Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID48918	Mdm2-inhibitor	GSE92742	HA1E	Human	6h	10uM	EID0242

Response Information :

Types	Number	Response transcription factors
Up-regulation	49	ZNF281; SOX11; RNF141; PRMT2; CDK8; PAXBP1; CDK9; MYB; XBP1; TOX; CUX2; RNF138; HIPK1; SUPT3H; TAF9; TDP2; RXRA; TTF2; RB1; BANP; TCEA1; SAP30; MED4; WHSC1; ZNF141; PIR; ZNF165; ERG; TGFB1I1; RAD21; HEY2; ETS2; CREB1; RBPMS; NFAT5; NCOA2; HIRA; KLF6; SERTAD2; FOXN3; GTF2A2; KLF9; TCF7L2; NKX3-1; TERF1; KLF2; ZNF423; AHR; KDM5D
Down-regulation	68	ZNF586; NFKBIA; ZNF134; IRF3; RFX5; TP53; NR2F6; ZNF587; BRF2; ZNF611; ZNF419; ZNF551; ZNF160; TRIM28; ZNF721; NPM1; CBX7; PAX8; DLX2; ZNF14; HOXB5; ZNF337; NPAS2; ZNF430; ZNF544; ZNF266; ZNF432; ASH2L; ESR1; GTF2IRD1; KAT6A; ZNF652; ZNF468; PREB; TRIM29; FOXO3; NCOR2; HOXA11; HDAC4; TXNIP; EGR3; SSBP3; JUP; SREBF1; HDAC1; STAT6; FOSL2; SMARCA2; MAFF; HOXB2; ZMYND8; SOX17; FOSB; NAB1; CREB3L2; TBX3; DACH1; MLXIP; HOXB6; PURA; JUND; MSX1; LITAF; RELB; TOX3; FLNA; SOX9; HOXC6