Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID42662	Refametinib	GSE70138	HA1E	Human	24h	3.33333uM	EID0201

Response Information :

Types	Number	Response transcription factors
Up-regulation	65	STAT1; SOX4; CREM; NKX3-2; ELF4; SOX17; AIP; TRIM16; PFDN5; EPAS1; SMAD7; ZNF516; JUND; ARID1A; IRF9; PHOX2B; ZNF529; ATF4; NEUROD1; ZNF354A; ZNF532; NCOA6; GATA6; MBD2; ZFHX3; DDX17; HSBP1; HOXA11; ZHX2; EMX2; ESR1; BCL11B; ISL1; HIC2; HOXD11; FOXA2; ZNF652; HAND1; POU4F1; ZBED2; MSX1; TSC22D2; CERS6; INSM1; ZNF83; MYCN; SOX11; ATF3; CD3D; MEIS2; YBX1; PBX1; CREB3L2; CALR; TRIB3; IRF1; NFATC4; BACH2; HIRA; HOXB7; EHF; KLF4; CITED2; ADRB2; E2F2
Down-regulation	49	STAT3; DEAF1; CTR9; RNF141; PRKDC; ZKSCAN1; CRYM; ZNF562; NR1H3; KLF5; KLF6; NCOA2; TCF3; POU2AF1; KLF10; EGR3; CRK; ETS2; IKZF1; ZBTB16; BRD4; ZEB1; INSR; ZNF91; TRIP6; ZNF160; MAF; NR2F1; AR; IRX5; SOX10; SIAH2; FOXC1; AHR; LITAF; RUNX1; NFIB; FOXO1; HOXB2; NR2F2; ZEB2; BASP1; SUB1; SOX9; HMGA1; YBX3; ZIC1; HEY1; SOX2