Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID38021 Roflumilast GSE70138 HA1E Human 24h 1.11111uM EID0176
Types Number Response transcription factors
Up-regulation 24 PITX2; ARRB1; ZBED2; BRCA2; RSF1; SOX17; ZNF140; SP140; GTF3A; TAF9B; IKZF1; IRF1; EPAS1; VGLL1; HIPK3; CITED1; IL16; ELK3; FOXO3; MYRF; EHF; MYT1L; IRF4; RBPMS
Down-regulation 22 FOXJ1; MAF; MEIS1; UBE3A; PTTG1; NFAT5; TOB1; HMGB3; TRPS1; HMGB2; ZBED1; SIM2; HDAC1; LEF1; FOSB; TOX; ATF3; LOXL2; MYB; BTG1; NR4A2; HEY1