Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID41612	Afatinib	GSE70138	HA1E	Human	24h	10uM	EID0195

Response Information :

Types	Number	Response transcription factors
Up-regulation	61	TRIB3; DNMT1; DDIT3; NCOA3; TSC22D3; PAX8; FOSL1; ATF5; BANP; ARNT2; TOB1; ZNF557; CEBPB; THAP7; TAF5; NAB2; CBX6; RXRA; PCGF1; TXNIP; CREBL2; THAP10; MLX; HDAC9; HIRA; MXI1; SIM2; SMARCD2; INSR; STAT3; FOXF2; TFAP2C; TFAP2A; PHF20; ETV5; VDR; HOXD1; TSC22D1; ERBB4; SERTAD2; ZNF91; TCF7; TULP3; CEBPG; HMGA1; PCGF2; RUNX1; TLE2; SOX9; ATF3; ZNF12; BHLHE41; NKX3-1; ZNF217; NPAS2; OSR2; PBX3; HOXB2; TRPS1; ZNF331; CEBPA
Down-regulation	77	MYCBP; CCNA2; SOX4; FHL2; GMNN; HOXA10; NFKBIA; TCERG1; BIRC2; NFIL3; EZH2; CRY1; SMAD3; C1QBP; SIAH2; CENPF; HMGB3; ZNF22; PLAGL1; CHD7; SMARCC1; MSC; BMI1; SMAD7; ID3; TAF1D; TCF12; SUB1; ENY2; RAN; PRKDC; TCF21; TGFB1I1; TAF11; HLTF; LOXL2; MAGED1; FOSL2; RORA; RBM14; PTTG1; ZEB2; YAP1; KLF7; NKX2-1; KLF2; NRIP1; MEOX2; ZBTB20; KLF10; TSC22D2; TOPORS; IRX5; SMARCA1; RBBP4; EGR3; INSM1; MSX1; RBBP8; EYA1; MYCN; ZNF423; ID4; TOX3; MEIS1; POU4F1; TLE4; KLF6; WWTR1; TCF4; ASCL1; ZIC1; KDM5D; E2F2; NFKB2; MNAT1; ADRB2