Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID50102	Diazoxide	GSE92742	HA1E	Human	6h	10uM	EID0247

Response Information :

Types	Number	Response transcription factors
Up-regulation	414	PPARG; ZNF331; NEUROD1; ZNF701; SSBP2; ZFY; KDM5A; PRDM5; CREM; NFATC1; CIITA; KLF3; WHSC1L1; GATA2; CHD2; MXD1; ZNF835; MEF2C; ZNF528; MDM2; ZNF334; ZNF253; STAT5A; NFKBIB; SSBP3; ZBED2; ZIM2; GRHL2; SKI; ZNF287; PLAG1; ZNF165; NFAT5; ZNF493; ZNF217; CARF; EGR2; TAF4B; WWP1; IKZF2; OVOL2; ZNF132; AEBP1; DDX17; NFIX; ZNF623; ELF3; PIR; EGR4; E2F5; ZNF225; ORC2; SMARCA1; BNC2; SP4; CTCF; SSX1; PKNOX2; TAF4; BRWD1; ZBTB24; TEAD1; NFYA; E2F2; LIMD1; ZNF460; ZNF214; EMX2; RARA; TFCP2L1; TFE3; TBX1; ZNF780B; FOXE1; ZBTB3; ZKSCAN8; EHF; ZFPM2; EYA2; KLF4; GLI2; ZNF814; CTNNB1; HCFC1; ZNF492; ZNF682; RFX7; SOX18; ZNF816; HMGB3; LPIN2; STAT5B; ADNP; ZNF236; PEG3; TCFL5; WT1; ZNF157; NCOA2; ZNF549; KLF12; SOX17; ZNF711; TXNIP; ZNF215; LZTS1; THRB; HIVEP2; KAT6A; ZNF507; ZNF391; ZNF550; ZNF571; SPDEF; ZNF407; SSRP1; DMRT1; ZNF81; ZNF506; ETV1; ZBTB44; CBX7; ZNF223; NCOR1; FLI1; AFF4; NANOG; NFATC4; ZNF85; ZNF552; SOX13; IRF4; ZNF80; PRDM2; HOXA2; SALL2; ZNF286A; BCL11B; MAX; MLXIP; SMAD2; LEF1; KDM5D; ZNF442; PAX4; NSD1; IL16; ING2; LIN28A; NRBF2; CAMTA2; REST; ZNF667; ZNF471; PURA; HNF4G; ZNF93; TBR1; CBFA2T3; TULP2; NCOA1; ZNF337; BHLHE41; MLLT1; BARX2; HDAC6; NR2E1; BACH1; ZNF674; MDM4; ASH1L; ZNF749; TFDP2; SMARCA5; EGR3; PLAGL2; PITX1; HOXC5; ZNF629; FOXL2; CBX5; ARRB1; CEBPG; ZNF34; SSX7; ZNF696; URI1; NCOA3; BRD7; HIC2; HEY1; ZNF141; GCM2; PAX8; MKL2; PAX1; MAK; ZNF415; SOX5; RELB; HIC1; SOX1; PRDM1; MED12; ZNF345; NR2F1; MYBL2; HES1; NFKB2; TULP4; ZNF764; IKZF3; IFNB1; NR1H4; ZNF783; ZNF180; EBF2; EP400; SP1; ZNF695; THAP9; ASCL2; HSBP1; L3MBTL1; MAF; ZIC3; ECD; BCL10; RBL2; LMCD1; RFX3; OSR2; CCNH; THAP11; GATA4; POU4F1; PPARA; ZNF671; ZNF665; TCF21; HLF; ZKSCAN4; CD3D; ZNF573; KDM5B; ASH2L; TBP; ZIC1; CTR9; YBX2; ZNF254; STAT2; RSF1; ZNF14; VGLL1; NR3C2; FOXG1; ZNF529; TWIST1; EYA3; NFE2L2; HNF1B; YWHAB; ZNF443; ZNF813; RNF141; MAFF; BCOR; ZNF675; SOX21; KLF10; PRKDC; ZNF208; ZNF227; ZNF142; BATF; FOXO1; ATF7; NR5A2; POU2F3; AATF; PRPF6; ZNF75D; TERF1; ZNF778; PHIP; SMARCA4; BRDT; DNMT3B; TCF7L1; RUNX3; IKZF1; EGR1; NFYC; ZNF544; FOXO4; ZFP64; ZFP36L2; HIPK3; HMGB2; ZNF329; GABPB1; MECOM; SOX3; TSC22D1; NR4A1; ZNF556; ZNF274; ASCL1; ZFP69B; ZNF33B; EPAS1; NFE2L3; TAF5; ZNF136; RBL1; SIM2; SATB1; MBD2; ZBTB39; ZNF273; MYBL1; BACH2; PRRX1; MNT; PLAGL1; RREB1; PGR; TRPS1; CREBZF; TRIM24; SAFB; ZBTB38; ZNF107; NR1D2; BHLHE40; RERE; BRCA1; ZNF467; ZSCAN18; TSC22D3; SMAD5; HDAC1; ZNF587; TOPORS; HIPK2; ZNF710; HMGA2; TGIF2; ZNF350; ELF4; CNOT1; HSF1; SCAI; IRF6; ZNF117; HTATIP2; EED; MYCL; AGO2; CBX6; AHR; ZSCAN16; SMARCA2; GTF2I; REPIN1; YAP1; ZMYND11; CUX2; ZNF226; PRDM14; HEY2; TFEC; MECP2; ETS2; MED4; FOXA1; FOXJ1; CREBL2; MITF; PBXIP1; NLK; NR4A3; RBPMS; MYCN; FOSL2; TCF20; NR4A2; NFIC; RBBP4; E2F3; SNAI2; GATA6; TGIF1; KLF9; JUN; SAP30; TAF9B; AFF1; ZNF721; HOXC6; PCGF2; TOX; KLF2; IFI16; ID4; ELF5; ESR1; TBX2; TFAP2A; GATA3; CRK; PSIP1; NR3C1
Down-regulation	444	HMG20B; LOXL2; SCAND1; DRAP1; HOXA5; NRIP1; ZNF593; ABL1; GMNN; RNF4; HDAC3; ATF5; RFX5; DNMT1; PIAS4; PCGF1; EDF1; PSMD9; REXO4; ZNF131; ILF2; MED27; ZNF576; IKBKAP; VPS72; TAF6; BRD8; ZZZ3; ZNF446; SP110; RFC1; HCFC2; CREB3; PRRX2; TBX10; MBD3; HOXA7; USP16; ZNF140; FOXJ3; SRCAP; HOXA4; APEX1; STAT6; RNF138; RNF10; CENPB; ZNF358; PMF1; NFE2L1; TULP3; ZBTB17; HOXB5; HOXA10; BIRC2; MED21; MTF2; ZNF646; RBM39; GTF3A; PMS1; DEK; SUPT4H1; MAZ; ARHGAP35; PCGF3; SP140L; E2F1; TLE4; ZKSCAN5; PIAS1; RBFOX2; ZNF22; PATZ1; CDYL; ATF2; VSX1; ZNF263; HMGXB3; DAXX; SIRT7; DLX2; MED17; MED13; NKRF; TOX4; ITGB3BP; MED24; CEBPE; SIX5; ATF4; TRIB3; ZMYM2; ZMIZ1; ERCC3; PRDM10; THAP3; NELFB; YAF2; ZNF668; MED15; ZNF410; SUPT6H; CBX3; APBB1; RBBP8; NFKB1; MXD4; RAN; TRIP6; VEZF1; PHF1; CSDE1; ZNF146; TRIP4; ENY2; DNAJC2; NPAS1; ZNF23; NR2F2; ZNF335; SETD3; MEIS2; TFEB; BAZ2B; NOC2L; THAP4; BTAF1; THAP7; NCOA4; CHD8; HABP4; ABT1; TRIM32; TDP2; ZNF24; ZNF76; ZNF174; SPEN; EWSR1; NPM1; PDLIM1; TCF4; CDK8; BPTF; ARID5A; CHD9; HOXA11; CARM1; COPS2; ERBB2; UBE3A; KMT5A; ZNF580; CHAF1B; PHF20; CCNC; RFXANK; ARID5B; ZNF3; ARNT2; SMARCD1; PSMC3IP; MNAT1; PRDM4; KDM2A; SMAD3; ELF1; ZNF250; HBP1; NFRKB; ARNTL2; MED16; EVX1; FOXF2; DNAJC1; RXRB; WIZ; KAT2B; CEBPZ; ARL2BP; CHD1; SIX2; ZNF12; E2F4; HOXA6; ZNF500; MXD3; TUB; ZFHX3; VGLL4; AES; POU2F2; BRD3; TAF5L; HIF3A; UIMC1; BRCA2; ID3; MBD1; SMAD4; HOXB3; NKX2-8; KLF1; HOXD10; ZNF45; HINFP; SNAPC4; MAGED1; MEF2D; ZNF189; TCF3; HMGXB4; SMAD7; NFIB; KLF5; RNF2; GBX2; IRF9; ID2; TTF1; ZNF536; FUBP1; TCF12; BCL3; PAXBP1; ZNF232; ZMYND8; BAZ1B; JUNB; ZNF688; TONSL; ZNF562; SUB1; MSX1; ZNF276; MYOG; CERS4; RNF6; HOXD9; LZTR1; ARID4B; PBX3; SETDB1; PSPC1; ZNF268; CRY1; RYBP; CREB3L2; ZNF408; TSC22D2; CIZ1; HOXA3; SERTAD2; AIP; ZNF444; ZBTB7A; ZNF768; DLX4; ZBTB11; DACH1; DDIT3; BRIP1; TAF11; MAP3K10; TEAD3; DEAF1; ZSCAN32; BATF3; SIRT2; CREG1; RXRA; HIRA; PFDN5; MKL1; HOXB9; MMS19; KMT2B; CDC5L; BTF3; PITX3; LITAF; ARNT; CRYM; ZNF512B; ZNF281; HIPK1; MED6; BASP1; KDM4A; WHSC1; ZNF771; IKZF5; HIVEP1; ZFHX4; PA2G4; THRA; C1D; ZNF84; SF1; FOXF1; CASZ1; RNF14; ETV4; SFMBT1; DR1; ZNF200; CNOT3; MDFI; YBX3; UBE2L3; SUPT3H; TBX3; MYT1; ZBED1; KDM4C; TRIM16; SHOX2; ZNF292; MLX; AIRE; NAB2; ZSCAN5A; ZBTB48; ESRRB; TAF7; HOXD11; BANP; CNOT6; ING3; CBX4; WWC1; ADNP2; MLLT10; TCF15; MEF2A; NFYB; VAX2; FOXN3; ERG; ZNF32; MED23; XRCC6; ZFX; DDX5; SAFB2; FOXM1; HMGB1; ZEB1; SMAD6; PTRF; ZNF202; E2F8; TAF9; TOB1; PRDM12; ZBTB43; USP21; TSC22D4; HAND1; KLF13; ARID1A; ZNF652; C1QBP; SALL1; CTBP1; PML; SOX9; MTA1; ZNF468; CCDC59; TEAD4; IRF7; PITX2; TBL1XR1; TRIM29; FOS; SMAD1; BARX1; PEX14; DMTF1; POU2F1; BLZF1; PEX2; MYNN; ZSCAN12; ZHX2; KAT6B; WWTR1; KLF7; STAT1; ENO1; MXI1; GTF2F1; SCMH1; JUND; HMBOX1; BMI1; TERF2; RRN3; ESRRA; CALR; HOXD1; NR1H2; ZNF266; HLTF; YEATS2; ZNF8; ZNF611; FOXJ2; MAFG; MED1; ZBED4; CNBP; MYRF; ZNF516; SIX1; EP300; CREB3L1; ZBTB20; TOX3; ST18; TGFB1; HOXB2; CBFB; NR2C1; TCEA1; CEBPD; TFAM; SIAH2; IRF8; SMARCB1; EYA1; RCOR3; PPARGC1A; ZNF160; PAX5; VDR; HOXB6; CITED2; ZKSCAN1; MEOX2; CEBPB; STAT3