Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID42849	Binimetinib	GSE70138	HA1E	Human	24h	1.11111uM	EID0202

Response Information :

Types	Number	Response transcription factors
Up-regulation	39	TCFL5; SSBP2; PPARG; ELF4; CEBPZ; IRF7; BCL3; PIR; ERG; ATF3; CHD7; KLF11; HIC2; VEZF1; WWTR1; OSR2; DDIT3; IFI16; E2F5; STAT1; SOX4; ZNF652; ZNF165; TSC22D2; RNF4; TRIM16; TCF21; JARID2; SLC2A4RG; PBX1; JUP; FLNA; HHEX; MECOM; ELK3; SMARCA1; FOXO1; ZIC1; DACH1
Down-regulation	36	EGR1; TSC22D1; FOXG1; CXXC1; UBE2I; HMGB1; LIMD1; PFDN5; TCEB2; NCOR2; CHD8; CTBP2; ID2; IRF8; ASCL1; PRRX1; STAT6; CEBPB; HMGN3; ZBTB38; DDX17; NFAT5; APEX1; NR4A1; MXI1; SOX9; TBX3; DLX5; HOXC6; HOXB6; ZBTB18; EGR3; ST18; MAFB; HEY1; MEF2C