Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID46019	Doxorubicin	GSE70138	HA1E	Human	24h	3.33333uM	EID0217

Response Information :

Types	Number	Response transcription factors
Up-regulation	161	ADRB2; FOXO4; SMARCD2; SNAI2; LDB1; TWIST1; L3MBTL1; MEF2C; EGR4; ETV1; TCEA2; KDM5B; KLF4; HLF; IRF8; ID2; CDX2; PHF1; FOS; TFAP2C; MYOG; SMAD3; YAP1; DACH1; ZBTB7A; REL; TGFB1; PEG3; SOX11; ATF5; MAFB; TOB1; TDRD3; SNIP1; BCOR; SNAPC4; RBFOX2; HIRA; ASXL1; MDM4; ING2; IRF6; MAFG; ZNF224; ZFPM2; ZBED2; TBX3; ZNF423; ZNF688; NFE2L1; EPAS1; MYB; NR0B2; KLF5; TCF15; PBX1; SIX3; LZTS1; NHLH2; ETV5; MEN1; TCF21; ZNF10; TADA3; ARID5B; HEY1; NR2F6; GFI1; ETV4; RRN3; BACH2; BRD2; ZNF331; KLF11; ZNF3; NR4A3; SREBF1; CDK9; NLK; OSR2; CUX2; HDAC9; BCL6; DBP; PCGF2; IRF9; RYBP; EN1; TBX2; DDIT3; ZNF467; MAF; MYRF; BTG1; SAP18; DR1; TCF7; TOX; RORA; ZNF43; WT1; PNRC1; YBX1; CERS6; HDAC4; DLX2; TEAD3; CAMTA1; FOXA2; NANOG; ZNF512B; AHR; NR1H3; GATA3; CERS4; HLX; TP63; TOX3; HHEX; TSC22D1; ZKSCAN1; MYT1L; ETS2; ESR1; FOXF2; PAX5; GTF2I; CHD4; ZNF211; BCL3; ARNT2; CREM; PBX3; ST18; TGFB1I1; VDR; KLF9; ZFP36L2; NR2F1; NKX2-1; CEBPZ; CEBPB; EHF; YBX3; TULP4; FOXO1; KDM5A; ID1; SOX9; TBL1X; IRF7; ZEB1; TGIF1; ERG; DAXX; ZNF91; MEIS1; HMG20B; ZBTB18; EGR2; CEBPA
Down-regulation	153	ATF6; XBP1; TCERG1; ECD; SMARCA4; HIF1A; MYBL2; NFKBIA; VPS72; NPAT; BRCA1; DNMT1; GABPB1; E2F3; ATF1; ARNTL2; HDGF; MNAT1; RBBP4; ADNP2; PMF1; ENO1; FOXD1; BLM; CCNA2; FOXC1; PSMD9; CUX1; PAX8; SSBP2; PSIP1; BCLAF1; CNOT2; BAZ1B; CBX3; TRIP6; MED12; ZNF148; ZNF146; SMAD4; SOX10; ADNP; ERBB2; ZNF143; WDHD1; TRIM32; TCF12; FLI1; SMARCC1; ING3; GFI1B; SUZ12; CENPF; SALL1; HCFC1; SSRP1; USF2; BRD7; NR2F2; SMARCE1; SMARCA2; CHAF1B; TRIM28; MED27; MED1; AFF1; PAX6; ORC2; MED7; RBBP7; ZNF292; ZNF302; HNRNPD; RBM14; MGA; PRKDC; RNF111; BRD3; NR3C2; DEK; ELK3; REST; STAT6; PSMC3; PPARG; ESRRG; CLOCK; VGLL4; NCOR2; MLXIP; OLIG2; NEDD8; OVOL2; MEIS2; MEOX2; DNMT3B; MTF2; FHL5; RUVBL2; HOXC10; C1QBP; PIAS1; CBFB; ZEB2; MAGED1; RNF141; APEX1; THAP11; HOXB7; SCMH1; ZNF468; TBL1XR1; IKBKAP; CBX5; NR1D2; SNW1; ID4; CREB5; SUB1; TLE2; ACTL6A; ZNF432; KLF2; NKX2-2; RREB1; KLF7; ZNF107; MED15; ZNF443; LMCD1; PURA; VEZF1; REPIN1; HOXA5; CREB3L2; PIR; ZNF32; KLF6; ZNF589; PQBP1; CALR; SAP30; KDM5D; SMARCA1; HOXC6; HOXB2; FOXG1; ZSCAN18; ZNF586; MECOM; SUV39H1; E2F2; TCFL5