Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID46775	Canagliflozin	GSE70138	HA1E	Human	24h	0.123457uM	EID0221

Response Information :

Types	Number	Response transcription factors
Up-regulation	84	MYB; ZBED1; EHF; INSR; CRYM; MNDA; CBFA2T3; HTATIP2; TERF2; ATN1; ETS2; IKZF1; COPS2; CHD7; SHOX2; BCL11A; REPIN1; TCF7L2; AES; SUV39H1; EGR1; CTBP1; SOX11; ELF1; ACTL6B; ZBTB16; SUPT4H1; PLAGL1; ERG; HES1; CDK8; CREG1; MEOX1; ZNF264; ZIC1; BRD4; ZEB1; CSDE1; RUNX1; ZKSCAN1; ZNF536; WNT4; DAXX; PPP1R13L; NFE2L3; RBPMS; INSM1; NPAS2; PIAS1; YBX3; FOXO1; E2F8; JUNB; MYRF; ESRRG; TRIM16; LITAF; CEBPD; PAX5; HOXB5; KLF9; HOXB2; APEX1; SNAI2; DACH1; ARNT2; FOXN3; SSBP2; LMCD1; AEBP1; CEBPB; CALR; GATA2; NR2F1; ZFPM2; MEIS1; THAP11; PAX6; EGR2; LEF1; IKBKAP; KDM5D; SOX9; CREB1
Down-regulation	52	TOPORS; PSIP1; PHF1; ARRB1; TBL1X; CTNNB1; ZFX; CEBPG; SAP30; DMTF1; ZNF124; ZNF189; BCL10; HEY2; AHR; SMAD2; BRF2; ASH2L; EYA2; FOXD1; HIPK3; TOX; BBX; ID2; ZNF331; FOS; MAF; ZNF266; SMAD7; ZNF721; PEG3; FOXG1; HOXC10; MYBL1; HMG20B; RBBP8; TRIM22; SREBF1; NANOG; MSX1; ZBTB20; ZSCAN18; HMGB3; ESR1; NR1D2; WT1; WWTR1; MKL2; ID4; TXNIP; E2F2; ZNF586