Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID36593	Rociletinib	GSE70138	HA1E	Human	24h	10uM	EID0168

Response Information :

Types	Number	Response transcription factors
Up-regulation	113	CEBPD; SPDEF; NR1H2; TBX2; NFYC; TCEA2; PPARG; TRIM33; SATB2; ZHX2; TAF5; HEY2; FOXJ2; NANOG; ARID5B; KLF11; MYNN; SAFB2; CREBL2; ZNF235; ZNF264; ZNF239; TDP2; MAFF; REL; MNDA; STAT5A; ZNF140; THAP10; TFEB; ZNF331; BCL11A; JUNB; BRWD1; HIVEP1; ZNF423; HIPK1; TRIB3; HHEX; ELF5; SMAD4; PHIP; INSR; FOXF2; HIRA; OLIG2; NFKB1; TFAP2A; DDIT3; CBX7; ZNF532; ARNT2; HLX; SOX10; MXI1; FOS; SMARCD2; KLF5; TP63; ETV5; TCF7L2; LITAF; SPIB; SOX13; TGIF1; JUP; PBX1; KAT2B; RYBP; RUNX1; ZNF500; CITED2; KLF4; ZNF512B; ZNF91; HDAC9; NCOA3; BANP; TRIM29; NR4A3; POU2AF1; LIN28A; CRYM; FOXC1; HMGA1; ATF3; DNMT1; DLX2; TCEA1; ZBTB16; TOB1; CREM; RORA; SOX9; ERBB4; MYCL; YBX3; TFAP2C; ZNF580; MYBL1; FOXG1; HEY1; ID4; ST18; MEIS2; TLE4; PBX3; PIR; ESR1; KDM5D; PEG3; STAT3; TOX3
Down-regulation	67	HIF1A; GTF2A2; SMARCE1; MAGED1; CCNA2; MYC; CBX3; YAP1; RHOA; WWTR1; ZNF22; CDK7; AFF1; HMGB1; CENPF; PAX8; HMGN3; HOXA5; ARNTL2; BHLHE40; HDAC1; RAN; KDM2A; NPAT; HOXB7; LEF1; HLTF; GTF2IRD1; ELK3; YWHAB; HSBP1; SMARCA1; SMAD3; MLXIP; BCL11B; HOXA1; RUVBL2; PTTG1; NR2F2; FOSL1; ENO1; HOXC6; CARHSP1; ID2; HNRNPD; MSX1; TFDP2; MEOX1; ZMYND8; ZBTB18; SIX1; PITX2; RUNX3; IFI16; SFPQ; ID3; NRIP1; BMI1; EGR2; ZBTB38; TWIST1; CTR9; SMAD1; RBPMS; ERG; TCF4; E2F2