Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID46546	Mepyramine	GSE70138	HA1E	Human	24h	0.123457uM	EID0220

Response Information :

Types	Number	Response transcription factors
Up-regulation	66	HTATIP2; BNC2; ZNF43; ZNF586; ZNF85; ZNF394; ZNF84; ZNF91; SMAD3; ZNF83; ZNF544; CNOT2; ZNF44; CBX3; TOX; HLTF; CREBL2; RNF138; ZNF134; ZNF430; CTBP1; ZNF573; DNMT3B; RREB1; ZNF337; SUB1; ZNF443; E2F3; ZNF266; PCGF1; PFDN5; GTF2IRD1; TULP3; TRIP6; TRIP4; MEIS2; IFI16; TAF10; HMGN3; IRF7; GTF2I; MXI1; ZFPM2; COPS2; ZFP36L2; APEX1; FOSL2; PLAGL1; IRF1; TRIM22; GTF3A; NR3C1; MED21; KLF7; HMGA1; HMG20B; KDM5D; NR1D2; ZNF423; KLF10; ELF3; ELK3; PUF60; NANOG; MAF; PPARG
Down-regulation	115	YAP1; NFAT5; HIPK3; MECP2; TRPS1; TRIP11; DLX2; HOXB9; BTAF1; SSBP2; CTNNB1; POLR2A; ASCL1; AFF4; DLX4; OSR2; TFEB; GATA2; DMRT1; SPI1; MBD2; MYB; SKI; TBL1XR1; TFAM; HOXB13; PRDM2; ENO1; LHX6; DLX5; HNF4G; TBX3; PAX6; KDM5C; RBBP7; HOXD11; FOXI1; NFATC1; FOXA1; ESRRG; TCF7L1; OVOL1; EN1; EMX2; PRRX1; KLF4; ZNF223; FOXN3; IRF6; MBD4; BBX; SREBF1; TULP4; CDK8; HES1; MEIS1; ZNF226; ZNF165; THAP11; ERG; BACH2; ASH1L; RARA; PIAS3; HMGB1; ZSCAN18; SIX3; PAWR; PGR; ESR1; MYBL1; HDAC4; HDAC9; IKZF1; EGR4; FLNA; HIPK2; GATA3; TERF2; ID3; IRX5; JUNB; HMGB2; NLK; EPAS1; TAL1; PCGF2; PAX5; WWP1; EGR2; IRF4; NKX3-1; MYRF; SNAI2; ZNF532; SSX1; SMARCA1; NKX2-2; EHF; LITAF; RELB; TBX2; HMGB3; TXNIP; TRIM29; BTG1; DACH1; SPIB; NFATC3; ADRB2; E2F2; PBX1; SUV39H1; TCFL5; GATA6