Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID47265	Talazoparib	GSE70138	HA1E	Human	24h	0.123457uM	EID0224

Response Information :

Types	Number	Response transcription factors
Up-regulation	92	NFKBIB; MEF2C; THRAP3; MDM4; RBBP5; STAT2; CBX6; TGS1; NFYC; LPIN2; SNW1; SAFB2; HLF; ARNTL; COPS5; UTF1; SAFB; SUV39H1; ESR1; YEATS4; PIAS1; MAFG; SKIL; ELK3; MEOX2; NANOG; KLF13; ZNF589; ARID5A; IKZF1; ZNF721; TCF12; ZNF160; POU5F1B; ZNF764; CNOT3; ZNF551; ZNF671; ZNF444; RNF111; TERF1; AFF1; IL16; ZNF586; TRIM32; ZNF587; PIR; JUP; TRIM22; DPF2; MDM2; SMAD2; ZNF652; IFI16; WWP1; CEBPZ; ZNF217; TCF7; SAP18; LOXL2; MSC; BRD4; LIN28A; MECOM; FOXO1; NFIC; ZNF146; RBBP8; TAF1D; ZNF264; ZNF134; TRIM29; TOX; SOX17; AES; ZNF329; NCOR2; MNDA; DNMT3B; ZNF91; NCOA2; ETS2; ZNF281; RUNX1; EGR1; THAP11; TWIST1; PPARG; MAFB; TLE4; POU2AF1; PEG3
Down-regulation	96	RHOA; KLF11; IRF1; CEBPD; CREB1; CNOT6; MEIS2; BASP1; CDK8; ILF2; PHIP; WNT4; RFXANK; HOXA10; HOXD11; CREB3; HOXB13; RAN; TLE1; PSMC3IP; EYA1; ZNF133; PFDN5; TFDP2; ID3; BTG1; SOHLH2; CITED2; NRIP1; NR4A2; RUVBL2; PSIP1; ZNF83; NPM1; NR0B1; ISL1; YBX1; NKX2-1; GATAD2A; PTTG1; CTBP1; HOXB7; NR1H3; IRX5; ZNF516; HMGB1; RAD21; PSMC3; CREB3L2; KLF7; JUNB; INSM1; ZNF331; UBE2B; NKX3-1; SOX11; ZNF432; ZBTB20; EDF1; SERTAD2; ZNF302; SHOX2; KLF1; SIX2; WT1; BACH2; CTBP2; HLTF; HMGB2; SMARCA1; MYCN; PBX3; WWTR1; ATF3; FOXC1; TAF7; UBE2I; ENO1; MYBL1; HTATIP2; EHF; PBX1; KLF10; NFIB; OSR2; TSC22D1; PAX6; GATA2; ZBTB38; KLF4; ID1; DACH1; LEF1; MEIS1; SSBP2; TBX2