Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID46851	Digoxin	GSE70138	HA1E	Human	24h	0.123457uM	EID0222

Response Information :

Types	Number	Response transcription factors
Up-regulation	108	SPDEF; CCNH; SMAD3; UBE2L3; POLR3F; CSDE1; HMGA1; FOSL1; ESRRG; THAP1; PIAS1; ZNF589; DEK; SIX3; PMF1; ANKRD1; HMGB2; SF1; KAT6B; MLX; CUX2; C1QBP; RBPJ; ACTL6A; DAXX; HHEX; FUBP1; MAK; ZNF215; ZNF770; MYB; SERTAD2; SMARCA1; KLF1; NFE2; HDGF; CDC5L; PLAG1; NAB1; RNF138; BRD4; HOXB6; MAFG; TAF9; RBM39; PCGF1; RFXANK; HOXB5; RYBP; TCF7L2; PAX5; HES1; SREBF1; TGIF2; HLX; HDAC4; POU4F1; ARNT2; ZNF711; EDF1; ZNF281; NFYB; SAP18; SMARCB1; CRY1; POU4F2; NR0B2; DLX2; BCL6; JARID2; NR4A3; CERS6; CBFB; SSBP3; CREB5; TBX3; HOXB7; AES; SOX9; ZBTB18; SMAD1; CREM; APEX1; TXNIP; PAX6; PSMD9; INSR; SSX1; GATA2; IKZF1; SNAI2; YEATS4; MECOM; ERBB4; MNDA; KLF10; ZEB1; CREB3L1; MITF; MSX1; OSR2; CEBPA; JUND; CEBPD; MTA1; KLF5; PPARG; PUF60
Down-regulation	100	NRIP1; PNRC1; BHLHE40; FOXO4; MAGED1; CARHSP1; ZNF419; ADNP; TRRAP; HOXA1; RNF4; SIAH2; SMARCD3; SAP130; RCOR3; HMGB3; FLNA; TSC22D1; TRIM24; MED21; MECP2; HOXA10; HMGN3; ZNF532; ARNTL2; ERBB2; ZNF264; HIPK3; MEIS1; CBX3; NR4A1; CBX5; ZNF426; ADNP2; ZNF606; TLE4; IRF4; CDK9; RXRA; ZBED2; IRF5; ZNF551; HOXA5; POLR2A; CREB3L2; RLF; MEOX1; ZNF200; ZBTB24; ELF5; TLE1; VGLL1; SMAD7; ZNF410; CTNNB1; TRIB3; MAF; THAP11; ZNF430; ZNF671; ZKSCAN1; SPEN; GTF3A; SSBP2; MEF2A; RORA; EYA2; ZNF91; MED15; PAX8; EPAS1; ZNF148; ZNF134; LEF1; ZNF652; TCFL5; ZNF665; ZNF587; ID4; ZNF304; ZSCAN18; ZSCAN31; ZBTB16; TGFB1; FOSB; SPIB; MKL2; NR0B1; EHF; CITED2; ZEB2; HOXC10; WT1; TCF4; MAFB; PEG3; ZNF586; E2F2; NR3C1; MEF2C