Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID46120	Pyrimethamine	GSE70138	HA1E	Human	24h	3.33333uM	EID0218

Response Information :

Types	Number	Response transcription factors
Up-regulation	88	NFATC3; MED14; KAT6A; CREM; SUV39H1; BANP; TAF5; PITX2; TOX; TCF12; ESR1; TWIST1; HLF; ZNF107; TAF11; NKX2-1; MED23; TBPL1; MKL2; ERBB4; ZFPM2; IFI16; PHIP; KLF13; EGR4; EGR2; SP100; PGR; FOXN3; ZNF423; CXXC1; MYB; NR4A3; POU2AF1; FOXG1; CARHSP1; ZNF516; PQBP1; PEG3; ANKRD1; EN1; SKIL; IRF7; BRD2; PIAS1; HTATIP2; PRDM10; HNRNPD; TCF7; MECOM; WWTR1; SMARCA1; PURA; TERF1; NANOG; CBFA2T3; WWP1; CDC5L; RBPJ; HMGN3; FOXO1; ETV5; IRF9; TCF4; SOX17; REL; IKZF1; REPIN1; ZNF331; SREBF1; PAX6; MXI1; EGR1; INSM1; OSR2; GATA2; PAX5; ARNT2; MSX1; EGR3; MYBL1; CRYM; ZNF160; ZBTB18; TFAP2C; ZBTB38; PPARG; NRIP1
Down-regulation	65	MAX; HIRA; TP53; CITED2; SREBF2; JAK2; TRAK1; NR2F2; FLI1; JUND; NFX1; HOXB7; RNF6; IRF1; NKX3-1; RBBP4; CIZ1; TSC22D1; ZNF432; CDK8; ZNF532; TRIP4; ZFP36L1; C1D; SMARCD3; CEBPG; MYCN; EYA2; WT1; CHD1; PFDN5; SSBP3; ZBED2; NR4A2; ERBB2; YWHAB; TGFB1; DMTF1; C1QBP; ZNF654; TP63; HOXB2; HOXB13; FOXD1; MAZ; FOSB; RORA; HMGB1; NFIB; KLF2; ZEB2; KLF6; NR0B1; DDIT3; TRIM29; SOX9; ELK3; ID4; ZSCAN18; FHL2; MAFB; E2F2; THAP11; NR3C1; HES1