Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID50095	Cyclosporin-a	GSE92742	HA1E	Human	6h	10uM	EID0247

Response Information :

Types	Number	Response transcription factors
Up-regulation	338	ADRB2; NEUROD1; KDM5A; SSBP2; ZFPM2; GATA2; ZNF331; CREM; WWP1; KLF4; SKI; ZNF623; SOX13; REST; ZNF701; FOSL2; ELF3; ZFY; KLF3; ZNF135; TFCP2L1; NR1H2; RARA; ZNF432; ZNF131; CEBPD; EMX2; MYCL; HLX; SSX1; BNC1; BAZ2B; ZBTB20; MXD1; NCOA1; NRBF2; SOX18; BRWD1; PRDM1; PEG3; ZNF34; STAT5A; ZNF571; TMF1; ORC2; EGR2; HNF4G; CDK8; ZNF22; ZNF226; MLXIP; CAPN15; ZNF696; RORA; ZNF764; MAFB; ZNF813; FOXJ2; ZEB2; JUP; NR5A2; THAP10; ZNF236; LIMD1; ZNF695; ANKRD1; BACH1; SMARCA2; TAF7L; ZNF148; ZNF835; PAX4; AHR; FOXE1; ARNT; TBP; ZIM2; AFF4; ZNF614; CHD2; TCF21; ZNF710; HES1; KDM5D; ZNF350; NR3C2; SUPT5H; ZNF391; FHL5; IRF5; ERG; MITF; ZNF248; PLAG1; SOX17; HMG20A; ZNF225; AFF1; ZKSCAN8; ZNF157; ZNF507; ZBTB3; ZNF688; ZNF692; POU1F1; SND1; ZNF492; ZFP37; ZNF573; NANOG; RSF1; ZNF528; MNX1; OVOL1; MAF; PLAGL1; ZFP36L2; HIC2; BCL11B; ZNF343; USF2; ZNF674; TFAP2B; CSDC2; SP1; SUV39H2; BCOR; ZNF160; ZNF205; ZBTB43; TBX4; CUX2; CDX1; ZKSCAN4; ZNF180; MAX; SSBP3; HCFC2; ZNF550; BTG1; CDIP1; NKX2-1; OLIG2; NKX2-2; IKZF2; NFE2L2; ZNF85; ZSCAN16; ZNF480; ZNF442; ZNF112; ZNF250; BHLHE41; WT1; CARF; TRIP11; NR1H4; BAZ2A; HOXD1; SP4; KLF11; RBM14; SKIL; CEBPG; HR; ZNF516; ZNF304; TBR1; OSR2; FOXA1; NFIL3; POU2F3; ZNF234; ZNF227; ZNF224; ZNF557; EP300; E4F1; PROP1; ZNF780B; HDAC6; IRX5; ZNF253; STAT2; HTATIP2; GCM2; FOXI1; PGR; UBTF; WHSC1L1; ZBTB39; HDAC7; ZNF362; SAP130; BRDT; ZFP30; ZNF223; ZBTB44; TRIM22; NCOA3; CBFA2T3; ZNF440; CHAF1B; TRPS1; CAMTA2; FOXN2; ZNF329; ZNF214; TOPORS; TXNIP; ZNF80; NFYC; IKZF3; TBX1; MKL2; ZNF682; L3MBTL1; ZBTB25; ERBB4; TWIST1; ZNF551; BRPF1; SIM1; ZNF721; POLR2A; NSD1; MYF6; MYC; ESR1; HSF1; ZNF217; CHD3; DNMT3B; PRDM10; TRIM28; XBP1; ZNF44; KMT2B; PITX1; HOXA11; NR2F1; PRKDC; ECD; YBX2; PPARA; ZKSCAN7; ZNF665; ING4; RFX7; TAF4; ZNF212; MSC; CREBZF; PIAS3; KMT2D; ZNF12; ING2; MYT1L; SFMBT1; PIR; TRIM33; PLAGL2; LEF1; IRF6; KLF6; MNDA; ZNF10; ZNF273; MBD2; SMARCE1; DDX54; ZNF254; MED15; ZNF430; PAWR; DNAJC1; TRIM32; ZFP36L1; ADNP2; EGR4; INSR; NFYA; TSC22D3; EN2; KLF5; BRD2; ZNF529; OVOL2; BRCA1; TCF7; ZNF83; GATA3; NLK; ZNF141; ZNF611; TEAD4; HIPK2; ATF7IP; ZNF552; HOXD3; KAT2B; AR; KAT7; CLOCK; ZNF93; LIN28A; NR4A1; TFAP2C; CD3D; ELF4; PPARD; GRHL2; CTNNB1; ARRB1; EGR3; SAP30; NFAT5; KAT6B; KLF10; ZNF654; RCOR1; BNC2; BBX; HLF; IRF1; NFE2; KLF9; AEBP1; FOXJ1; TFEC; TOX3; ZNF264; TFDP2; HDAC9; NFE2L3; HMGB3; RBPMS; ETS2
Down-regulation	434	SCAND1; HOXA5; LOXL2; CDK2; ABL1; ATF1; NR2F6; RFX5; HDAC2; DEK; RUVBL1; ZNF589; NFKBIA; ATF6; PTTG1; GTF2IRD1; RNF4; ITGB3BP; GMNN; RBM39; CENPF; CCNH; TAF10; THAP11; CARM1; TAF9; C1QBP; CBFB; ETS1; ATF5; DEAF1; SUB1; RBFOX2; ILF2; ID3; SERTAD2; RFXANK; TSG101; PHF1; CBX5; SUPT4H1; ATF4; SUV39H1; UBE2L3; PRRX2; HDAC3; CDC5L; CCDC59; IKBKAP; MAZ; ZNF232; VPS72; TAF6; HOXA4; THAP4; HIVEP3; DNMT1; COPS5; FOXO3; CREB3; SMARCA4; ZFHX4; BCLAF1; APEX1; ARNT2; REXO4; STAT6; ZZZ3; RBBP4; COPS2; ZNF576; WIZ; USP16; ZNF24; GTF3A; HOXB6; MYCBP; RUVBL2; MED27; SMARCD1; NKRF; DLX2; PATZ1; NOC2L; NFRKB; TRIP6; CTBP1; XRCC6; FUBP1; CSDE1; RING1; LITAF; USP21; MED13; BIRC2; TCF25; BTAF1; PCGF1; ZBTB17; HOXB3; FOXF1; BTF3; ID1; HOXC6; TADA3; ZFHX3; THRAP3; TLE4; HAND1; NPAS1; PCGF3; SF1; HDAC4; AIP; PBX1; KDM2A; VEZF1; MSX1; PSMC3; WDR77; PMF1; CRX; ELF1; HOXD10; VSX1; ZBTB40; VGLL4; SP140L; RFXAP; LHX1; LMCD1; TCF3; TDP2; HOXA7; PSMC3IP; TUB; MGA; ZNF140; ATN1; CHD1; ABT1; PDLIM1; NCOA6; RFC1; FOXJ3; CEBPE; ACTL6B; KMT5A; SPEN; ZNF263; ACTL6A; MED21; SMAD7; ARID5B; IRF3; PFDN5; TBX10; DLX6; JUN; TBPL1; SNAI2; ERF; ZNF593; SP140; FOXP3; HMGXB3; ZNF446; VAX2; HOXA6; SAP18; PAX5; ID2; ZNF76; SIX5; SHOX2; MTF2; BASP1; TRIB3; CCNC; CTR9; ZBTB11; CBFA2T2; HDAC1; PEX2; HNRNPD; WWC1; GBX2; ZNF266; CENPB; CBX3; CAMTA1; WHSC1; DNAJC2; MYNN; ZMYM2; ETV4; ZMIZ1; MLX; FLNA; PTRF; TCF4; RBBP8; TOX4; PITX3; MDFI; MED20; ENY2; MAPK8IP1; TERF2; BAZ1B; FOXF2; TBX6; ZNF562; THAP3; CREB5; MBD3; ZNF408; ISL1; SUPT6H; MYOG; ZKSCAN5; IRF2; TFCP2; SRCAP; RXRG; CITED1; TBL1XR1; SMAD2; ATF2; NEDD8; ASXL1; CNBP; ZBED1; ZNF426; PMS1; ALX1; RBPJL; TAF9B; RNF10; ZNF444; SOX10; HIRA; RBBP7; HOXB5; ZSCAN2; HMBOX1; ZBTB1; ZFP64; MTDH; CERS4; HLTF; HOXB1; NR2F2; BPTF; ESR2; KDM5C; BATF3; TRIM27; ZBTB7A; MNAT1; BCL11A; NFKB2; EHMT2; HOXB2; PREB; HSBP1; SIX1; SCMH1; SMAD3; HMGB2; PSPC1; MECP2; RNF2; HHEX; HEY1; FLI1; TAF1A; TP53; MXD3; NFKB1; NAB2; ZEB1; ZNF544; TAF7; CEBPB; POU3F2; E2F3; RORC; UBE2I; HOXC8; PAXBP1; IRF9; PARP1; LMO1; NCOR2; DPF2; HOXB7; ARID4B; DAXX; SSRP1; TGIF2; RUNX1; PURA; CDYL; ATF6B; SOX9; POU2F2; MEOX1; SP110; CNOT2; FOS; PHF8; POU2F1; FOXN3; ZNF652; DMTF1; KAT8; SREBF2; PHF20; MZF1; YEATS2; HOXD9; NELFB; RNF14; TGFB1; DR1; YBX1; HIPK1; TRIM16; EWSR1; MBD1; HINFP; BCL3; MED6; MED4; SP3; WWTR1; HOXC10; SALL2; RREB1; ERCC3; MXI1; MED17; BACH2; ZNF302; ZNF668; NFE2L1; ZNF177; DLX5; BRF2; ZNF580; THAP7; CEBPZ; SMAD4; CHD7; BMI1; FOXO1; SOX11; TBL1X; PRPF6; SALL1; ID4; ZNF195; TOB1; NHLH2; FOXD1; E2F6; PSIP1; HOXC4; ZBTB18; MTA1; C1D; NONO; ZNF268; JUND; SIX2; NKX3-2; MYRF; HMGB1; TFAM; EN1; TRRAP; BCL6; DDIT3; TRIM29; INSM1; RXRA; MEN1; ZNF146; SMARCB1; JUNB; ZNF512B; E2F5; FOSB; TLE2; ZNF202; RNF138; BRD3; IRF8; KMT2A; CHD9; SMAD6; SUPT3H; ARID1A; TAF11; HDGF; SP100; UBP1; TCEA1; ZBTB38; ATF3; SPIB; PBX3; CEBPA; IRF7; ZMYND8; ZNF189; TCF7L2; ZNF532; SIM2; ZNF91; SMARCD3; MEOX2; TBX3; NR1H3; CREBL2; STAT3; ST18; STAT1; ZKSCAN1; EYA1; TBX2; SOX2; ZNF586