Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID48167	Diltiazem	GSE92742	HA1E	Human	24h	10uM	EID0239

Response Information :

Types	Number	Response transcription factors
Up-regulation	382	TCFL5; E2F2; NR3C1; SSBP2; RELB; IKZF1; ZNF701; ZNF586; ZNF764; GATA3; PLAGL2; ZNF222; CEBPD; KDM5A; ZNF239; KLF13; TBP; BNC1; MEF2C; EGR2; NRBF2; ZNF227; OVOL1; CBFA2T3; ZNF180; WWP1; STAT2; ZNF124; NFAT5; HNF4G; TTF2; EVX1; ZNF225; CTNNB1; ZNF671; CCNT1; ONECUT2; TCF7; ZNF195; OSR2; TFCP2L1; TSG101; ONECUT1; ZNF226; NFX1; HOXC5; PIAS1; TOPORS; ASH1L; NFE2L3; PKNOX1; EHMT1; THAP10; DLX4; BAZ2A; HNF1A; MLLT1; CBX2; LIMD1; TGS1; ZBTB43; ALX4; MED14; ZNF629; POLR3C; SMARCA2; ZNF235; NEUROG1; HES1; EYA1; CIR1; DLX6; ADNP; ZNF623; RUNX1; HOXA3; HDAC4; PHOX2A; TERF1; E2F8; ZNF107; NCOA2; CHD2; MAML3; ZNF493; ZNF492; HNF1B; DOT1L; CHD4; ZNF587; ZNF223; SAP30; SAFB; ZNF682; ZBTB3; CREBZF; ZNF551; ZNF574; ZNF550; TFAP2B; PRDM1; SIX3; PRDM14; IRF2; MED12; ZNF408; PGR; FOXL2; DDX5; ZNF131; HEYL; ZHX3; AHR; CBL; ZNF214; ZNF22; ZNF343; RBL1; ZNF16; ZNF696; SPIB; LHX6; ING4; POU4F3; THRAP3; TBL1XR1; ARID4B; ZNF770; ZBTB44; MYT1L; TAF4B; CBX6; HIC2; E2F4; NR5A1; TFCP2; TAF1A; TCF20; ZNF212; ZNF516; HDAC11; IRF6; KAT7; SHOX; SP4; TUB; TRIM33; EMX2; ARID5A; ZNF3; CTR9; RFX7; ZFP36L2; KMT2D; ZNF219; PIAS3; TAF6L; ZNF10; ZNF721; KLF10; ZNF460; LPIN2; AGO2; NR5A2; CIITA; ZHX2; ZSCAN2; ZNF7; SPI1; ING1; NR1H2; ZNF254; TBR1; NR1H4; TSHZ2; ZNF8; MNDA; GFI1; DPF2; IRF5; IKZF3; FOXJ1; CAMTA2; SMARCA5; PAX5; ZNF507; CERS6; GATA4; ZNF695; ESRRG; MAPK8IP1; FHL5; HOXA1; THRB; ZNF440; KDM4A; IRX5; JUNB; MEOX2; NKX2-1; ZNF350; BRCA2; EGR4; MYB; ELF2; VDR; EYA3; RARG; BTG1; ZNF215; FOXJ2; SKIL; EZH1; HTATIP2; ZNF189; WDHD1; ERCC2; LEF1; KLF3; REPIN1; ZNF506; ZNF45; ZNF711; SSX3; ZKSCAN7; BRF2; ZNF34; CDIP1; UBTF; ZNF665; PML; HDAC7; BCLAF1; BRD2; ZNF329; MXD4; BCOR; NR3C2; BACH1; TRPS1; EP400; ZNF12; PBXIP1; ZEB2; ZNF257; ZFHX3; NCOA1; ELF4; BAZ1B; AFF1; SSX1; ZNF217; HOXC13; ARID3A; MTA2; KAT2B; PRDM5; ZNF135; HIVEP2; OLIG2; SNAI1; AFF2; TRIM25; NANOG; MDM4; ZXDC; EWSR1; GATA6; BARX2; CBX8; MBD4; RORC; ZNF611; TOX; HMG20A; ERBB4; RBBP5; TRIM32; HLX; TXNIP; TOB1; TLE4; YEATS4; SP1; NEUROD1; RXRA; BCL10; ERF; ACTL6B; NKX2-2; ZBTB25; PITX2; SND1; TFEB; SAP18; ANKRD1; ZNF141; HOXC10; SP2; KLF15; PRDM10; SKI; PCGF3; BCL3; NFATC3; LMCD1; ZNF304; ZBED4; BAZ1A; IFI16; ZNF264; PIAS2; FOXA2; ETV6; ZNF160; DNMT3B; ARNT2; TAF9B; NR1D2; RSF1; TSC22D2; ZNF710; ZBTB1; MED13; MYBL1; PREB; ZNF205; TULP4; BHLHE41; INSR; HLF; CSDC2; STAT6; FOXE1; ERG; PRKDC; ZBTB16; PQBP1; ZNF468; KLF6; ZNF165; CREB3L1; ELF5; TFEC; E2F3; NFE2; BBX; E2F5; ADRB2; ELF3; HDAC9; ETS2; RNF141; CRYM; MAGED1; TP63; ZNF423; TBX2; FOXG1; BCL11B; CUX2; PPARG; ID4; BCL11A; CALR; CTBP2; GATA2; SUV39H1; SOX17; KLF2; ESR1; SMARCA1; HOXD1; SMAD2; IRF9; TSC22D1; ZNF532; PIR; TBX3; PEG3; HOXC6; WT1
Down-regulation	379	HMG20B; PSMD9; LOXL2; NR2F6; PSIP1; NRIP1; RBM39; GTF2A2; PTTG1; GMNN; EDF1; TAF11; ITGB3BP; THAP11; DEK; FLNA; NELFB; UBP1; NPM1; CENPF; HMGA1; MMS19; ZNF692; ERCC3; TLE1; SMARCA4; TULP3; MYCBP; HMGXB4; PHF1; CCNH; CNBP; NR2C1; MTDH; WIZ; CCNC; BNC2; BRD7; ENY2; PDLIM1; MTA1; SUPT5H; GTF2IRD1; RFXANK; PAXBP1; HOXB2; RNF10; NONO; JUND; USP21; TAF6; MED21; AES; ZNF589; WWC1; GLI3; CNOT1; ZNF146; TADA3; HOXB6; COPS2; TRIP6; ZFP36L1; MED24; TEAD3; TAF10; GMEB2; NACA; PKNOX2; TRIP4; PFDN5; TCF25; PPRC1; RXRB; TP53; TRIM28; ELF1; SIM2; SIN3B; PTRF; CBX3; ZNF24; MEIS2; DEAF1; MNT; ZBTB17; ATF6; TGFB1; HOXB3; ZBTB11; NCOR1; SSRP1; EYA2; CRY1; PCGF2; ATF5; GTF3A; SMARCD2; SF1; SREBF2; C1QBP; ZZZ3; UBE2I; ZSCAN12; SIX1; ZNF76; GLI2; C1D; MED15; LZTR1; RBFOX2; MBD3; KDM2A; NKX3-2; HDAC3; LHX1; MAML1; CTBP1; CCDC59; NOC2L; EHMT2; KDM5B; HDAC6; TRIM27; CNOT6; CAPN15; HOXA10; PNRC1; VPS72; HOXB5; PSMC3IP; SNIP1; RFX5; ATF4; CITED1; HOXB7; HIF3A; MYF5; PCGF1; RNF138; ZNF248; IRF7; MYNN; TCEA2; ZBED1; SOX4; PBX3; ZNF232; ATF3; SOX2; ARNTL2; SREBF1; ZIC1; STAT5B; YBX1; ZNF500; CDK8; RAN; MYBBP1A; BRCA1; SUB1; SUPT4H1; HMGB1; REXO4; ATF1; SALL1; WWTR1; TRIM16; CARM1; HNRNPD; BTAF1; PSPC1; TFAP2A; VEZF1; JARID2; MLX; RBM14; ZEB1; CLOCK; CNOT2; FOXM1; ZNF133; SOX11; TOX4; NCOA6; EZH2; PBX1; FOXO4; SP110; MITF; NCOA3; APEX1; GON4L; CBFB; ILF2; ELK4; FUBP1; PLAGL1; PA2G4; ATF2; CHD3; MAZ; SLC2A4RG; MSX1; TEAD4; PHF20; ZNF32; HINFP; TRIM29; LDB1; ZNF302; MEOX1; EED; HOXB13; ZNF202; ZNF593; MXD3; ZNF83; ARL2BP; CEBPG; MED16; NFKB2; SALL2; MED7; XRCC6; KMT2B; HDGF; PBRM1; PRMT2; RHOA; SUPT7L; KAT2A; GABPB1; PMS1; SPEN; CBX4; ZNF528; SHOX2; FOXD1; SOX13; TCEA1; CDYL; HIVEP1; SMAD4; FOXF1; SMAD1; ENO1; MXI1; CIC; BANP; RCOR3; NEDD8; ZNF580; CHD9; BACH2; ABL1; TAF1C; YBX3; APBB1; PITX1; BRD3; ATN1; RLF; MGA; HDAC1; HLTF; UBE2L3; CERS4; TLE2; RELA; ETV1; SETD2; NR2F1; TRRAP; ZNF654; ZNF426; POLR2A; UIMC1; PRPF6; USP16; ZBTB18; PPARD; NFIB; ID2; FOXN3; CTCF; ISL1; SCMH1; NHLH2; ETS1; MEIS1; MBD2; BRD4; TAF4; TBL1X; HBP1; CRK; BTF3; YWHAB; SIX2; SMARCD1; CEBPA; TTF1; MAFF; TCEB2; NFKBIB; CHD1; MEF2A; MNAT1; RREB1; NR4A2; TGFB1I1; E2F6; MAF; STAT3; CIZ1; KLF7; DLX2; CREB5; NCOA4; CREB3L2; NR0B2; FOS; BHLHE40; BCL6; HOXA7; TWIST1; ZNF43; PAX6; TDP2; CREBL2; ZFPM2; EHF; ST18; CHD7; TAF9; PEX2; SMAD3; IRF3; SOX10; CENPB; ERBB2; ZNF266; ZFHX4; HMGA2; BLM; CUX1; JUP; EGR1; CITED2; ARID5B; HOXA5; KAT6B; STAT1; RUNX3; ZSCAN31; CD3D; DMTF1; KLF9; NFIL3; TRAK1; RBL2; ZNF512B; ZKSCAN1; CARHSP1; FOXO1; NR2F2; TAL1; RYBP; NCOR2; ID3; HEY1; CREM; LITAF; ZNF91; CREB1; SOX9; HHEX; BASP1