Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID46485	Ingenol-mebutate	GSE70138	HA1E	Human	24h	1.11111uM	EID0220

Response Information :

Types	Number	Response transcription factors
Up-regulation	70	NFKBIA; IRF7; FOSL1; PAX8; MAFB; MITF; HMGA2; BNC2; NKX3-1; TFAP2A; MEIS2; HNRNPD; ITGB3BP; TAF10; SP110; ARNTL2; ZNF91; TRIM22; RNF138; CENPF; RBM39; ZMIZ2; STAT1; SPEN; RBBP8; IFI16; TDRD3; MYBBP1A; TGIF2; ZZZ3; ZNF593; SIX1; COPS2; C1QBP; CAPN15; CNBP; POU2AF1; E2F2; TGFB1I1; CBX3; ZFP36L1; PAX5; FOXF1; WT1; MEOX1; RORA; EYA2; BHLHE41; MED21; MSX1; TRIM29; NR1H2; HOXB2; HHEX; NR3C1; FLNA; LOXL2; TLE4; EGR3; SSBP2; TRIP6; AES; PTTG1; HMG20B; NANOG; LEF1; FOXG1; CREB1; MAF; GATA2
Down-regulation	146	PEX2; MED23; CNOT1; TGIF1; NFATC1; ZNF536; BRF2; ZSCAN31; BRD2; HOXA10; ZNF165; MECOM; ETS2; ARL2BP; ID1; MYT1; TAL1; ZNF124; MYRF; NCOA2; ZNF532; ARID4A; HOXA5; PKNOX1; ESRRG; CBFA2T3; MED13; ARRB1; THAP10; ADNP2; TXNIP; HIPK1; TAF1D; LPIN2; SRF; GRHL2; E2F3; CSDC2; ZFP36L2; NCOR2; CUX2; PCGF3; TBL1XR1; ZNF184; ERG; EZH1; ILF2; RBL2; ACTL6B; NKX2-1; ZNF75D; PRDM1; LMCD1; NFAT5; FOXA1; DLX5; HNF4G; PAX1; ZNF140; ZNF22; ZNF217; CREB3L2; ZNF135; SMAD6; ZNF32; ZNF721; ZNF248; SIM1; CREB3L1; NHLH2; PPP1R13L; SMARCA2; TAF12; NR4A2; STAT6; NR3C2; IRF6; HDAC4; HES1; HSBP1; AGO2; CERS6; HDAC1; ZNF215; GATA6; EN1; NEUROD1; ZBTB20; BRWD1; SIAH2; ZBTB44; TSC22D3; HIPK3; ZSCAN18; INSR; TRPS1; CREM; MYB; ZNF227; TOB1; HMGB2; ZNF107; EPAS1; RXRA; ZNF665; PLAG1; ZNF222; NAB1; TSC22D2; KLF9; PLAGL1; IKZF1; RAD21; ZNF589; GFI1; CREBZF; NKX2-2; GATA3; TBX2; FOXN3; MED1; ELF3; ZNF516; OSR2; SERTAD2; FOXO4; TFEC; ZHX2; HOXC6; NR1D2; NFATC3; DACH1; KLF6; BCL3; TCFL5; ARNT2; ZBTB38; TWIST1; ATF3; ESR1; TOX3; MYBL1; TBX3; SPIB; ID4; RELB