Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID46564	Istaroxime	GSE70138	HA1E	Human	24h	0.123457uM	EID0220

Response Information :

Types	Number	Response transcription factors
Up-regulation	74	MYBL2; SREBF2; SREBF1; DPF2; MED16; ERG; MAZ; TGFB1I1; MNT; CEBPA; MYCN; EGR1; BNC2; POLR2A; NKX3-2; TULP3; NEDD8; C1D; TRIP4; ERBB2; ATF3; HLTF; RBPMS; ZNF286A; TADA3; ZFHX4; TRIM29; JUND; TSC22D2; NOC2L; POU5F1B; TRIP6; ZNF267; FOXM1; EGR3; MED20; TAF1D; NAB1; ZNF146; PRMT2; BATF3; MYB; ZNF552; IRX4; ZNF512B; NRIP1; STAT3; CREBL2; PAX6; PBX1; REST; RXRA; ENO1; CRYM; YBX3; CALR; PEG3; RUNX1; ZIC1; SHOX2; MAFB; TFAP2C; HMG20B; GATA3; KLF10; SSBP2; CREB1; LOXL2; THAP11; ZFP36L1; PUF60; GATA2; EGR2; ESR1
Down-regulation	115	ZNF248; CCNE1; MYBL1; ZNF532; TAF7; SATB2; ZBTB20; SMAD7; TAF1A; MBD2; NR3C2; ASXL1; RBL2; CBFA2T2; ZNF133; MECOM; ZNF354A; HOXB9; HMGB1; SNAI1; ZNF148; MED17; FOXC1; ZNF415; TEAD1; ZNF573; AATF; NR4A2; E2F5; PHF1; NPM1; MYRF; EHF; TOB1; SIX2; RCOR3; MXI1; BRD2; TCF21; BBX; ING2; ZBTB11; IRF2; RNF6; ZNF10; KAT2B; JAK2; BCL10; YAP1; FOXA2; STAT6; HOXD3; STAT4; RBBP7; BACH2; TBX3; TULP1; CHD7; CENPF; TERF1; SP140L; PKNOX2; VDR; KLF5; ZNF200; SNAI2; HES1; UBE2I; ZEB2; ZHX2; SERTAD2; MED14; KLF2; SOHLH2; ZFP36L2; WNT4; YWHAB; EN1; SMARCA1; HMGB2; HOXA11; NFE2L3; RREB1; ZNF222; LPIN2; CITED2; MLXIP; GATA6; SMARCA2; HIRA; CREM; EYA1; ZNF432; NLK; TXNIP; SSX1; IKZF1; NKX2-1; AFF1; KDM5D; RELB; ZBED2; PITX2; ELF5; NR3C1; SUV39H1; LMCD1; MAF; MAGED1; CREB3L2; E2F2; TCFL5; ID1; ZNF586; NFATC3