Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID46563	Istaroxime	GSE70138	HA1E	Human	24h	0.37037uM	EID0220

Response Information :

Types	Number	Response transcription factors
Up-regulation	87	MNDA; FOSB; CHD1; HEY1; SAP30; ARID4B; ARNTL; ATF7IP; SOX9; BTG1; CREBL2; FHL2; RFX5; RFC1; PNRC1; TFCP2; MSX1; RFXANK; ENO1; DAXX; DLX2; WWTR1; TAF9; NR2C1; TGIF1; DDX5; YAP1; GTF2I; PIR; BRD3; UBE2I; RBBP8; JAK2; BHLHE41; RBM39; CHD9; APEX1; TRIM32; NR1H2; NCOA1; TAF9B; PEX14; EDF1; MAFB; CTBP2; NRIP1; PBX3; SFPQ; HNRNPD; KDM5A; AFF1; KLF4; TRIM29; TRIM22; FOXJ3; YBX3; DMTF1; MEOX1; BMI1; CEBPB; CTBP1; AHR; TP63; BRD2; MED21; CRK; TFAP2C; MED1; REPIN1; IRX5; TBX3; PCGF2; ATF6; MLLT10; THAP11; IKZF1; PPARG; PAWR; HMG20B; NKX3-1; LOXL2; ASCL1; MEIS2; PUF60; HOXC6; EGR3; PSIP1
Down-regulation	175	CTNNB1; ZNF117; SNAI1; ZNF606; TAF4; SSBP2; MYBL1; ZNF44; SMAD7; PRRX1; ZNF85; HDAC5; NFE2; ZNF768; PLAGL1; ZNF512B; ESRRG; PHF20; ACTL6B; ZNF43; MYT1; NEUROD1; ELF4; GATA1; ZFPM2; TRIM24; SRCAP; PITX1; ZNF410; ID1; OVOL2; ZSCAN18; TGFB1; ZNF665; ZNF573; PEG3; ZNF136; ZNF354A; ZNF667; MLXIP; ZNF571; NAB2; ZNF135; SOX11; ZNF701; STAT2; TLE4; CIC; ERF; ZNF544; LYL1; TWIST1; ZNF415; KMT2B; PAX1; POU2F1; NR1H4; L3MBTL1; ZNF239; PFDN5; NFATC1; NKX2-5; TLE1; ZFP36L2; NKX2-2; MYT1L; ZNF91; HES1; EP300; TAF1A; CSDC2; EP400; TCF4; ZNF264; HSF1; ZNF669; MYCN; NR5A1; ZNF223; ZNF222; OVOL1; RORA; ZNF281; MAFG; ZNF419; OLIG2; ZNF529; ZNF440; ZNF467; ZNF23; FOXN3; LZTS1; RNF6; ZNF350; CALR; ZNF721; KAT2B; RNF10; CENPF; ZNF93; CCNE1; ZNF587; PRDM2; PLAGL2; DLX5; MED12; TAL1; HMGB1; PBX1; SOX12; KLF10; ARNT2; ZNF671; TRPS1; MECOM; ZNF180; JUNB; ZNF22; FOXO1; STAT4; EGR4; HMGB2; HHEX; KLF1; ELF3; VGLL1; INSM1; RBPJ; FLNA; FOXJ1; ZNF304; BACH2; HIPK2; GATA3; DDIT3; POU2AF1; E2F5; HLX; HOXD3; FOXF2; NR0B1; ZNF652; ZNF493; NFIC; TRIB3; ESR1; SNAI2; ZNF165; CUX2; SPIB; FOXG1; HLF; NR3C1; VDR; EMX2; RELB; ID3; MKL2; KDM5D; ZNF160; TBX2; ZEB1; BCL11A; LITAF; CREB3L2; MYB; ADRB2; SSX1; NFATC3; TXNIP; NR2F1; E2F2; EGR1; SUV39H1; TCFL5