Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID45924	Pyrimethamine	GSE70138	HA1E	Human	24h	0.37037uM	EID0217

Response Information :

Types	Number	Response transcription factors
Up-regulation	52	TFAP2C; ATF5; HMGB2; RBBP7; NR3C1; HIPK3; FOXD1; CTNNB1; TAF12; PRKDC; BTAF1; ID3; CALR; TGFB1; PMS1; TCEA1; JUND; ZNF337; LOXL2; ZNF654; MYBL1; FOXE1; MTDH; GTF2I; TAL1; TBL1XR1; ELF5; FOXF1; SAP30; DDX5; SIAH2; FLI1; HHEX; WWTR1; HLTF; DLX2; ZHX2; ZNF512B; ZFP36L1; SMARCB1; ZNF589; HEY2; TOX; SOX17; POU2AF1; EGR3; MSX1; ERG; MYB; MEIS2; HOXB6; NRIP1
Down-regulation	95	ING3; BAZ2A; ECD; ERBB2; NR2F2; ZNF148; THAP10; CCNT1; CREB3L1; SMARCC2; TRIM29; MED13; KLF13; ZNF222; CLOCK; RSF1; BRD2; PPARG; CREB1; ZNF136; RNF10; THAP1; NFE2L3; RYBP; HSF2; ZNF33B; MYCL; SREBF1; PBX3; DNMT3B; NFAT5; SAP18; HIC2; LMCD1; FOXC1; ZNF264; CDC5L; ZNF551; BNC2; TULP3; BTG1; MXD1; ZNF329; INSM1; ZNF14; KDM5D; BATF3; NFYC; KLF5; DACH1; WWP1; TOB1; BBX; HMGB1; TFAM; ZBTB38; FOXN3; ZNF468; ZEB2; TULP4; HMGN3; TRIP6; NFATC1; TBX3; CBX6; INSR; ELF3; TXNIP; TSC22D1; ZNF587; KLF2; TFEC; NR1D2; ZNF423; MEOX2; CEBPD; TOX3; SOX9; ZFPM2; ETS2; HOXC6; MAFB; ZNF91; THAP11; AEBP1; SUB1; ID1; PBX1; CEBPA; GATA2; E2F2; HES1; ZNF586; SUV39H1; EGR1