Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID42475	Refametinib	GSE70138	HA1E	Human	24h	10uM	EID0200

Response Information :

Types	Number	Response transcription factors
Up-regulation	51	TGFB1I1; BRIP1; ARID5B; WNT4; TEAD4; ZNF580; AIP; ZHX2; STAT1; MYBL1; ALX1; IRF9; HOXC6; LOXL2; CREB3; MEIS2; DNMT1; CREB3L2; HOXC10; ZNF131; HDAC5; ARNT2; VDR; PPP1R13L; PSMC3; TCF25; ZNF532; TRIM16; HSF1; JUND; IRF7; TLE4; RBFOX2; HOXA11; PLAGL1; BASP1; NR4A3; SMARCA1; STAT3; RBPMS; DLX2; CITED2; RAD21; TFAP2C; SOX10; POU2AF1; TGFB1; MEF2C; HOXA10; PUF60; BHLHE41
Down-regulation	53	FOSL1; CTBP1; USP22; ING3; MYC; MECOM; ZNF136; ARNTL2; EHF; EGR4; CIITA; BBX; CCNE1; AEBP1; CBX6; NEUROD1; MYCN; OVOL2; TFDP2; TERF1; HDAC4; IRF1; ZNF551; HMGA1; MXD1; INSR; PIR; MAFB; ZBED2; ZBTB18; ZNF165; PRKDC; ASCL1; TFEC; OLIG2; KLF9; MYB; ZSCAN18; INSM1; ZEB2; SOX2; SNAI2; ZNF423; ETS2; WT1; NR1D2; NR2F2; SOX9; BRCA1; TXNIP; EGR1; TOX3; DAXX