Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID36730 Vardenafil GSE70138 HA1E Human 24h 10uM EID0169
Types Number Response transcription factors
Up-regulation 156 RELB; GATA2; MAFB; GATA3; BACH1; RARA; ZNF200; HOXC4; HOXB9; ZNF423; POU2F2; PHOX2B; EZH1; ZNF22; BRD4; TOPORS; NFAT5; FOXN3; ZSCAN32; KLF13; ZNF148; TERF2; ZBTB43; BLM; CAPN15; SIM1; PPP1R13L; NFATC3; E2F1; CHAF1B; TTF2; PITX2; SREBF2; IRF1; CTR9; NFE2L3; TAF7; SRCAP; ESRRA; PHOX2A; NCOA2; NRBF2; TWIST1; ZHX2; CD3D; HDAC5; ARNT; MKL1; SMARCA2; HAND1; NCOA1; KLF3; CALCOCO1; CREB5; ZNF140; ELF2; CUX1; ACTL6A; ZNF266; MED7; THAP4; TAF12; PLAGL2; NFE2L1; KLF2; HIVEP1; CDX1; RNF141; TCF20; BTG1; ZNF32; PEX2; SIX3; VDR; KLF7; SKI; HMGB1; KDM5A; IKZF1; PRKDC; LMCD1; SOX9; SP3; UBE2B; SP110; BACH2; SETDB1; RSF1; PCGF3; ZBED1; ASCL1; LHX2; TGIF1; TFAM; ZNF232; ZNF576; SP2; TBL1XR1; LPIN2; DLX4; SOHLH2; MYRF; ETS2; ZFPM2; ZNF281; DLX2; EP300; TDP2; HOXC8; RYBP; KLF4; MED17; PBXIP1; MYCL; LEF1; TBX3; PPARGC1A; NCOR2; THRAP3; ARID3A; RXRA; ATN1; CDIP1; OVOL1; MSC; ZNF654; NEUROD2; DLX5; ZBTB18; GFI1; KLF6; HIC2; IRF4; SMARCC2; ZSCAN18; TRIM22; ID1; ZNF532; ID3; TAL1; IRF6; CBX5; SSX1; TBL1X; VGLL1; STAT3; JUP; MED13; EYA1; CREG1; KLF9; ERBB4; TRIB3; MYT1L; KDM5D; MXI1
Down-regulation 103 PUF60; HOXA10; NR2F6; DNAJC2; PTTG1; ARID4B; ZNF394; CTBP2; MITF; HOXB6; CENPF; ZNF574; TOX4; ZNF667; LITAF; GTF2F1; HMG20B; HOXB5; ZMIZ2; PRPF6; APEX1; HMGB3; RBM39; BTAF1; SSRP1; REPIN1; ZNF692; TRIM16; SFPQ; HDAC1; NEDD8; EYA2; FOXL2; ZNF134; HOXA11; ELF4; ZNF135; MTDH; NR2F2; WWTR1; C1QBP; ZNF587; MAF; TADA3; PIAS2; RLF; ZNF473; TAF9; ZNF7; MAFF; CBFB; ZSCAN31; SOX17; BMI1; ENY2; RUVBL2; TRIM28; HOXA5; HOXB7; MED27; RNF138; PCGF2; NR2F1; TDRD3; ITGB3BP; TAF10; PHIP; HDAC9; LOXL2; HTATIP2; HDGF; TGFB1I1; PLAGL1; NR1H3; PTRF; BHLHE41; ZNF34; TLE1; ZNF580; TFEC; CITED2; TOX; SOX10; ELF5; YWHAB; TRIP6; YBX1; RERE; BCL11A; KAT2B; SHOX2; RUNX3; FOXC1; HEY1; MEIS1; ZBTB38; PBX1; IRF8; WT1; TSC22D1; HHEX; CEBPA; E2F2