Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID46671	Digoxin	GSE70138	HA1E	Human	24h	0.37037uM	EID0221

Response Information :

Types	Number	Response transcription factors
Up-regulation	136	BATF; MAFF; KLF9; BATF3; SSX1; TFAM; CDK2; KDM5A; MYRF; ZNF226; BMI1; SP110; RUNX3; HSF2; SFMBT1; BCL10; FOXD1; PSMD9; IRF9; CCNH; FOSL1; ZNF143; ZBTB17; BRPF1; PRDM13; ATF3; CHD8; ATN1; SOHLH2; SOX9; NR3C1; STAT5A; IRF6; SUPT4H1; SUB1; PREB; NAB1; SHOX2; PPRC1; GATA6; CITED1; UBP1; TWIST1; INSR; SOX10; NFYC; RARA; ZNF324; ZNF24; CHD1; CDC5L; BCL11B; PIAS1; SMAD5; AFF4; ZMYND11; ZNF227; PSMC3IP; HHEX; ZNF654; OLIG2; ARID5B; HOXB7; FOSB; SP100; LHX2; ZNF711; DNAJC1; SPEN; IRF1; IRF7; IRF8; MLX; BTAF1; VDR; IRF4; CREB5; CREBZF; NR5A2; BRD4; FOXF1; STAT1; DLX2; ELF4; TDP2; FOXG1; BHLHE41; ARID4B; TRIM29; MED21; IFI16; CREBL2; CREM; ZBTB20; NKX3-1; GATAD2A; ELF1; INSM1; CD3D; ENY2; MED14; ZNF266; MED1; CRY1; EGR2; PPARG; NEDD8; SSBP2; C1QBP; HES1; FUBP1; CUX2; MYB; ENO1; PURA; FOXJ3; ETS2; RSF1; ETV5; HEY1; ZBTB16; PAX5; MITF; ZNF589; MYBL1; DACH1; PAX6; NFE2L3; TFAP2C; HDAC9; TOX; ID4; KLF6; NANOG; LEF1; EGR3
Down-regulation	144	XBP1; NR2C1; ZNF133; RNF10; PAX8; PRRX1; HOXA3; SOX12; PITX1; MLXIPL; ID1; ZNF337; PEG3; HCFC1; TCF4; REPIN1; RBFOX2; SMAD6; EHMT2; ERBB2; ZNF423; HDAC7; HOXA4; MDFI; ZNF85; ZNF205; ZFHX4; STAT6; MAGED1; TCF15; AFF1; TCEA2; RREB1; SMARCD3; TSC22D1; NONO; PHOX2B; BHLHE40; ZNF430; ZBED2; HMX1; EYA2; ZNF84; GTF2IRD1; CRYM; MED25; ZNF189; ZNF415; RNF141; ZNF32; CCNE1; ZNF117; HNF4A; CIC; MYF6; FOXO4; MEIS1; ZFHX3; HMGB3; ZNF556; HOXA5; TBL1XR1; SIRT2; TBL1X; ZNF250; ZNF606; EVX1; TAF4; ZNF75D; PRKDC; PRPF6; SIX2; PHOX2A; TRIM28; TCEB2; ZFP64; ZNF544; HOXA10; CREB3L1; DLX5; SIX1; PNRC1; PITX2; NHLH2; ZNF135; ATF4; ELF3; ACTL6B; MAZ; NCOA4; TCF7L1; ID3; TRIM32; SLC2A4RG; EMX2; ZNF43; HLX; ZNF93; NR1H4; ZNF248; GTF3A; ZNF532; SOX17; URI1; LYL1; ZSCAN31; SMAD7; FOXO1; UBE2B; YBX3; ZNF665; MLXIP; CARHSP1; KLF2; APEX1; HBP1; SREBF1; TAF10; POU2AF1; LPIN2; ISL1; FOXL2; NEUROD1; TAL1; TLE4; MYT1L; TRIM24; TGFB1; JUNB; NRIP1; GATA2; ZNF91; ZSCAN18; LOXL2; SMAD1; NFIB; ESR1; TBX3; JUP; MAFB; EGR1; TCFL5; KDM5D; E2F2