Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID42480	Refametinib	GSE70138	HA1E	Human	24h	0.0411523uM	EID0200

Response Information :

Types	Number	Response transcription factors
Up-regulation	70	SCAND1; MED7; ZNF148; CARHSP1; ZNF44; ZNF266; RCOR1; TBX1; SMAD1; SMARCB1; BTAF1; KLF11; ARRB1; MYRF; MAZ; NFE2L3; SMAD6; ZNF32; TCF3; PIAS1; ZHX2; CREB1; PBXIP1; RNF141; HLF; STAT3; CALCOCO1; ZNF430; TRAK1; KLF6; ZNF721; MAX; GATA6; MYB; ZNF189; ZMYND8; TRIB3; IRF7; KLF2; ZFP36L1; ARNTL; ZBTB20; BRCA1; VDR; FOXN3; ATN1; TXNIP; POU4F1; KLF4; EPAS1; HIPK3; ZNF91; KLF9; RORA; MED1; EMX2; EDF1; MECOM; KDM5D; ID3; HMGB2; FLNA; TBX3; ELF3; ID1; MEF2C; TCF4; NFATC4; LEF1; NR4A2
Down-regulation	61	NPAS2; MSC; CEBPB; ISL1; TP63; KLF13; EN1; PBX3; DLX5; CREB3L2; SIX3; HOXB5; EP400; HHEX; TRIM29; HEY1; ZNF532; PIR; TFCP2L1; PIAS3; AGO2; IRX5; FOXE1; PRKDC; INSM1; CHD7; OSR2; FOXC1; HOXB6; ELF5; EYA1; TRIP6; SNAI2; FOXL2; PUF60; FOXA1; ETS2; ASCL1; AR; HSF1; TCF7L1; HOXC6; TSC22D1; SOX2; JARID2; LITAF; NAB1; TBL1XR1; NKX2-1; ZIC1; MAFB; HEY2; SOX9; ZFPM2; FOXG1; NFATC3; BASP1; MNDA; NR2F2; EGR1; EGR3