Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID46591	Canagliflozin	GSE70138	HA1E	Human	24h	3.33333uM	EID0220

Response Information :

Types	Number	Response transcription factors
Up-regulation	126	DPF2; RNF111; MED16; POLR2A; ARNTL; ASCL1; HSBP1; SALL1; NAB2; PSMC3; MEN1; DDX54; LYL1; RUVBL2; HMG20A; CBFA2T3; CEBPA; CUX2; HDAC5; ARID4A; ZNF512B; THRA; PIAS1; ZNF282; DLX5; RCOR1; ERG; HTATIP2; NOC2L; BRF2; HBP1; TCFL5; SND1; POU5F1B; IRX4; NR0B2; NR1I3; SMAD3; NFE2L1; PKNOX2; TSC22D4; ZNF688; HIPK2; ZNF267; TERF2; LPIN2; OLIG2; HHEX; DNAJC2; ETS2; UIMC1; ZNF446; MED24; SF1; NFX1; PPARD; HDAC11; CITED1; TFCP2; CUX1; COPS5; ZNF215; HIPK1; OVOL1; EYA1; MNDA; ID4; ZNF189; HEYL; RNF141; ZNF721; EZH1; NR0B1; TRIM16; SOX3; ZNF611; AGO2; ARID1A; MAFB; FLI1; GATAD2A; ADRB2; WDHD1; ZNF516; NFIB; HAND1; NRIP1; ZNF160; CERS4; ZBTB16; MKL2; TRIM22; RREB1; DLX2; SERTAD2; HLX; ASH2L; TBL1XR1; GFI1; MYB; ZFP36L2; NKX2-1; FOXO1; IFI16; ZBTB18; BCL11A; NPAS2; NR3C1; GATA4; KLF9; HEY2; ZHX2; TFEC; TFAP2C; CALR; SOX17; MYBL1; NANOG; ZNF423; PIR; MAF; ZNF652; ARNT2; HES1; LOXL2; TXNIP
Down-regulation	146	CCNE1; ZNF91; CERS6; SUMO1; BBX; SP100; KLF4; ZNF562; ZNF177; LDB1; PAX6; MECOM; ZNF266; KDM5D; TFAM; ZBED1; FOSB; CBFA2T2; MITF; ZNF148; ZNF432; ZMYND8; PITX1; HOXB13; HOXB6; OVOL2; YBX1; ZNF133; HDAC1; MECP2; DEK; PBX2; MYCL; HOXB7; CREB1; ZNF419; ERCC3; NR4A3; NFE2L3; TOX3; KLF11; ST18; ZNF211; PBRM1; VEZF1; RYBP; CSDE1; EMX2; GRHL2; PCGF2; SMARCB1; TOX; ZNF354A; HNRNPD; NR4A2; GATA2; SAP18; ZNF331; CCDC59; BCL6; PSIP1; NFAT5; SETD2; HOXB2; TBL1X; ZNF248; CARHSP1; CEBPG; ZNF345; FOXN3; SIAH2; ZNF136; ZNF43; JARID2; BTF3; ZFP69B; ZNF14; CBX7; CRY1; TEAD1; SP110; SMARCA1; TGIF2; CD3D; TAF11; NKX3-1; MEOX1; URI1; ZNF304; EYA2; ING2; YAP1; MED1; SKI; ELF5; RERE; MEIS2; NHLH2; TOPORS; BATF; ZNF529; SPIB; BRD4; YWHAB; REST; SSRP1; ZNF83; HOXB5; DACH1; IKZF1; CREB3L1; NR3C2; SSBP2; TGFB1I1; EHF; ATF4; ING3; CTBP2; GATA3; EDF1; ZEB2; ISL1; HDAC9; MLXIP; ZNF468; HMG20B; ERBB4; IRF7; AHR; ZBTB38; SOX9; SNAI2; RELB; OSR2; RBPMS; TBX2; NFATC3; ZFP36L1; FLNA; ZBED2; E2F2; ATF3; EGR1; ZNF586; SUV39H1; GATA6