Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID46593	Canagliflozin	GSE70138	HA1E	Human	24h	0.37037uM	EID0220

Response Information :

Types	Number	Response transcription factors
Up-regulation	131	HLTF; ZNF512B; NCOA2; TWIST1; CERS6; SUB1; SMAD3; ZEB1; SOX9; SREBF1; LDB1; SAP30; SUPT7L; ZNF281; MED24; LEF1; ZFHX4; BRD3; WT1; SNAI2; BNC2; ZNF302; MAML1; ITGB3BP; GLI3; SMARCA1; KAT2B; TLE4; PEG3; MAFB; IFI16; SMARCA2; KDM4C; HMG20A; RNF111; EYA2; TRIM22; SATB1; SCMH1; RARA; IRF9; PLAGL2; VGLL4; PBX1; VDR; NR2E1; TRIP4; ZFPM2; CBFB; ERG; PRKDC; PLAG1; POU2AF1; NFIC; CEBPA; TAF1D; BACH2; TSC22D4; POU4F1; ING2; PCGF2; HOXC6; STAT5A; RORA; NFYC; ZNF423; AEBP1; LZTS1; RXRA; NAB1; PLAGL1; JARID2; NRIP1; DLX2; BNC1; ZBED4; URI1; KLF9; BATF; TFAP2C; LMCD1; SP3; ZNF267; FOXA1; IRF7; HOXD3; PBX3; CEBPD; NFATC1; FOXN3; ETV5; IKZF1; KLF10; CEBPG; TULP4; BRD4; SMAD1; ZNF91; CREB3L1; BCL10; HIC2; SHOX2; DDX5; WWP1; CD3D; SMAD2; HOXC10; LOXL2; TLE1; PHOX2B; SOX17; PAX5; THAP11; BCL11B; HOXB7; KLF7; MEIS2; STAT1; PITX1; TOX3; ZNF226; TOX; ZNF217; BCL3; ZBED2; PSIP1; GATA2; HES1; ABL1; PUF60; ESR1
Down-regulation	144	CDK7; MXI1; SMAD4; RNF14; KDM5A; KAT6B; HOXD10; ORC2; ZBED1; HMGB1; NR2C1; FHL5; ID1; MITF; POU2F1; ST18; ARID1A; ZNF248; UBE2B; GABPA; ZSCAN5A; ING3; HOXA10; KLF6; ZBTB17; RBBP7; CITED2; ZNF33B; SALL1; INSM1; CNOT3; PPARGC1A; PPARG; DNAJC1; MYF6; ZNF136; CHD8; ILF2; ARNTL2; AFF4; NR4A3; ESRRG; CBX6; STAT6; RAD21; NFYA; MED6; FOXJ2; PNRC1; REPIN1; IKZF5; TDRD3; PHIP; FLNA; RYBP; NR0B1; TDP2; DLX4; NKX2-1; TRIM28; ZNF23; SOX15; TGFB1; PATZ1; ZNF557; ID3; ZNF536; TAF5L; CREB3L2; ENO1; CUX2; ZNF430; ZNF124; HBP1; NPM1; MLLT10; HEY1; ELF5; MXD4; HOXD11; SOX10; NKX2-2; KDM5D; TAF1A; KMT2A; NFE2; CREM; AES; RCOR1; ZNF83; TAF7; HMG20B; TFEC; C1QBP; ZBTB20; ZNF189; GTF2I; CREB1; TGIF1; ZMYND8; SPIB; ZNF44; ZBTB18; ZNF611; HMGN3; MEOX1; CREG1; EHF; HOXA11; ZNF544; TSC22D1; UBE2I; EPAS1; ZNF711; IRF4; SLC2A4RG; ZNF652; FOXC1; MED1; ZNF589; TBX2; INSR; TFDP2; PGR; CARHSP1; LITAF; CALR; BCL11A; TBL1X; TOB1; KLF5; NR3C1; ZBTB38; NR2F2; DACH1; TXNIP; ATF3; EGR2; GATA3; TRIP6; EMX2; RELB; NFATC3; TCFL5