Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID50093	Cirazoline	GSE92742	HA1E	Human	6h	10uM	EID0247

Response Information :

Types	Number	Response transcription factors
Up-regulation	421	ADRB2; PPARG; ZNF701; ZFY; WWP1; KLF3; CREM; SSBP2; KLF4; BRWD1; ZFPM2; ZBTB20; MEF2C; SUV39H2; E2F2; GATA2; ZNF695; ZNF331; NFX1; FOXD3; ZNF835; GFI1B; HNF4G; ZNF225; NR5A2; EGR2; ZNF623; ZBTB6; ZNF227; ZBTB7C; ZNF813; CEBPD; HIC2; TWIST1; ZBED2; STAT5A; PAX4; ARNT; NEUROD1; ZNF432; DOT1L; NR1H4; VGLL1; ELF3; LIMD1; OVOL1; ZNF334; ZNF135; SOX13; CSDC2; NFATC1; ZNF180; AFF4; IKZF2; ZNF214; ZNF571; SOX18; ZNF407; ZBTB3; TBX1; SSX1; POU1F1; ZIM2; ZNF550; ZNF674; LPIN2; HLF; TAF7L; ZXDC; STAT2; ZNF80; PKNOX1; NR1H2; ZNF223; ZNF157; ZNF764; TBP; ZNF573; PEG3; THRB; BRIP1; RSF1; PLAGL1; ZNF391; ZNF682; KLF8; ZNF112; FOXL2; SKI; SP1; WNT4; NKX2-1; CAPN15; ZBTB24; HIC1; FOXK2; ZNF132; ZNF780B; IKZF3; ZNF41; NFYA; ZNF629; GCM2; TEF; RORA; RFX7; NRBF2; ZNF236; IRF4; ZKSCAN4; FOXE1; NFYC; SCRT1; ZNF492; HDAC5; RFX1; ZNF711; HDAC6; CHD2; PIAS1; AFF1; EGR3; SOX21; ASCL2; NLK; ZNF141; GATA6; NCOA2; POU2F3; PML; TBX21; PITX1; ZNF350; MAK; MYCL; ZNF107; KDM5D; REST; NANOG; SOX3; ING4; PIR; ZKSCAN8; TFCP2L1; NPAT; ZNF215; SIRT7; PLAG1; TBR1; BNC1; BLZF1; ZBTB44; ZNF257; ZNF200; ZNF549; NCOA1; ZNF442; ZNF771; RARA; ATF7IP; TRIM33; RBL1; CREBZF; ZNF34; ZFP30; PPP1R13L; SND1; EMX2; NFE2L3; MLLT1; BCOR; POU3F1; NEUROG3; RUNX3; ZNF292; FOSL2; LIN28A; L3MBTL1; SMARCA2; MAFF; CBX8; ZFP37; BCL11B; ZNF688; ZNF81; CTNNB1; MAF; ZNF234; ARRB1; SAP130; ELK4; CIITA; ZNF551; ZNF696; SKIL; ZNF226; IRF1; PNRC1; EMX1; KLF11; ASCL3; ZNF304; ETV6; ZNF480; GRHL2; ZNF440; ZNF264; TFAP2B; UBE2B; MXD1; MSC; NR2F1; RREB1; ZNF749; TTF2; ZNF154; MYT1L; THAP9; DDX17; FOXC2; SP4; YAP1; ZNF528; MYBL1; KLF12; ZNF274; ETV2; TLX3; ZNF814; ZBTB25; PRDM10; TSC22D2; SRY; CUX2; SSX7; ZNF665; PAWR; BACH2; ZNF329; ZNF506; GCFC2; WT1; TP73; PITX2; TDRD3; AGO2; ZNF239; ZNF507; FOXJ1; KAT6A; GBX1; NR1H3; KMT2D; CAMTA2; ZNF165; RBM14; NFE2L2; RFX3; CDIP1; AHR; ZNF75D; GCM1; ZBTB14; HBP1; TRIM28; HSF4; CBFA2T3; ZNF721; ZNF273; FOXB1; ZNF816; ZNF471; ZNF142; ZNF614; MYEF2; TSC22D1; BNC2; PROP1; ADNP; SIM1; MED31; NR4A1; NCOA3; THAP10; ATOH1; CLOCK; MITF; MED12; E4F1; ZNF160; VGLL4; TAF6L; ZNF267; GATA1; ZNF611; PBXIP1; MXI1; HIPK1; TRIP11; HESX1; POU6F1; ZNF710; EPAS1; MED14; SMAD2; ZSCAN16; OSR2; BHLHE41; ZKSCAN7; OLIG2; SOX17; ALX1; ASH1L; BACH1; TEAD1; SIX3; BCL10; BARX2; HLX; ZNF692; MAFB; NR3C2; TOPORS; ATF7; NR4A3; POU4F2; SCAI; KLF5; HIPK3; CD3D; TGIF1; ZNF205; ZNF254; SP2; PRKDC; ZNF93; EGR4; CITED2; ZNF675; TGS1; TXNIP; RERE; KLF10; TMF1; PLAGL2; ZNF460; IFI16; KLF6; SMARCA1; SMARCA5; LZTS1; CIR1; ZNF516; SSBP3; ZHX2; ZIC3; JAK2; TRIM22; CIC; ZSCAN31; TCF20; ZNF85; POU5F1B; RFX2; ZNF117; ZNF10; YBX3; TOX3; CALCOCO1; RBPMS; OVOL2; REL; GATA3; DNMT3B; EHF; SAP30; SUPT5H; CARHSP1; ZNF208; ZNF552; SATB1; PRDM13; TCF7; TCF21; GFI1; ZNF83; ZNF468; PHIP; MNT; CALR; MED7; ZFP69B; KAT2B; FOXJ2; RBBP5; ZNF532; PRDM14; YBX2; MBD4; RCOR3; ZEB2; HMGN3; MBD2; TCF7L2; PCGF2; LEF1; MAFG; MYCN; IRF8; SPIB; CREBL2; TFDP2; EN1; TRPS1; INSR; MNDA; NR4A2; AEBP1; ZBTB16; KLF9; TBX2
Down-regulation	443	SCAND1; HOXA5; DRAP1; LOXL2; NRIP1; TLE1; ABL1; CDK2; NR2F6; PSMD9; DNAJC2; RUVBL1; ATF6; ATF1; GTF2A2; MAZ; ZNF589; ITGB3BP; DEK; ATF5; NKRF; GMNN; AES; RFX5; TCEA2; CCNH; SNW1; EDF1; GTF3A; SF1; PCGF1; DNMT1; AIP; ENY2; CBX3; CARM1; ZNF580; TADA3; PTTG1; NPM1; RNF4; MYC; ZNF593; GTF2IRD1; CBFB; CENPF; RNF10; NELFB; TAF9; IKBKAP; RBM39; APEX1; PA2G4; FOXO3; RBBP8; BTF3; CCNA2; RFXANK; MED27; CCDC59; SMARCD1; WIZ; CDC5L; ATF4; HNRNPD; DEAF1; SMARCC2; ZNF146; C1QBP; BRD4; ARNT2; HOXA10; THAP4; HMGB1; ZNF140; SUB1; TULP3; TDP2; NFRKB; ELF4; PATZ1; APBB1; CENPB; VEZF1; SUPT6H; HOXA7; ZNF408; FLNA; WDR77; ERCC3; TAF10; MED21; HOXB5; TRIP4; SMAD7; VPS72; PBX3; PBX1; DLX2; RAN; KMT5A; HOXB6; XBP1; MSX1; ZNF24; PCGF3; ARL2BP; FOXF1; SIN3B; JUND; SP110; USP16; USP21; FOXJ3; ZNF131; COPS2; MTF2; BIRC2; CTCF; NFYB; SATB2; PRRX2; ID3; ZBTB40; ARID4A; POLR3F; TBX10; HOXB3; COPS5; TRIB3; PDLIM1; HOXA4; TOX4; FOXP3; ZFP64; MTDH; MLX; PMS1; MAML1; ZZZ3; ZBTB17; TCF3; CCNC; DLX6; NFKB1; WWC1; ZMIZ1; ZFHX3; BRF2; RBBP7; SREBF2; PRDM4; BAZ1B; ID1; GTF2A1; CCNE1; CHD4; ZNF148; MGA; HDAC3; ZNF536; PHF1; C1D; ZFHX4; SALL1; DPF2; SP100; XRCC6; RNF6; MED6; BRD8; ZNF446; HSBP1; TERF2; GATAD2A; ZNF444; ERBB2; NPAS1; CEBPE; TAF7; PMF1; HLTF; ZNF646; SP140L; PTRF; ZMYM2; ARID5B; SMARCD2; ZBTB38; VSX1; HOXB2; TAF6; GBX2; ZNF276; ZBTB7A; TCF4; ZBTB11; DR1; NCOA6; IRF3; TSG101; CHD8; TUB; HOXD1; ASH2L; SERTAD2; CREB5; CRY1; VAX2; MNAT1; BRD7; ZNF84; CDK9; ZNF3; MED13; TAF5L; DAXX; SPEN; BCLAF1; KDM2A; TFAM; ZNF12; DNAJC1; GMEB2; NOC2L; TLE4; HOXA6; SRCAP; TRIM27; ZNF512B; TBL1X; PHF2; MEOX1; MYNN; ZNF562; HMGXB3; ID2; BCL3; ETV4; KDM5C; MED20; REPIN1; CEBPZ; SMARCB1; NCOA4; ING3; NACA; PHF8; YWHAB; RBFOX2; SMAD3; SAFB2; TCF25; POU2F2; ZNF263; HABP4; SHOX2; SIX1; SIRT2; NCOR2; BRD2; UBP1; CHD3; HMX1; MXD4; MED16; ZNF668; SAP18; NR2C1; MYOG; MZF1; BHLHE40; PSPC1; ZNF652; ZNF335; ELF1; UIMC1; MXD3; FUBP1; LITAF; RUVBL2; ZHX3; FOXM1; EGR1; CREB3; LDB1; NFE2L1; SMAD1; SSRP1; POU3F2; TCEA1; ZKSCAN5; HIRA; ELK3; SP140; TRIM32; TBX6; TRIM16; MED25; ARID4B; BANP; NR2F2; ZNF268; STAT6; ZBTB1; NHLH2; MED4; PSMC3IP; FOS; WWTR1; SMARCE1; CITED1; BAZ2A; PAXBP1; HAND1; ZNF212; MED24; YEATS2; CHD1; HOXB9; FOXF2; BMI1; ZSCAN2; MAX; PIAS3; DDIT3; PQBP1; CNBP; RELA; HOXD10; CREG1; ATF2; ABT1; DMTF1; ZMIZ2; ZKSCAN3; CTBP1; CBX5; PAX5; ARNTL2; EHMT2; ZEB1; CTR9; NONO; E2F3; BRD3; HMGXB4; ZNF266; HOXA11; RNF138; RBL2; YAF2; CIZ1; BLM; POU2F1; SIM2; DLX5; RRN3; CEBPG; ZSCAN32; RBPJ; HOXD9; TGIF2; SFPQ; BASP1; TCF15; SNAPC4; CASZ1; MEIS1; TOB1; SUMO1; STAT1; MDFI; RFC1; HOXB7; ZBTB43; CUX1; USF2; NFIB; RNF14; SREBF1; ZNF768; ZFX; IRF9; RYBP; ACTL6A; LMCD1; DACH1; CRYM; PRMT2; HMBOX1; FOXC1; PSIP1; PEX2; TAF11; HDAC1; ZNF354A; ETV5; ZIC1; ZKSCAN1; ZNF177; TRIP6; HIVEP1; KLF7; KAT6B; ZBTB18; TEAD4; ZNF189; ESR1; SUPT3H; NEDD8; PHF20; MECP2; TRRAP; CRK; ERG; NFIC; TP63; VDR; ARID1A; HDAC9; SNAI2; PBX2; HDGF; FOXD1; HOXC6; ATF3; KLF2; NKX3-1; CEBPB; CREB1; RBBP4; TLE2; SOX9; NR1D2; BBX; STAT3; MAGED1; SOX11; HOXC10; ID4; SOX2; NR3C1