Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID47331	Pirfenidone	GSE70138	HA1E	Human	24h	0.37037uM	EID0224

Response Information :

Types	Number	Response transcription factors
Up-regulation	99	TCFL5; HLF; ATF5; CITED2; IRX5; RSF1; FUBP1; ERBB4; TFEC; MYB; HOXA1; POU5F1B; LIN28A; ZNF721; ETS2; WT1; MYRF; ZNF227; TFDP2; CXXC1; NFE2L3; LMCD1; THAP1; STAT5A; ZNF124; GRHL2; PREB; SND1; CARHSP1; CAMTA2; YAP1; SMARCE1; KDM5A; ZIC1; ZIC3; EGR2; PAWR; NANOG; RCOR3; HDAC4; TOX3; GATA6; KLF2; RXRA; PKNOX1; ZFP36L2; ZNF200; IKZF1; NAB1; NRBF2; TOPORS; DNMT3B; ZNF665; NR1H3; BATF; KLF9; MYCL; DBP; MLLT10; SMAD5; ZNF232; DNAJC1; HES1; ZNF7; PRRX1; ZNF264; HSF1; ZNF107; MED21; TCF7L2; HIPK3; E2F5; CRYM; ZNF430; MYCN; RBPMS; PLAGL1; NR4A1; ZNF652; EN1; TERF2; ID4; FOXL2; ZEB2; INSR; TSC22D1; EGR1; ID1; ZEB1; KLF4; ATF3; SAP30; NFE2; TWIST1; OSR2; TXNIP; GATA2; EGR3; MEIS1
Down-regulation	81	ZFHX4; ID2; EYA1; PTTG1; BTF3; HOXA11; ETS1; ZBTB40; LPIN2; FOXF1; MECP2; NFKB1; PKNOX2; TAF9; TBL1X; EYA2; YWHAB; HEY1; ZFP36L1; MDM2; ETV5; TLE1; CBFA2T2; SIX1; BACH2; MBD2; RYBP; ISL1; LITAF; IRF9; PITX1; MED13; KDM5D; RFXANK; FOXF2; IRF7; CENPF; NPAS2; ZFHX3; RXRG; SMAD7; SP100; FOXD1; HOXB13; SUB1; SIX2; TCF21; ZNF467; BHLHE41; RNF10; WWC1; EDF1; NKX3-1; MSX1; GTF2IRD1; ZNF331; HMGB2; PAX5; PRKDC; SERTAD2; TGFB1I1; SMAD1; LOXL2; SATB2; SOX9; GTF3A; SHOX2; POU2AF1; SATB1; HHEX; HMGB1; ASCL1; ZNF91; DACH1; MAF; MAGED1; PBX3; NR4A2; PPARG; ARNT2; ZNF586