Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID45506	Sacubitril	GSE70138	HA1E	Human	24h	0.37037uM	EID0215

Response Information :

Types	Number	Response transcription factors
Up-regulation	87	EPAS1; TSG101; DEAF1; RARB; PPARGC1A; KLF3; ZBTB20; KLF9; RBBP4; KLF2; MED24; HAND1; PBX1; TSC22D1; CTR9; NR3C2; ENO1; HNRNPD; GTF2I; NFATC1; ZNF160; EGR2; REL; ADNP2; AR; ZNF165; ARID4A; NR4A3; FEV; TBL1XR1; ARNTL; ASCL1; ERG; SOX9; ATN1; HIPK3; HOXB13; FOXC1; RBBP7; AHR; HHEX; ZNF117; TULP4; ILF2; PLAGL1; TSC22D2; NR4A2; HLF; TCF7L2; NR4A1; NFE2L3; RBL2; STAT4; RBPMS; CREB5; CTBP2; IRF7; TGIF1; DLX5; HMBOX1; SMARCA1; TOX3; ZNF195; HMGB2; ZBTB16; GATA6; SMAD3; EGR3; NLK; DACH1; NR0B1; FOXG1; CITED2; TCF4; MYRF; CITED1; SUB1; NR1D2; ZBTB38; ID4; KLF6; HOXC6; IRX5; MEF2C; SOX11; NKX2-1; KDM5D
Down-regulation	45	BRD8; NRBF2; MLXIP; SETD2; MED21; PEX14; MED1; MECOM; CD3D; SNAI2; PLAG1; FOXD1; ZNF24; IRF1; VDR; ATF4; ZNF468; ZNF83; SMAD7; BATF3; IFI16; NRIP1; KLF10; MAFB; ZNF281; CEBPG; HOXB6; GTF3A; RNF6; POU2AF1; PEG3; MEIS2; MEOX2; TGFB1I1; HOXB7; RUNX1; ARNTL2; YBX3; NKX3-1; NR2F6; ID3; ERBB2; TFAP2C; ID1; SSBP2