Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID48852	Digoxin	GSE92742	HA1E	Human	6h	10uM	EID0242

Response Information :

Types	Number	Response transcription factors
Up-regulation	120	EGR1; SOX11; NFKBIA; RLF; MYC; ATF3; NFE2L2; TXNIP; MYCL; EN2; SIX6; RSF1; VPS72; HMGXB4; FOSL1; PEX14; TTF2; DLX5; NKX3-1; ZNF22; ARID4B; SIAH2; CDK7; JUN; SCMH1; ZNF146; NFKBIB; RRN3; BACH1; NR4A3; ST18; RBPJ; IRF1; RBFOX2; ZNF136; NFKB1; AIP; HDGF; ASXL1; HLX; ZNF331; YBX1; HIPK3; KLF1; MED4; HOXD11; BCL6; HIVEP1; HES1; MEIS2; SERTAD2; HEY1; KLF11; TCF12; PNRC1; IRF9; GABPA; ILF2; KAT6A; EYA2; ZNF83; NR4A2; KLF4; RAD21; TAL1; RELA; NFE2; TFAM; CCNE1; EWSR1; MECOM; PAX6; REL; CREB1; MED17; KLF3; DLX2; RING1; KLF9; SMAD3; SSX1; CHD1; POLR3C; NR4A1; NRIP1; OSR2; YBX3; RBL2; SPEN; BCLAF1; FOXG1; MAFF; HLF; EZH2; BHLHE40; TSC22D1; RELB; NFAT5; HEY2; ZBED2; DEK; MED24; TFEC; TCF7L2; GTF2A2; HOXB2; ZNF467; FOSL2; BRD4; BIRC2; RBBP8; BTG1; ACTL6A; RBPMS; ID4; CD3D; SOX9; TRIB3; PBX3; KLF7
Down-regulation	109	ZNF586; ZNF589; NR2F6; HOXA5; HOXA10; ATF5; TLE1; LIMD1; YWHAB; CENPB; RBBP5; THAP11; NPAS2; PIR; MED7; BRCA1; CRYM; SFPQ; CBX5; TFDP1; SUPT5H; DNMT3B; PAWR; TRAK1; CNOT1; SF1; SIM2; RNF4; ZBTB1; TCF4; XBP1; SMAD2; SMARCC1; ZSCAN31; RFX5; LIN28A; ZNF544; ZBTB20; HOXA11; PAX8; SOX12; TSC22D4; NPM1; ZNF184; HTATIP2; MTA1; HMGA1; NANOG; ZNF281; CTBP1; ZNF268; ETV4; CREB3L1; ZNF329; TBL1XR1; ZNF189; MAFG; CARM1; LITAF; CARHSP1; MAGED1; RAN; MXD4; WWP1; POU5F1B; ZMYND8; ZSCAN16; TULP4; TOX3; DDX5; ZFP64; HOXC6; ZNF84; COPS5; PITX1; AFF1; SLC2A4RG; ZNF532; BANP; ADNP; WWTR1; CTNNB1; PITX2; ESR1; ZNF165; MLXIP; SMAD1; ASCL1; TBX3; JUND; WWC1; CBFB; TRIM28; TOB1; BNC2; CTBP2; MAF; MTDH; HDAC1; HDAC4; BBX; LMCD1; ID3; NR2F1; FLNA; MAFB; CREB3L2; FOS; TCFL5