Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID49700	Orphenadrine	GSE92742	HA1E	Human	24h	10uM	EID0245

Response Information :

Types	Number	Response transcription factors
Up-regulation	124	ZNF274; TFEC; NFE2L1; ZFP69B; ZNF141; NFE2L2; ZNF214; SSBP2; SOX17; ZNF551; WT1; TCEA2; FOXN3; ILF2; ZNF695; EN1; FOSL2; ZNF350; ZNF33B; TRIB3; SCAI; ZNF268; INSR; VPS72; KLF11; HLF; TEAD4; ZNF180; ZNF44; ZNF544; POU1F1; APEX1; ZNF426; AHR; L3MBTL1; GATA6; TAF1A; ZNF136; HLX; IFI16; WWC1; SOX18; ZNF254; BCL11A; ZNF492; ZMIZ1; BNC2; ARNT2; ZNF165; ZNF571; SOX3; EMX2; ZNF107; BACH1; ZFPM2; HSF1; ZNF91; MAK; CERS6; TMF1; SOX13; POU2AF1; PAWR; MNDA; THAP10; TLE4; ZEB1; ZNF329; TCF21; ZNF682; NEUROD1; ZNF512B; ZNF257; NANOG; POLR3C; ZNF573; PHIP; RAD21; NR5A2; KAT2B; ZNF331; ZNF83; NR1H2; MYCL; TAF11; E2F8; PBX3; ZNF334; HBP1; SKIL; ZNF423; PBXIP1; HIC2; TGFB1; IRF9; ZNF468; ST18; MEIS2; ZNF43; BHLHE41; ERG; ZNF217; MYBL1; MYCN; CTBP1; SNAI2; MECOM; PITX1; ZNF304; ZBED2; ATF3; PEG3; ZFP36L2; INSM1; LIN28A; TBX2; TBX3; TWIST1; TFAP2C; MED24; NFE2L3; LEF1; MEIS1; MXI1
Down-regulation	154	ZNF589; ELK1; ORC2; PSMD9; RELB; STAT6; KLF15; UIMC1; MED27; PRRX2; ZMIZ2; ING1; ZBTB38; CHD3; FOXC1; ID2; NFKBIB; MAP3K10; RNF141; ZFP64; HLTF; NFIL3; ZNF282; CNOT1; CITED1; TSC22D4; TRIP6; GATAD2A; LITAF; HOXC6; STAT3; DR1; HOXC10; PHF8; TBP; BATF; NEDD8; BHLHE40; SIAH2; SETD3; NCOA6; PPARGC1A; SOX9; CBFA2T2; KMT2A; RNF14; BRD2; HDAC1; PIAS2; NPAT; ZNF384; TRIM25; BAZ1A; CCNT1; BRD8; RBBP7; JARID2; ZMYND11; BCL3; NR1H3; ZBTB40; HOXB9; SMAD5; NAB1; YBX1; RARA; SIN3B; KDM5D; HMGA1; TGIF1; MEOX1; SFMBT1; FOSB; RELA; DDX5; ENY2; CBFB; ABL1; SMARCE1; EDF1; FOSL1; TRIM16; BLM; SMAD2; SPEN; HSBP1; RBPMS; SERTAD2; LPIN2; GTF2I; KLF9; MAML1; ZNF672; PURA; BASP1; BATF3; NFAT5; SMARCA1; CREB5; ID4; HDAC7; DLX2; BBX; POLR2A; CHD1; ELF1; RBL2; YAF2; SIX1; MED13; ENO1; STAT1; NFKB1; TSC22D3; KLF10; DMTF1; HMGB3; RBBP4; CEBPA; HMGA2; RXRA; SAP30; STAT5A; MTF2; BRD4; RUNX1; EYA2; FOXF1; MNAT1; DNMT3B; JUND; BAZ2B; TOB1; ZMYM2; TBL1X; HOXC4; HMGB1; ELF3; TSC22D1; BCL11B; NFATC1; HOXB7; SOX10; NPAS2; PTTG1; DACH1; SREBF1; PCGF2; ATF7IP; JUNB; NR2F2; HES1; GATA3; TCFL5