Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID42479	Refametinib	GSE70138	HA1E	Human	24h	0.123457uM	EID0200

Response Information :

Types	Number	Response transcription factors
Up-regulation	56	HIF1A; ZNF131; SMAD3; POU2AF1; TGIF2; ZNF273; CBFB; ZNF711; BCL6; IRF9; SAP18; KLF4; BACH1; PMS1; SMARCC2; ZNF195; ERF; CREB1; CREM; PLAGL2; TAF9; HIRA; IRF7; PAX5; YEATS2; TERF2; MECOM; HOXA1; TCF25; RNF14; IFI16; PCGF1; IRF8; SP110; SLC2A4RG; EYA2; RNF141; BCL11A; STAT1; MED1; HMGB2; EMX2; KLF6; MEIS1; MYCN; YBX3; CARHSP1; PCGF2; MSX1; SATB2; MEF2C; KDM5D; TFAP2C; TXNIP; NFATC4; LEF1
Down-regulation	75	PRKDC; INSM1; MSC; NR2F1; SP2; PTRF; VGLL1; NFIB; ZNF83; SOX13; PBX3; HOXB2; ZFPM2; NFIX; LITAF; TBL1XR1; PLAGL1; IRF4; RSF1; SMARCA2; TOX3; MTA1; LHX2; ZBTB18; ZBED2; FOXE1; JUNB; NR5A2; ZEB1; COPS5; ATF3; IL16; AGO2; MYT1L; UBE2B; EGR3; PIR; HHEX; HMGA1; EHF; MITF; CALR; PUF60; TERF1; ARNTL2; HOXB6; FOXO1; ZBTB16; PEG3; SNAI2; NR4A2; SOX2; AHR; TAL1; ZIC1; ZNF91; MEIS2; MEOX2; ZBTB20; NR1D2; NR4A1; HEY1; TBX3; PITX1; FOXG1; TRPS1; PBX1; ASCL1; BRCA1; BASP1; EGR1; ID4; SOX9; BHLHE41; DAXX