Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID43569	Pevonedistat	GSE70138	HA1E	Human	24h	10uM	EID0205

Response Information :

Types	Number	Response transcription factors
Up-regulation	56	PPARG; ETV1; VGLL4; ETV5; MAFF; NFAT5; CREB5; GATAD2A; CDC5L; HHEX; ZFPM2; KMT2A; ATF3; NPAT; BHLHE41; BCL10; BCL6; CREM; ANKRD1; MAFG; HTATIP2; BBX; KLF13; NR2F2; RBBP8; FOXN3; LIMD1; BRD4; ZBTB43; EGR3; ZBTB20; E2F3; KLF6; NPAS2; RUNX1; HOXB7; ZBTB38; NR4A2; MECOM; INSR; NR0B1; TSC22D2; MEF2A; KLF9; TRIP6; DNAJC1; PDLIM1; TCF4; NFIB; HOXC10; NR4A1; PIR; FLI1; MEF2C; HOXC6; PEG3
Down-regulation	56	HIF1A; CCNA2; CEBPB; NFKBIA; PITX2; TP53; BRD8; CENPF; PMS1; EHF; MEIS2; HMGB1; HDAC4; MAGED1; ZNF302; EHMT2; ZNF146; NFYB; E2F5; ZBED1; ZNF32; STAT6; CENPB; TTF2; BCLAF1; ZNF12; HMGB3; DLX2; MAFB; PTTG1; SMAD6; TBX3; FLNA; ARID1A; ZNF165; ZNF580; MEIS1; MEOX1; TRIM22; CALR; ZFP36L1; HMGB2; HMGN3; ZHX2; PITX1; ZBTB18; ISL1; PBX3; LITAF; BTG1; LMCD1; PBX1; MYBL1; ESR1; ID1; SOX9