Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID49524	Tranilast	GSE92742	HA1E	Human	24h	10uM	EID0244

Response Information :

Types	Number	Response transcription factors
Up-regulation	125	IKZF1; SPDEF; NFATC4; NR1H2; KLF13; ZNF74; HIRA; TP73; ZNF665; HOXD1; ZBTB16; JUP; NKX2-1; PRRX1; DNMT1; PRDM14; BACH2; PITX2; MED15; RING1; USP21; SALL2; IRF6; ZNF611; ZNF573; MED17; VGLL1; EPAS1; ZNF224; ATF3; BNC2; BCL11A; KLF3; NR5A2; ZFPM2; ZNF232; TCF7L1; E2F4; KAT2A; BNC1; NEUROD1; ZNF91; SATB1; CBFA2T3; RBFOX2; TP63; CREB3; ATOH1; SMARCB1; ZNF195; PRDM2; MEIS2; SOX2; SNAI2; ZNF623; ERBB4; TRIB3; TULP3; CBX4; CEBPD; POLR3C; RARG; ZNF264; HSF1; ZSCAN9; ZNF22; BRD4; ELF4; HIC2; ARL2BP; INSM1; CNOT3; WT1; ZIC3; ILF2; ARNT2; TWIST1; E2F5; ZNF544; CERS4; NFE2L2; EN1; SPIB; ZNF415; ZNF83; IFI16; FOXA2; IRF3; INSR; FOXA1; VPS72; TDP2; ZNF44; AEBP1; ZNF93; ZFP36L2; ZEB1; ZBED2; ZNF160; ZMIZ1; ST18; FOXF2; GATA6; PAX5; NR4A2; CALR; NR4A3; MAF; ZNF43; TBX3; TFAP2C; PAWR; TGFB1; ID1; KLF4; IRF8; ZNF331; TOX3; TRPS1; NR4A1; TAL1; ID3; CITED2; ZIC1; HOXB2
Down-regulation	192	REST; ATF1; WDHD1; SMARCA4; KAT7; HSF2; RFX5; MTDH; NFYC; ZNF516; KLF12; SIAH2; SNW1; ETS1; CTR9; TRIP6; MSX1; KDM2A; TP53; KDM5A; SP3; CRK; EDF1; USF2; PCGF2; BMI1; IKZF5; TSC22D2; RCOR1; HTATIP2; GABPA; NSD1; SFMBT1; PIAS2; NFE2L1; HNRNPD; ETS2; BRD8; BTAF1; CHD1; TBP; MSC; ZNF146; PHF8; CRY1; RNF141; SETD2; NCOA1; FLNA; ARID4A; TEAD1; FOXO3; KDM5B; TAF10; ECD; NFKBIB; RHOA; ZBTB11; LMCD1; YAF2; NPAT; ZHX3; NR3C1; ELK3; FOXO4; PPARGC1A; RBM14; NCOA6; NEDD8; ZMIZ2; ZEB2; REPIN1; KLF6; EP400; PHF2; MED6; RNF10; ZFP64; BHLHE40; AFF1; DPF2; TMF1; ZNF23; SOX4; BAZ1B; SMARCA2; RELB; HDAC4; TRRAP; CCDC59; TBL1X; BATF3; STAT5B; HOXC6; CREBZF; MXI1; SMARCD2; KAT5; ZBTB43; POLR2A; EGR1; LZTS1; STAT3; NR2F2; TSC22D4; NRF1; NFKB1; WHSC1; NAB1; NRBF2; NCOA4; SFPQ; IRF5; CREG1; BRD3; SETD3; RBBP4; ENO1; ZNF84; BLM; JARID2; YWHAB; ORC2; BRIP1; SAP30; HEY2; ELF1; DNMT3B; KMT2A; CBFB; JUNB; FOXC1; HLTF; ELK1; SIM2; BCLAF1; TBPL1; AATF; ZBTB18; LPIN2; SMAD2; ZMYM2; CBX3; KLF10; ZNF589; KLF2; ASH2L; MED1; BAZ2B; SATB2; SIX1; HOXA11; RBBP8; SUB1; HDAC1; RBBP5; PRKDC; PIR; ELF3; HIPK3; HMGB2; DDIT3; SERTAD2; FOXD1; PURA; MEF2A; STAT5A; EZH2; HDAC6; KDM5D; IRF4; ING3; ISL1; NR1D2; NFIL3; BRD2; TSC22D1; ZNF443; HOXC10; TRIM16; JUND; ZBTB38; POU4F1; XBP1; SAP18; MBD2; BBX; EYA2; ERG; CREB1; TBX2; SUV39H1