Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID48338	Cucurbitacin-i	GSE92742	HA1E	Human	6h	10uM	EID0240

Response Information :

Types	Number	Response transcription factors
Up-regulation	135	NFATC3; TSC22D3; FOXO4; SMAD5; NFIL3; JUNB; HTATIP2; XBP1; TEAD1; TWIST1; KLF4; ZNF304; SOX13; BHLHE41; PEG3; CCNE1; TFE3; RXRA; KDM5A; TRIP11; ARRB1; KDM2A; STAT2; ZNF331; SOX5; SAFB; TBX2; MAFB; GATAD2A; TULP4; TFAP2C; DDIT3; ZNF84; PIR; ATF7IP; ATF3; DPF2; RNF141; SF1; KLF9; NFIC; NCOA3; KLF2; OSR2; ZNF148; BRWD1; ZNF274; HIC2; TRIM33; TGFB1; HDAC6; STAT1; MEF2C; NEUROD1; MBD2; FOXO1; GLI3; YEATS2; ZNF415; DNAJC2; NLK; NFAT5; FOXE1; HBP1; IRF9; PHF8; BRD2; TRPS1; CITED2; ELF4; SSX1; MYCN; KLF11; FOXA1; FOXJ1; SOX3; CDK9; EGR2; NR4A2; CEBPB; PKNOX2; TSC22D4; RSF1; AFF4; NCOA1; POU4F1; AFF1; DLX5; SMARCA2; SMAD1; DDX17; ELF5; BRD4; TSC22D1; E2F8; HIPK3; CEBPG; RARA; EGR3; FLNA; EHF; RBPJ; WT1; GRHL2; SNAI2; BARX1; SIX2; HOXB6; HIVEP2; NKX2-2; ZNF91; TBL1X; NR0B1; TRIB3; BBX; TERF1; HOXB2; ZSCAN18; DMTF1; GABPB1; MYB; NAB2; NR1H3; MNDA; NCOR1; MXI1; ASCL1; BTG1; MDM4; EMX2; YBX3; ESR1; KDM5D; TXNIP; THAP11
Down-regulation	100	LOXL2; TRIM16; RFX5; NEDD8; HOXA10; HMGXB3; ZNF446; TADA3; APEX1; DAXX; ZBTB18; RNF14; MNAT1; MED6; ZNF22; IRF8; C1QBP; TFEB; ZNF512B; REPIN1; PHOX2B; NR2F2; POU3F2; SRCAP; SIX3; ZMIZ1; BATF3; BHLHE40; ENY2; BPTF; NFRKB; PRDM12; ZNF580; POU2AF1; LYL1; SMAD3; SLC2A4RG; ZSCAN5A; RARB; PHF1; CDX1; RBBP8; DLX2; HSBP1; VGLL4; TGFB1I1; TRIM22; KLF1; ZMYM2; ZNF593; WWTR1; MTF2; SIAH2; JARID2; NR3C2; SOX9; FUBP1; ZFHX4; HES1; DACH1; PRMT2; CAMTA1; PAX5; SFPQ; PEX2; TCF7; LMCD1; PRRX1; TOX; ETS2; NR1I2; NCOA4; ZBTB38; GATA6; BIRC2; BASP1; PTRF; TBX3; HOXC6; NPM1; TRIM29; ZNF264; MTA1; MYT1; SALL1; ZNF226; HMGN3; CALR; ELK3; MAGED1; ID1; HMGA1; CNOT2; SUB1; CREB1; NR2F1; MEOX2; NFKBIA; CEBPZ; IKZF1