Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID42476	Refametinib	GSE70138	HA1E	Human	24h	3.33333uM	EID0200

Response Information :

Types	Number	Response transcription factors
Up-regulation	73	THAP7; SMARCD2; ARNT2; NR1H2; HES1; STAT3; TRIB3; FOXD1; TP63; ZBTB16; LHX2; AR; MYBL1; SHOX2; MEIS2; RBM39; ZHX2; REL; ZNF580; NKX3-1; CEBPA; KAT2B; TCEA1; TFAP2C; TFEB; FOS; TLE2; MNAT1; PAX5; ZFP36L1; TULP3; MZF1; PSMC3; KLF11; ZNF195; SOX13; SIM2; SALL1; HOXC10; ARNTL; TAL1; IRF9; PIAS3; NCOR1; CEBPB; SPIB; CNOT2; FOXG1; NR1H3; SUB1; TGFB1; THAP10; TRPS1; STAT1; AES; EGR1; TOB1; TBL1X; BRCA1; BHLHE41; INSR; LITAF; POU2AF1; TOX; YBX3; FOXF1; HHEX; RBPMS; EGR3; TCF4; SOX2; PUF60; MEF2C
Down-regulation	84	NR1I2; ETV7; MLXIPL; NRIP1; MYC; KDM2A; ARRB1; RBM14; SNIP1; UBP1; ZNF329; NHLH1; MED1; BAZ2B; NR2F6; POLR2A; MXD1; IFNB1; YAP1; NEUROD1; ZNF22; MYRF; E2F3; HOXD1; SFPQ; CDX2; PRRX2; WHSC1L1; BBX; INSM1; ATOH1; BCL11A; NHLH2; TSC22D4; HTATIP2; MTF2; MEOX1; BRD3; NFAT5; ELF2; BRPF1; ZNF124; SMAD6; NR1D2; ZNF189; ASH2L; DACH1; TRAK1; ZFP36L2; FOSL2; CAMTA1; ZEB2; MNT; KLF10; ZNF721; CAPN15; KDM5D; FOXN2; MDM4; ID4; CARHSP1; HIPK3; AHR; IRF8; ZNF165; MYCN; STAT4; JUND; NFATC4; TFAM; TOX3; WT1; ASCL1; MED24; ZBTB20; ZSCAN31; GATA6; PEG3; ELK3; NR4A2; OSR2; ZBTB18; MYB; DAXX