Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID42477	Refametinib	GSE70138	HA1E	Human	24h	1.11111uM	EID0200

Response Information :

Types	Number	Response transcription factors
Up-regulation	53	BATF3; EGR2; SCAND1; HOXC6; GATAD2A; DAXX; CD3D; TAF11; SUPT4H1; ZNF266; ATF3; MYRF; KLF7; NR4A1; CUX1; ITGB3BP; NR0B1; MED13; PBXIP1; TBX21; MYBL1; SP140L; BCL11B; EGR1; STAT4; BNC2; CITED1; TRIB3; IFI16; HOXB7; EGR3; NFE2L3; ESR1; BRCA1; CARHSP1; HTATIP2; IRF8; ARNTL2; PIR; OSR2; SUB1; FOSB; TRIM16; MAFB; GATA6; RBPMS; GRHL2; KLF2; E2F2; IRF7; KDM5D; NFATC4; LEF1
Down-regulation	90	TAF4; BCLAF1; SMARCB1; HMGA1; DDX17; PATZ1; DLX5; SF1; TGFB1; DACH1; ZNF816; FOXG1; E2F5; NFIB; ZHX3; SMAD7; CUX2; IKZF5; ZNF571; MYT1L; DLX2; TMF1; MTA1; SMARCA2; TRPS1; BAZ2B; MBD2; NR2F1; XRCC6; ZNF443; SPIB; LHX2; ZNF529; ZNF512B; PAX6; ING3; SOX11; HEY1; NR1H3; SFPQ; CBFB; ZSCAN16; HSF1; ELF5; AGO2; CAPN15; MTDH; MAF; SMAD1; FOXN2; CNOT3; SOX9; CHD7; GTF2I; SATB2; YBX1; PUF60; IRX5; MED24; PRKDC; HIPK3; IL16; ASCL1; DEK; BACH2; FOXC1; ERBB4; SOX2; MEF2C; ZNF281; HEY2; SMARCA1; JUND; ZNF91; MAGED1; HHEX; ZFP36L1; PBX3; PAX5; RBPJ; ZIC1; ELK3; ZSCAN18; KLF9; KLF5; TFAP2C; NR1D2; JUP; TCF4; NFATC3