Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID42293	Refametinib	GSE70138	HA1E	Human	24h	0.37037uM	EID0199

Response Information :

Types	Number	Response transcription factors
Up-regulation	43	CDK8; CDYL; MAGED1; JARID2; LMCD1; SALL2; TRIM22; NFKBIA; LIN28A; CERS6; SP110; CITED1; ZBTB20; IRF1; IRF4; PKNOX2; HTATIP2; NFE2; ZNF711; CARHSP1; STAT1; GATA6; IRF8; TSC22D2; STAT4; ZNF91; TFDP2; EGR3; BCL11B; TOX3; IRF7; KLF10; ASCL1; CREB1; RORA; TRIP6; BASP1; LEF1; LOXL2; ZIC1; NKX3-1; IKZF1; KDM5D
Down-regulation	40	BRD7; LDB1; KLF5; NR2F1; AHR; HEY2; NR4A2; KLF1; NR1H4; JUP; BHLHE41; SATB2; ARNT2; TBL1X; SMARCC2; MEF2A; ELF3; ERG; CITED2; FOS; FOXG1; MAF; EYA2; KLF4; EPAS1; KLF6; TRIM29; SOX9; MEIS1; HOXC10; ID1; YBX3; TBX3; TSC22D1; HEY1; MEIS2; NFATC4; PBX1; SSBP2; MEF2C