Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID42483	Linsitinib	GSE70138	HA1E	Human	24h	1.11111uM	EID0200

Response Information :

Types	Number	Response transcription factors
Up-regulation	123	RELB; MBD1; TP63; SMARCD2; RARG; ZNF267; ZNF200; NR1H4; ZHX2; ZNF576; RCOR3; HLF; STAT6; MED13; CAPN15; MKL2; ZNF771; BNC1; ZBTB7C; SUPT4H1; NAB2; MLLT10; IFNB1; TRIM22; AIRE; SIAH2; ETV4; UTF1; NR0B1; EGR4; TRIM25; TTF2; SRCAP; SMAD4; CAMTA2; BCL10; MYBBP1A; ZBTB32; UBE2I; SSX3; IFI16; NR2C1; ELK4; UBE2B; HDAC9; IRF5; EPAS1; ZBTB24; TLX3; ZNF117; SOX21; HOXA1; CBFA2T3; JAK2; ZNF33B; KLF1; NOC2L; PAWR; GATA4; ZNF217; KLF3; TAF9; IRF2; ARL2BP; PRRX2; RARB; ATN1; STAT1; TERF2; RNF111; FHL5; CREB1; HOXC4; SNAI2; PITX2; TGIF2; HOXD3; LYL1; KDM5C; PRRX1; RNF10; BMI1; JUP; YBX3; ARNT2; MED1; NANOG; TLE4; RXRA; CITED2; IRF7; HIPK3; NCOA2; TCF3; SPIB; KLF5; YAP1; HSBP1; BAZ1A; OSR2; CTBP2; ELF3; IRF9; SP140L; CREM; TBL1X; TSC22D1; CUX2; ETS2; TGIF1; ZNF160; HOXC10; NR2F2; ZFP36L2; WT1; ERG; ZNF91; ID1; TGFB1; NFE2; CALR; MEF2C; SOX2
Down-regulation	99	THAP11; ZBTB1; YWHAB; ATF3; TSHZ2; ESRRG; MSX1; PBX3; XRCC6; HOXB2; CIR1; ZIC1; WWTR1; ZNF136; SHOX2; CREB3L1; NFIB; NCOA6; ZNF23; ZNF32; SUB1; HOXB7; JUNB; PAX6; CERS6; STAT5A; TSC22D2; ATF4; BCLAF1; ZFHX4; NFYA; ZNF415; MAGED1; ZFHX3; ZNF83; SETD2; URI1; CDK8; RBBP5; HSF2; BBX; NCOA4; SATB2; ZNF580; ENY2; DNAJC2; SIM2; PLAGL1; PIAS3; SMAD7; ELF5; CDC5L; HLTF; FOSB; MBD2; FOXF1; BRD2; FOXF2; MECOM; ZBTB18; RBM39; MNDA; MXI1; NLK; ATF2; SIX1; INSR; RBPJ; ZNF394; ZNF423; SP100; EYA2; GTF3A; SIX2; RUNX1; KDM5D; PRPF6; HEY2; ZEB1; PUF60; RORA; PCGF2; HMGB1; LOXL2; JUND; TXNIP; BHLHE41; EDF1; EGR3; SMARCA1; HMBOX1; TRPS1; TOX3; NFATC3; KLF2; HEY1; BRCA1; EGR1; DAXX