Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID46595	Canagliflozin	GSE70138	HA1E	Human	24h	0.0411523uM	EID0220

Response Information :

Types	Number	Response transcription factors
Up-regulation	174	SOX5; DLX5; GLI3; JUN; HLTF; LDB1; NAB2; MTF1; MEF2C; CCNH; RFX5; CBX5; EYA2; MXI1; BNC2; KDM5A; CALCOCO1; SOX2; CLOCK; PBX2; DDX17; LPIN2; PURA; RORC; SSBP3; TRRAP; PHF1; HMGA2; NFKB2; GLI2; CCNE1; NR0B2; SALL2; NFKBIB; MXD3; RNF111; BBX; MDM2; SMARCC2; BRF2; PA2G4; HOXB1; ITGB3BP; ZBTB18; MTDH; TRIM22; SMARCA5; SIN3B; TSG101; ALX3; ZNF148; RARB; SMARCA1; TBPL1; STAT4; TLE4; BRCA1; HOXB2; GON4L; BARX1; CRYM; CTBP2; ZBTB17; CREB3L2; ZNF345; NFAT5; HSF4; NRL; IKBKAP; SIX2; IRF2; ST18; MED13; FOXK2; GATA1; WHSC1L1; ZNF589; RARG; MAML1; ZNF771; MYBL1; MNT; XBP1; IFNB1; ZFHX3; SP140; SP3; NR1H3; RSF1; KLF15; PFDN5; HOXC10; PRMT2; MYRF; NHLH1; TCF7L1; MKL2; SMARCD3; COPS5; ZFP36L1; ADNP; EZH1; TAF12; KLF1; NKX2-1; RBL2; STAT6; SHOX; PTTG1; TAF1D; SMAD7; RAX; BACH2; FOXO1; HOXC6; TEAD3; NCOA3; ZNF281; ASH2L; ZBTB44; RORA; JUND; KLF2; TULP3; CD3D; TAL1; SND1; ZNF467; MED7; CITED1; POU2AF1; GTF3A; DDX5; ASCL1; NFIC; SOHLH2; ZIC1; ING2; STAT2; NCOA2; CHD4; SOX10; THAP11; ZMYND8; VGLL1; SAP30; ATF3; RARA; TRPS1; PAX5; GFI1; RBFOX2; HMBOX1; ZBTB38; HOXC4; TBL1X; ZFHX4; PITX1; MEOX1; TGIF1; HMG20B; BCL11A; EHF; MAF; KLF9; LITAF; ARNT2; PEG3; ZNF91; E2F2; PSIP1; TOX3; TRIP6; ESR1
Down-regulation	182	HOXA10; HOXA5; MNAT1; BIRC2; ARID5B; MED6; ZFX; DACH1; CEBPZ; SFPQ; TEAD4; NFKB1; NFIB; MNDA; ERG; SPEN; SCAND1; ETS2; TLE1; THAP10; VEZF1; STAT1; ZEB1; PHIP; SRF; SUB1; MTA1; ERBB2; RLF; BCLAF1; ZNF131; MYCL; ZNF140; SNW1; FOXJ3; HOXA7; PUF60; ORC2; POU3F2; ZNF177; VGLL4; ID3; LMCD1; FOXC1; TAF9B; PRDM4; BASP1; ZNF227; YBX3; NR2F6; SATB2; PQBP1; PAWR; KLF5; ZBED1; MEIS1; BCL3; HOXA4; TCF7; MEOX2; IRF9; DMTF1; HBP1; TRIB3; BHLHE41; CHD7; CDYL; ZNF292; ANKRD1; ARNTL; MECOM; TRAK1; FHL2; HSF2; JUNB; IRF1; SMAD3; RCOR1; NFYB; TDRD3; CREB1; HHEX; TRIM16; KMT5A; PPARG; RBM39; ZNF195; TMF1; BATF3; AFF1; KMT2A; CRY1; CHD1; UBE3A; PROX1; PRDM10; RXRA; WWTR1; SF1; TEAD1; ZNF266; E2F6; WWC1; PAX6; OSR2; CTNNB1; HOXA11; ZBTB11; RNF4; HIPK1; ZNF7; ZNF180; INSR; NKX2-2; ATF4; MLLT10; ZFPM2; RBPMS; PAXBP1; FLNA; RUNX1; DNAJC1; MEIS2; FOXA2; NKX3-1; IRF7; NPAS2; ZNF468; OLIG2; TP63; PPP1R13L; FOXN3; C1QBP; KLF6; AHR; HIRA; ZNF189; ING3; TGFB1I1; NR2F1; BMI1; SSBP2; CTBP1; LOXL2; E2F5; AGO2; APEX1; ARNTL2; TCF7L2; CREM; HLX; TRIM29; DNMT3B; NFE2L3; HEY1; ZNF580; ZNF721; REL; MYB; JUP; GATA2; MSX1; RBBP7; RAN; PLAGL2; MED14; TFAP2C; MED21; ZNF226; ZNF516; SERTAD2; ZFP36L2; TOX; GATA6; TBX2; TBX3; RELB; SSX1; NR3C1; CEBPA; EGR2; IKZF1