Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID46484	Ingenol-mebutate	GSE70138	HA1E	Human	24h	3.33333uM	EID0220

Response Information :

Types	Number	Response transcription factors
Up-regulation	228	NFKB2; NFATC4; TFEB; FOSL1; STAT6; KAT2B; ELK3; TSC22D3; PLAGL1; MEIS2; MITF; MED16; PAX8; MYT1L; AR; SMAD3; NFE2; MED15; TRIM22; GFI1B; RORA; IRF1; GLI2; HMGA2; NFKBIA; ZNF573; POU5F1B; PIAS1; CRYM; ARID3A; NELFB; ZBTB32; ZNF710; PTRF; CTR9; HAND2; LIN28A; CIITA; DNMT3B; TULP3; BNC1; GLI3; ZNF267; CEBPA; KLF1; IFNB1; WT1; ZNF593; CBX3; SRCAP; BAZ2B; HHEX; MEIS1; FOXE3; HOXA3; BNC2; IFI16; HLTF; ZNF133; GATA1; ZBTB7C; NR3C2; ABT1; HDAC3; TCF4; PITX3; NANOG; LYL1; LMO1; IRF8; BATF; TULP2; TAF7L; ERF; SETDB1; PRRX2; POU6F2; EBF2; ZNF273; TBX10; ZNF672; KLF8; PML; SNAI1; ZNF780B; MED24; RFX2; THAP7; SMARCA5; TULP1; KLF4; CAPN15; SOX5; CARHSP1; HDAC5; ID4; SP110; REL; DMTF1; STAT1; ZNF208; ZBTB20; FHL5; MBD4; FOXL1; E2F2; CASZ1; SOX3; GTF2I; ASCL2; RBPMS; FOXH1; THRB; YBX2; RNF141; POU2F3; LHX6; EHMT1; ZNF80; UTF1; HLF; ZNF257; TAF10; INSM1; DOT1L; MKL1; ZNF23; HOXB8; MAPK8IP1; ZNF407; RCOR1; ZNF214; ZBTB7B; SUB1; COPS2; SP140; ZNF814; MED23; MYCN; POU2F2; ZNF674; GSC2; BRDT; ZIC3; PRDM12; DDX54; ERBB4; ACTL6B; ZNF81; PBX1; EGR3; SSX3; ELF2; POU1F1; GCM2; TLX2; NHLH2; EYA2; HIC2; JARID2; VHL; PAX4; SOX30; NEDD8; ZNF165; ZBTB16; NEUROD1; RXRG; ZNF493; ZSCAN16; MLLT1; ONECUT2; TGFB1I1; BAZ1A; PITX1; TCFL5; ZNF131; ZNF492; HAND1; NR4A1; NFE2L3; ALX1; PGR; JAK2; UBE3A; TSC22D2; CHD9; CREBL2; ZNF512B; NFIC; MXD4; VDR; ARID3B; ZNF623; DEAF1; SUV39H1; SMARCA1; NR3C1; NR5A2; SSX1; CEBPD; SLC2A4RG; TBX2; EDF1; BCL11A; IKZF1; TLE4; IRF4; GATA6; ZNF652; ZNF107; SOX11; HMGN3; PTTG1; PAX5; CITED2; TAL1; NKX2-1; IRF6; TRIP6; STAT4; ZFP36L2; ZBTB38; ADRB2; GATA2; PUF60; PSIP1; SOX9
Down-regulation	191	DNMT1; SOX4; PCBD1; TP53; AATF; CTCF; NFE2L2; HMGB1; ZNF587; SIM2; NKX3-1; RHOA; CNOT1; BHLHE41; BBX; NCOA1; HOXA10; KMT2A; TCF7; MNT; VEZF1; ZNF24; INSR; PEX2; CEBPG; HOXA5; CCNE1; PRKDC; JUND; HIF1A; AGO2; PKNOX2; ZNF331; SMARCE1; ATF4; SIRT2; BRD2; SATB2; HDAC4; CHD7; MED1; SMAD7; SUZ12; TDRD3; NCOR1; CERS6; TBL1X; HEY1; TBPL1; ZNF32; ZHX2; CCNH; ZNF266; ZIC1; BAZ2A; CBFA2T2; BRCA1; WHSC1; BCL10; NPAS2; TCF20; MAZ; ASCL1; FOXF1; DAXX; E2F3; SSRP1; HOXD1; TRAK1; PCGF2; YWHAB; IKZF5; MED17; BHLHE40; EN1; HOXB7; PCGF1; RUNX1; ZBTB18; CHD1; RBM39; NCOR2; HDAC1; TRPS1; SF1; ZNF354A; BTF3; NONO; ZNF14; ZNF45; FOXC1; TCF7L2; UBE2B; PCGF3; CTNNB1; ZNF148; CUX1; SRF; RBBP4; RARB; NFAT5; BANP; ZNF350; ZNF423; PRDM10; ID3; CLOCK; TULP4; PIR; ZNF302; MYT1; BRD8; SUMO1; RFXANK; AEBP1; HES1; NPM1; FOXD1; NCOA6; ZNF211; C1QBP; NFATC1; MBD2; HMGB3; TRIM29; CENPF; ZXDC; CDYL; ERBB2; CBX6; ZNF665; ZNF544; RLF; CDK8; ETV5; RYBP; NR2F2; OLIG2; E2F8; ZNF432; BRD7; GATAD2A; ENY2; TERF2; TCEA1; BRD4; JUNB; TRIM24; ZNF83; CREB3L1; TOX; RAN; ZNF93; CBFB; TLE1; ARNT2; SOX10; DDIT3; MYRF; SHOX2; TBX3; URI1; BTG1; ELF3; DACH1; FOXF2; YBX3; ZNF721; CRY1; TFDP2; RBBP7; BCL3; ZNF468; SMAD1; CD3D; ZNF160; MYB; FLNA; CRK; HDAC9; LITAF; EGR1; KDM5D; ID1; EMX2; POU2AF1; HMG20B; NFATC3; PEG3; ZNF586; RELB