Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID42665	Refametinib	GSE70138	HA1E	Human	24h	0.123457uM	EID0201

Response Information :

Types	Number	Response transcription factors
Up-regulation	60	NEUROD1; ATF3; BANP; PHOX2B; MLLT10; POU4F2; NHLH2; ZFPM2; ISL1; VGLL1; VEZF1; CREB3L2; EN1; SREBF1; ELF1; AIP; HOXC6; PAXBP1; MEOX2; GATA4; NR1H4; TGFB1I1; THAP10; FOXF2; HHEX; DDX17; SAP30; TCF12; RBL2; YAP1; HIRA; PCGF2; ZNF83; ZFP36L2; JUND; OSR2; PITX1; TCF25; GATA6; CAMTA1; HAND1; RBFOX2; BAZ1A; SMARCB1; FOXE1; CITED2; GTF3A; CEBPB; HMBOX1; MEIS2; TRIB3; INSM1; ZHX2; ARNT2; MEIS1; MYCN; PEG3; NFATC4; PBX1; ADRB2
Down-regulation	62	STAT3; ZNF562; CTR9; TFEB; DEAF1; RNF141; TAF10; SATB2; ZNF200; KLF10; PRKDC; HDAC4; IRX5; EGR3; NRBF2; EYA1; PEX2; CREB3L1; ZNF665; ZKSCAN1; PSMC3; HEY2; CRYM; TERF1; URI1; IKZF1; NCOA2; TCF3; ZNF266; ZNF426; ZNF611; TRPS1; NCOA1; MECOM; ZNF721; ZNF160; CTBP1; MYB; IRF7; CRK; BRD4; ZEB2; ZMYND8; ZSCAN18; BCL11A; ZNF91; MNDA; TXNIP; TCEB2; MYRF; DLX2; SOX10; LEF1; RUNX1; TWIST1; WT1; AEBP1; SIAH2; JUP; ASCL1; TOX; SOX2