Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID46554	Ranolazine	GSE70138	HA1E	Human	24h	10uM	EID0220

Response Information :

Types	Number	Response transcription factors
Up-regulation	79	IRF7; RUNX3; CAPN15; CNOT2; CEBPA; CD3D; BNC2; ZMIZ2; UBE2I; ZNF148; ZNF91; ZNF200; TAF4; MED7; NFE2L3; ZMYND8; CBX7; TAF11; SLC2A4RG; RARA; KDM5A; DEAF1; CHD9; RREB1; MNAT1; RXRA; ZNF587; MECOM; CTBP2; ID4; PURA; ZNF468; MED1; PLAGL1; WT1; ZEB2; UBE3A; MXI1; ZNF652; HMGN3; IRF8; SP140L; CTBP1; ZNF44; MEIS2; SMAD6; TOB1; SMARCD3; HOXB7; RUNX1; IL16; MAGED1; JARID2; TRIP6; FOXO1; CEBPG; JUP; MLXIP; CARHSP1; SIX1; ZFPM2; ZIC1; SERTAD2; AEBP1; NR2F1; GATA6; IRF4; IKZF1; DACH1; HMGB3; PUF60; FLNA; ELF3; KDM5D; GATA2; LOXL2; HES1; EGR2; PPARG
Down-regulation	148	DLX5; BAZ2B; DLX2; SREBF2; INSM1; NFKB1; MSX1; FOXF2; TAF4B; ZNF536; ZNF223; NEUROD6; PFDN5; ORC2; SIM1; SMAD9; NR2E1; CUX2; MYCN; ZNF667; ZIC3; ZNF219; AFF4; TBR1; ZNF253; ZNF135; SOX3; ASH1L; TBL1XR1; HOXC11; MTDH; ZNF286A; SOHLH2; TCF7L1; NEUROD1; LHX2; HMGA1; E2F1; MED31; FEV; CNBP; FOSB; ZNF415; BNC1; KLF4; ELF4; PAX6; HIPK3; FOS; SSBP3; CAMTA1; HEY2; ZNF410; ZNF10; NLK; SP4; NAB1; TSC22D1; PGR; BRWD1; HMBOX1; MEIS1; MDM4; PROX1; THRAP3; HOXD11; MBD2; ZNF175; FOXA1; HR; ZNF529; EGR4; NEUROD2; PRDM1; AGO2; SCAI; NKX2-2; TBX3; ZNF165; RFX7; HOXC6; ZNF682; ZNF117; HMG20A; SSX1; SP3; TAF12; TFAP2C; ERBB2; TXNIP; FOXG1; ZNF654; FHL5; LZTS1; MYT1L; ZNF75D; RSF1; JUNB; ZNF835; ST18; OVOL1; SRY; RXRG; ZNF493; ZNF222; PBX3; HIVEP2; NHLH2; YBX1; HDAC9; ZNF22; PCGF2; CITED1; ING3; TSC22D2; TAF9B; ZFHX4; ZHX2; OLIG2; HMGB2; SPIB; COPS5; MED14; GTF3A; SMARCA1; JUND; AFF1; HMG20B; NR3C1; ZFP36L2; RELB; TBX2; ELF5; ESR1; PBX1; TRIM29; ADRB2; MYBL1; TRPS1; NANOG; OSR2; E2F2; HOXC10; NFATC3; LEF1; SUV39H1; EGR1; TCFL5