Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID47072	Talazoparib	GSE70138	HA1E	Human	24h	0.37037uM	EID0223

Response Information :

Types	Number	Response transcription factors
Up-regulation	113	E2F2; VGLL4; TLX3; SOX5; ZSCAN9; GATA1; TULP2; LYL1; BNC1; ZNF778; THAP4; ERF; OVOL1; BAZ2B; E2F3; KLF10; ZNF10; ZNF667; CARF; ZNF222; ATOH1; SKIL; ZNF93; EGR4; NCOA4; SMAD2; KLF1; MYT1; ZNF223; ZNF614; POLR3C; PROX1; MED20; ZNF432; DDX17; HOXD3; NCOA1; PFDN5; TAL1; CCNE1; ZNF91; CHD3; ING2; TAF12; ZNF665; TSC22D1; HSBP1; NFE2; ZNF350; TCEB2; ZNF124; ZBTB20; PITX2; TFDP2; BCL11B; ZNF175; ZNF571; ASCL1; ZBTB43; PKNOX1; TXNIP; HOXD10; OLIG2; NRBF2; HOXD11; HOXB13; ZNF165; BATF; ZNF586; BCL6; IRF6; SAP30; TFCP2L1; MAX; STAT4; CTNNB1; ZNF329; SMARCA2; NLK; VGLL1; CUX2; ZNF189; BRD2; ZNF211; GATA2; ZSCAN18; TLE2; NPAS2; ETS2; CREM; SMARCA1; NR0B1; NFAT5; ZFP36L2; NKX2-2; ZNF721; ZNF544; ZNF12; ZNF22; BBX; MAFB; DDIT3; ING3; ZNF148; KDM5A; DACH1; ZNF83; GATA6; ZBTB38; EGR2; TOB1; NFIB; ESR1
Down-regulation	66	MYCBP; MED4; PIR; ETV5; KDM4C; ARNTL; CENPB; NR2F1; RBBP8; INSR; RBPMS; SLC2A4RG; ACTL6A; MED24; ZNF107; PRKDC; ARID1A; CBX6; MAZ; FLNA; GTF3A; SNAI2; SHOX2; NFYC; ATF7IP; YWHAB; HNRNPD; C1QBP; ZMYND8; CERS6; BATF3; CTR9; YEATS4; HOXC10; ZNF652; ZNF512B; BCL3; YBX3; HMGA1; ERBB2; CITED2; TGFB1I1; CHD7; ARNTL2; MTA1; HOXB2; ZBTB18; HHEX; SIX1; MSX1; IRF7; ELF3; MED21; MEIS2; ZFP36L1; HOXB7; TOX3; SOX9; THAP11; LEF1; KDM5D; TRIP6; PPARG; EGR1; SSBP2; IKZF1