ZIC1; CEBPB; TP63; EYA1; HIPK3; GTF2I; BHLHE41; STAT3; ID2; INSM1; NFATC3