Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID39659	Amonafide	GSE70138	HA1E	Human	24h	10uM	EID0185

Response Information :

Types	Number	Response transcription factors
Up-regulation	100	NR1H2; TCEA2; DRAP1; ADRB2; TCFL5; TRIM22; CEBPZ; ETV5; HCFC2; SIRT7; TP63; RB1; ZNF268; SP140L; TOB1; CAMTA2; ANKRD1; MDM2; ZNF211; THAP10; ATF5; KLF13; CDIP1; MLXIPL; FOXI1; YBX3; OLIG2; CDK9; EHF; RNF6; TRIM29; TOPORS; BRD2; ZXDC; ZNF432; ZNF654; STAT1; SAFB2; ATF3; ZNF45; NR4A2; CBX6; ARID5B; ZNF83; SATB2; FOXA2; ZNF415; NPAS2; MAF; ZNF512B; SP110; ATF7IP; DDIT3; ELK3; CBX7; IRF6; IFI16; ZNF195; IRF9; KLF11; FOSL2; TFAP2C; KAT2B; MYB; CUX2; E2F2; PBX3; DACH1; CHD9; BRD4; TBX3; ZBTB43; BHLHE41; BBX; PEG3; ZNF331; SMARCA2; MYCL; ZNF468; HDAC4; ZKSCAN1; FOXG1; FOXF2; IRF8; AR; HOXD1; HLF; EYA2; NKX3-1; CITED1; SNAI2; TRPS1; ARNT2; INSR; ZBTB20; POU2AF1; MEIS2; KDM5D; OSR2; CEBPA
Down-regulation	84	XBP1; CCNA2; PCBD1; MYC; PARP1; NFKBIA; NPM1; ABL1; FOXM1; NONO; CENPF; SND1; PQBP1; NUP62; RHOA; GABPB1; PTTG1; ENO1; SMARCC1; EZH2; SAP30; SUPT3H; CARHSP1; MEOX1; NR2F2; NFIL3; SMARCE1; HNRNPD; CBX5; JARID2; ATF4; RBM14; SOX4; ZHX2; GTF2I; TEAD4; SIAH2; UBE2I; APEX1; PAX6; HSBP1; ZNF146; HOXC6; MEOX2; E2F3; E2F5; MAX; YEATS4; HMGB3; SMAD6; UBE2B; WWC1; IRX5; ERBB2; HMGB2; TBL1XR1; HOXC10; CTBP2; PITX2; LMCD1; TRIM16; ZNF711; ASCL1; WT1; BNC2; MAZ; ID2; FOXD1; TGFB1I1; KLF2; AEBP1; ID1; PURA; MYBL1; KLF6; ZFPM2; TSC22D1; INSM1; ID4; TLE4; TBL1X; MEIS1; NFKB2; MEF2C