Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID42850	Binimetinib	GSE70138	HA1E	Human	24h	0.37037uM	EID0202

Response Information :

Types	Number	Response transcription factors
Up-regulation	21	HMGB1; PGR; POU4F1; BACH2; SAP30; TRIM22; SMAD1; IFI16; SP100; PTRF; IRF9; ZHX2; BTG1; IRF7; ESR1; MEOX2; TGIF1; POU2AF1; EMX2; FOXO1; LEF1
Down-regulation	40	EGR1; NR4A2; ZNF211; ZNF10; PBX3; ZNF331; EHF; HMGA2; PLAGL1; NR4A3; CBX6; TOX3; RXRA; FUBP1; EGR3; MED21; ID2; HMGN3; TSC22D2; NR4A1; TRPS1; NKX2-2; NR2F1; RUNX3; FOSB; BHLHE41; KLF4; MYCL; YBX3; MEF2A; HOXC6; TSC22D1; MEIS1; TAF9B; MYCN; WT1; SNAI2; ZBTB18; CITED2; MEF2C