Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID46483	Ingenol-mebutate	GSE70138	HA1E	Human	24h	10uM	EID0220

Response Information :

Types	Number	Response transcription factors
Up-regulation	65	IRF7; PAX8; RUVBL2; SMAD3; FOSL1; HMGA2; ELK3; SP110; NFKBIA; MAFB; MNDA; STAT1; NFKB1; ERCC3; TBL1X; ZFHX3; TAF10; ATN1; ZNF467; SMAD1; PFDN5; DAXX; HMGA1; AR; ZFHX4; DEAF1; TRIM28; MAFF; SOX11; DNAJC1; RNF138; BHLHE41; CEBPD; IFI16; MEOX1; CREM; KLF4; MED21; DNMT3B; NR3C1; TULP3; MECOM; TCF4; EYA2; EPAS1; TRIM22; BCL11B; YWHAB; CCNC; SIX1; IRF8; MAGED1; EYA1; HEY1; AHR; SSBP2; TSC22D1; HMG20B; WT1; ZFP36L1; HES1; LOXL2; GATA2; TRIP6; PUF60
Down-regulation	178	HOXA10; CTNNB1; INSR; TXNIP; CREB3L2; MYT1; ZNF112; ID3; FOS; NFIB; NFAT5; DPF2; BLM; CDIP1; ZNF177; BAZ2A; TRIM24; GRHL2; ZNF665; ZNF160; NEUROD1; ZNF34; ZIC3; ZNF124; EN1; ZNF117; ZNF711; ZNF721; ID2; ZNF232; SAFB; SKI; YAP1; OSR2; SNAI2; BAZ1B; INSM1; FOXK2; OLIG2; NAB2; ZNF10; ZNF611; SOX10; RSF1; ZNF235; TEAD1; EZH1; PCGF3; TFCP2; RXRA; MED13; HMGB1; AEBP1; ZNF813; TOB1; E2F5; ZBTB44; TCF7L2; PROX1; TBX1; RBBP7; ZNF14; PAX9; PRDM1; BRWD1; FOXA1; NCOA2; ZNF556; ZBTB39; STAT5A; TAF4B; ZKSCAN7; SP140L; ZNF682; RFX7; NHLH2; PRRX1; BACH1; HDAC5; ARID3A; KDM5D; ILF2; ZNF222; FOXF2; KLF11; CRYM; NKX2-1; TCF7; ZNF107; TCF20; ZNF141; PITX1; PRDM2; ADNP; CUX2; ID1; ZBTB20; LHX2; TWIST1; ZNF544; GATA3; PKNOX2; WNT4; TCF7L1; TTF2; IKZF3; NR0B1; TBX3; HIPK2; ZNF671; SERTAD2; HDAC1; TAF1A; ZNF195; ZNF350; HMG20A; ERBB4; LEF1; ZNF165; SOX18; NR1D2; MYB; SPIB; MED14; ZNF701; FLNA; FOXO1; SMARCA2; ZNF493; HOXD1; RAD21; MYCL; ZNF227; ARNT2; IKZF1; HOXC10; ZNF304; SIAH2; HDAC4; ZNF532; CHD7; ZNF551; CITED2; BACH2; GATA6; VDR; HLF; PITX2; ASCL1; NR4A2; ZBED2; NKX2-2; NFATC3; BCL11A; TRPS1; ZNF589; ID4; ETS2; MYBL1; TP63; ZBTB38; MYRF; RUNX1; KLF13; TBX2; HMGB3; ST18; TOX3; ADRB2; ELF3; ZNF586; BCOR; BTG1; TCFL5; ELF5; E2F2; SUV39H1; RELB