Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID50100	Dantrolene	GSE92742	HA1E	Human	6h	10uM	EID0247

Response Information :

Types	Number	Response transcription factors
Up-regulation	355	ADRB2; TCFL5; KDM5A; SSBP2; ZNF701; SOX3; GATA2; TFAP2B; KLF4; SIX3; CSDC2; TBP; CREM; SSX1; ZNF331; CEBPD; ZIM2; WWP1; NEUROD1; NFKBIB; SSBP3; FOXE1; SKIL; NR1H4; ZNF200; BNC1; BARX2; ZNF432; NR1H2; HR; ZNF225; NR5A1; PAX9; PITX2; IRF5; MLLT1; NKX2-1; BRPF1; ANKRD1; PIR; ZNF692; TCF21; EMX2; FOXJ1; EYA3; KLF3; SOX18; ERG; MAK; TFE3; EGR4; SOX21; NR4A1; DNAJC1; ZNF682; OVOL1; RARA; ZBTB25; ZFY; PROP1; ZBTB44; POU1F1; HOXC5; SOX13; ZNF764; POU2F3; ZBTB24; ZNF93; NEUROG3; ARID3B; ZNF695; SMARCA1; PRDM5; GATA1; SIM1; LIN28A; KAT6A; ZNF157; ASCL3; CAPN15; FHL5; CUX2; BRWD1; SND1; SKI; ASCL2; KMT2D; STAT2; MAFB; ETV7; NKX2-8; PAX4; NCOA3; ZBTB7C; EVX1; OSR2; FOXB1; ZNF391; AFF1; VGLL1; ZNF160; LIMD1; CHD2; GATA6; SIX5; UTF1; PITX1; NR2F1; AGO2; ZNF440; NANOG; LHX3; GFI1B; NFX1; PEG3; KLF8; ZNF205; CBX2; NFE2; GLI2; GBX1; TAF7L; EGR3; SAP130; HIC2; ZNF350; WNT4; SCRT1; ZNF281; TFAP2C; TDRD3; POU5F1B; PAWR; BACH1; E4F1; ZNF234; ZFP36L2; ZNF226; FOSL2; ZNF835; ZNF528; ZNF721; NRBF2; ZNF665; EGR2; ZNF180; BCL11B; ZNF80; ZNF674; ZNF223; TRIM22; HIC1; ZNF571; RFX1; MYBL2; ZBTB3; ZNF337; TMF1; FOXD3; MNX1; RORA; MAFG; CTBP2; TONSL; POU2F2; PRDM14; ONECUT2; CBX7; ZNF623; ZNF780B; TAF12; MED12; SAP30; PRDM16; ZNF710; KMT2A; ZKSCAN4; TRIP11; ZNF155; CITED2; ASH2L; EHMT1; ZNF79; VGLL4; RUNX3; BRDT; ZNF611; TRIM33; KDM5C; NACA2; PAX8; TBX1; ZNF263; GABPB1; GCM1; IL16; AR; ZNF778; POU6F1; PIAS2; FOXH1; ZNF480; ZNF85; ING2; MAP3K10; PIAS3; LDB1; MITF; PPP1R13L; WHSC1L1; NR5A2; PLAGL1; GCM2; HDAC5; ZNF224; ZNF35; HNF1B; ZNF688; THAP1; PRDM1; KLF12; WDHD1; STAT4; CREBZF; ZNF771; DNMT3B; ZNF587; ECD; ZNF257; PML; CREB3L2; RBPMS; POLR2A; MAF; IKZF2; CENPF; RYBP; HOXB9; YBX2; ZNF492; ZNF460; ZNF227; NFE2L2; ZSCAN16; FOXL2; ZNF142; FOXN3; PRMT2; CALR; HSF4; PREB; PKNOX1; NFE2L3; NCOA1; ZNF552; EPAS1; TOPORS; HLX; ZSCAN9; CREB3; ZNF813; SNAPC4; MYBL1; AFF2; ZNF222; TBX2; CARHSP1; GFI1; NR4A3; MYT1L; ING1; FOXJ3; TCF7; SPDEF; RERE; GATA4; DDX54; ZNF672; ZNF273; IRF3; ZNF768; SMAD7; SUPT5H; IRX5; CIITA; BCOR; ZBTB39; CBFA2T3; JUP; BAZ2B; FOXO1; POU2AF1; DYRK1B; HLF; ZNF141; RFX2; ZNF236; FOXJ2; HOXD1; PBXIP1; ZNF430; MBD2; ZNF75D; ZNF208; GATA3; TRIM25; RSF1; BRCA1; ZNF329; CIR1; VDR; CHD3; IRF1; RARG; HOXC6; WT1; ZEB2; ZNF202; ERBB4; GRHL2; BNC2; AFF4; CASZ1; HHEX; CEBPZ; PBX2; TSC22D3; CREBL2; KLF5; DAXX; BHLHE41; TULP4; FOXG1; ZIC3; ZBTB16; KAT6B; CALCOCO1; IRF6; MTF2; CTNNB1; CBX6; SMAD3; MYCN; IRF4; CREG1; MNDA; KDM5D; HMGN3; EYA1; AHR; HDAC9; ETS2; CREB1; BASP1; TSC22D1
Down-regulation	454	HOXA5; NRIP1; SCAND1; RNF4; TLE1; ABL1; LOXL2; NR2F6; RHOA; ATF1; ATF6; RB1; HDAC2; GTF2A2; RFX5; ITGB3BP; ZNF589; GTF2IRD1; ATF5; ILF2; THAP11; CDK2; GMNN; NFKBIA; RUVBL1; NKRF; DEAF1; DNAJC2; EDF1; DEK; SUB1; TRIP6; PMF1; RBM39; TSG101; C1QBP; MED21; RFC1; RFXANK; AIP; ETS1; MGA; MAZ; CCNH; KDM2A; TAF10; RAD21; CNBP; WIZ; CTCF; CRY1; MYC; ATF2; SMARCA4; USP22; PCGF1; PTTG1; PATZ1; HBP1; TCF12; SALL2; TFDP1; NELFB; ZNF593; TAF9; SNW1; RBBP8; CDC5L; PHF2; MED27; PHF1; COPS5; HOXA10; SERTAD2; IKBKAP; HDAC3; FOXO3; ZNF146; MED23; CCDC59; HOXA4; ZNF250; SP2; GCFC2; EED; CCNA2; NFYC; PEX2; ATF4; ARID4A; SP140L; COPS2; CBX5; THAP4; CHD1; CBFB; NR2C1; GMEB2; CDYL; DNMT1; MXI1; SUPT4H1; CTR9; CTBP1; ASXL1; DPF2; ERCC2; ZNF148; ERCC3; CHD7; RLF; CNOT2; RELA; HOXA7; ZNF195; RAN; ZBTB11; MED13; RBFOX2; SOX12; TCERG1; TAF6; ZMYM2; ZNF131; ZNF217; SNIP1; REPIN1; THRAP3; CDK8; BTF3; TFCP2; ID1; ARID5A; NOC2L; UBE2L3; MYCBP; SP100; HMGXB4; WDR77; BIRC2; SMARCD1; NCOA6; ELF1; ZNF562; USP21; VPS72; DLX2; SREBF2; ZFP64; URI1; RNF138; ZFHX4; CARM1; GTF3A; MDFI; PHF20; CNOT1; CCNC; TAF11; RNF6; BRD4; BRD8; HNRNPD; MEIS1; PDLIM1; ZNF580; CAMTA1; KAT8; HDAC4; ZNF668; TRIB3; TUB; PTRF; ZNF24; BRD2; MAML1; SPEN; APEX1; RBL2; ZBTB1; FOXF1; ZNF22; CDX2; WWTR1; RELB; ZNF302; ZNF783; ZNF444; FLI1; HLTF; WWC1; BCL3; LITAF; TFAM; ZNF266; HSBP1; ZNF143; ZNF426; MNAT1; NEDD8; MYT1; CBFA2T2; TDP2; BAZ1B; SF1; FUBP1; MLX; SMAD2; RNF2; TBPL1; THAP3; MSX1; SSRP1; SP3; ARL2BP; ZKSCAN5; ARID5B; ZBTB38; XRCC6; PMS1; RNF10; RBBP4; TCF3; HOXD10; CENPB; SIX6; NAB1; BTAF1; HABP4; HMGB1; SATB2; TGIF1; CNOT6; RREB1; ERF; BCLAF1; TGFB1; RUVBL2; HOXD9; BAZ2A; TBX10; ID3; HIF3A; HIRA; VEZF1; NFKB2; ZNF408; TSHZ2; C1D; MLLT10; BRD3; ID2; PBX1; MED16; CDK9; NCOA2; NSD1; TP53; HDAC1; HOXB3; HDGF; MED4; YAF2; TOX4; TCF25; REST; HOXA11; SRCAP; PRDM4; BATF3; ZHX3; ZNF232; MZF1; WHSC1; ZBTB7A; SFPQ; CBX3; ZNF629; KAT5; ZNF189; MYOG; ZNF140; RUNX1; BCL10; ACTL6B; TCF4; TRIP4; TOB1; EZH2; KAT2A; CERS6; ADNP; DR1; ZZZ3; ARNT2; BMI1; HOXB2; HMGXB3; SOX9; IRF9; UBE3A; ZNF16; ELK3; SHOX2; ZEB1; CITED1; ZIC1; HAND1; SAP18; SMARCD3; ZNF268; TGS1; EHMT2; ABT1; MXD3; RNF14; ZFHX3; ZFP36L1; POU3F2; ZNF394; LMCD1; BHLHE40; UIMC1; PCGF2; MTF1; GATAD2A; ETV4; BCL6; TGIF2; MEF2C; SREBF1; HINFP; SMARCC2; KMT5A; HOXB13; ING3; ZNF7; UBE2I; SETD2; RXRB; ZFX; ARID4B; HES1; ARNTL; MNT; NFKB1; ISL1; NRF1; POLR3F; TTF1; ZSCAN12; CHD9; TERF2; MTDH; LEF1; BLM; ZBED1; CCNE1; ZMYND8; ZNF32; NCOR1; SUPT3H; JUND; SALL1; PSPC1; ZNF12; ZNF512B; DMTF1; TRIM27; TRIM29; ZNF45; MEIS2; SFMBT1; TRRAP; ARNTL2; ZNF516; MED24; SOX10; NFIB; TCEB2; FOS; KLF7; TAL1; PSIP1; FOXM1; TLE2; KAT7; STAT6; DDIT3; FOXF2; CREB5; POU2F1; E2F6; SIX1; MEOX1; GLI3; HIVEP1; MECP2; YWHAB; HEY1; ELF2; ETV5; HEY2; JUNB; ZMYND11; HIPK1; ZBED4; ZNF184; RRN3; YBX3; UBP1; NKX3-1; HMGA1; STAT3; HSF2; CBX4; YBX1; SMARCB1; TCF7L2; MDM4; NR1D2; PBX3; DACH1; NFIC; ZNF354A; HIPK3; ZSCAN31; PSMC3IP; TGFB1I1; ZBTB18; ZKSCAN1; FLNA; ZBTB20; IRF8; GTF2I; ST18; REL; PPARGC1A; DLX5; FOXD1; FOSB; TRIM16; TERF1; E2F8; TP63; BCL11A; NR1H3; ASCL1; MEOX2; MYRF; SOX11; CEBPB; ESR1; NR3C1